Xin Zhang

ORCID: 0000-0002-5966-0471
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Research Areas
  • Acupuncture Treatment Research Studies
  • Traditional Chinese Medicine Studies
  • Autophagy in Disease and Therapy
  • Healthcare and Venom Research
  • COVID-19 epidemiological studies
  • Medical Research and Treatments
  • Liver Disease and Transplantation
  • Viral Infections and Outbreaks Research
  • Liver Disease Diagnosis and Treatment
  • COVID-19 diagnosis using AI
  • RNA regulation and disease
  • Cervical Cancer and HPV Research
  • Mycobacterium research and diagnosis
  • Misinformation and Its Impacts
  • Data-Driven Disease Surveillance
  • melanin and skin pigmentation
  • Hepatitis B Virus Studies
  • Meta-analysis and systematic reviews
  • Restless Legs Syndrome Research
  • Alcohol Consumption and Health Effects
  • Technology and Human Factors in Education and Health
  • Medical Imaging and Analysis
  • Biochemical Analysis and Sensing Techniques
  • Advanced X-ray and CT Imaging
  • Children's Physical and Motor Development

Third Hospital of Hebei Medical University
2025

Hebei Medical University
2012-2025

Fudan University
2024

Second Affiliated Hospital of Xi'an Jiaotong University
2020-2024

Peking University Shougang Hospital
2024

Renmin Hospital of Wuhan University
2024

Wuhan University
2024

Institute of Software
2023

Shandong University of Traditional Chinese Medicine
2023

Tianjin Medical University
2020-2022

Background Cirrhosis is a disease that imposes heavy burden worldwide, but its incidence varies widely by region. Therefore, we analysed data on the and mortality of cirrhosis in 204 countries territories from 1990–2019 projected development 2019–2039.

10.1080/07853890.2024.2328521 article EN cc-by-nc Annals of Medicine 2024-05-10

Background and Aims: The complications of liver cirrhosis occur after long asymptomatic stages progressive fibrosis are generally diagnosed late. We aimed to develop a plasma metabolomic–based score tool predict these events. Approach Results: enrolled 64,005 UK biobank participants with metabolomic profiles. Participants were randomly divided into the training (n=43,734) validation cohorts (n=20,271). Liver defined as hospitalization for or presentation HCC. An interpretable...

10.1097/hep.0000000000000879 article EN Hepatology 2024-04-17

This retrospective study aimed to explore the effect of erector spinae plane block (ESPB) on gastrointestinal function in patients after traumatic lumbar fracture surgery and effects different levels approach. Clinical data were retrospectively analyzed from electronic medical records who underwent spine (September 2022-June 2023). Eligible divided into three groups: group L (bilateral ESPB at L3 level), T T12 level) C (no block). The primary outcomes incidence time occurrence postoperative...

10.2147/jpr.s492380 article EN cc-by-nc Journal of Pain Research 2025-03-01

Background: During the Coronavirus Disease 2019 (COVID-19) pandemic, frontline nurses face enormous mental health challenges. Epidemiological data on statuses of remain unknown. The aim this study was to examine (burnout, anxiety, depression, and fear) their associated factors among who were caring for COVID-19 patients in Wuhan, China.Methods: A big-scale cross-sectional, descriptive, correlational design used. total 2,014 eligible from two hospitals China, participated study. Besides...

10.2139/ssrn.3566144 article EN SSRN Electronic Journal 2020-01-01

Waardenburg Syndrome (WS) is an autosomal-dominant disorder characterized by sensorineural hearing loss and pigmentary abnormalities of the eyes, hair, skin. Microphthalmia-associated transcription factor (MITF) gene mutations account for about 15% WS type II (WS2) cases. To date, fewer than 40 different MITF have been identified in human WS2 patients, few these were Chinese descent. In this study, we report clinical findings mutation identification 20 patients from 14 families. A high level...

10.1371/journal.pone.0077149 article EN cc-by PLoS ONE 2013-10-23

Sleep disturbances are common in people with autism spectrum disorder (ASD), but research on this topic is still limited China. In the current study, we evaluated prevalence of sleep problems preschool-aged children ASD and to examine correlations between emotional/behavioral symptoms repetitive behavior unique social context This study recruited 475 aged 3-6 years old, including 252 (mean age 5.13 ± 1.15, 80.6% male) 223 age-matched typically developing (TD) 5.12 0.97, 74.9% male). The...

10.3389/fpsyt.2020.00273 article EN cc-by Frontiers in Psychiatry 2020-04-16

Bloodstream infections (BSIs) are a frequently observed complication in liver cirrhosis patients. This study aimed to investigate the microbiological characteristics and outcomes of BSIs patients with cirrhosis. We retrospectively studied 852 who developed BSI. Patient outcome was evaluated using 30-day mortality assessed multivariate stepwise logistic regression analysis. Antibiotic sensitivity pathogens tested. Gram-negative bacteria were responsible for 59.6% BSIs, Gram-positive caused...

10.1038/s41598-017-11587-1 article EN cc-by Scientific Reports 2017-09-11

Background: Hemorrhagic fever with renal syndrome (HFRS) is a serious public health problem in China, and primarily caused by either the Hantaan virus (HTNV) or Seoul (SEOV) strains. However, causative hantavirus has only been definitively identified few HFRS cases, detailed comparisons of patient data for 2 strains are limited. Methods: We conducted 1-y prospective study Heilongjiang Province, China. A total 152 patients from 3 hospitals met diagnostic criteria used The diagnosis was...

10.3109/00365548.2011.566279 article EN Scandinavian Journal of Infectious Diseases 2011-03-24

Sleep disorder emerges as a common comorbidity in children with autism spectrum (ASD), and the interaction between core symptoms of ASD its sleep remains unclear. Repetitive transcranial magnetic stimulation (rTMS) was used on bilateral dorsolateral prefrontal cortex (DLPFC) to investigate efficacy rTMS comorbid problems well mediation role intervention improvement. A total 41 Chinese who met criteria fifth edition American Diagnostic Statistical Manual Mental Disorders were recruited, 39...

10.3389/fpsyt.2021.820598 article EN cc-by Frontiers in Psychiatry 2022-01-24

The Ebola virus causes an acute, serious illness which is often fatal if untreated. However, factors affecting the survival of disease remain unclear. Here, we investigated prognostic (EVD) through various statistical models.Sixty three laboratory-confirmed EVD patients with relatively complete clinical profiles were included in study. All recruited at Jui Government Hospital, Sierra Leone between October 1st, 2014 and January 18th, 2015. We first whether a single presentation would be...

10.1371/journal.pntd.0004113 article EN cc-by PLoS neglected tropical diseases 2015-09-23

Gastric cancer (GC) is one of the most frequent epithelial malignancies worldwide. The gastrointestinal (GI) peptide gastrin an important regulator secretion and release gastric acid from stomach parietal cells, it also plays a vital role in development progression GC. aim current study was to investigate underlying mechanism autophagy regulating GC tumorigenesis. Gastrin-17 amide (G-17) applied cell lines SGC7901 MGC-803. results showed that G-17 maintained high viability expression marker...

10.3727/096504016x14823648620870 article EN Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 2017-01-06

A novel coronavirus, SARS-CoV-2, was identified in December 2019, when the first cases were reported Wuhan, China. The once-localized outbreak has since been declared a pandemic. As of April 24, 2020, there have 2.7 million confirmed and nearly 200,000 deaths. Early warning systems using new technologies should be established to prevent or mitigate such events future.This study aimed explore possibility detecting SARS-CoV-2 2019 social media.WeChat Index is data service that shows how...

10.2196/19589 article EN cc-by JMIR mhealth and uhealth 2020-09-13

Lianhua Qingke (LH) tablets is an effective traditional Chinese medicine against various viral infections, especially in relieving coughing. However, its effects on COVID-19 are unknown.To examine the therapeutic effectiveness of LH patients with mild and common types, a randomized, multicenter, controlled study was carried out. cases were randomized to undergo routine treatment or without (4 tablets, three times day) for 14 days. The primary endpoints rate achieving clinical symptom...

10.1155/2022/8733598 article EN Evidence-based Complementary and Alternative Medicine 2022-02-10

Abstract Background Injectable poly-D,L-lactic acid (PDLLA), under the brand name of AestheFill (REGEN Biotech, Inc., Seoul, South Korea), is a biocompatible, biodegradable, and biostimulatory product utilized to correct soft tissue volume loss. Its efficacy safety have not been fully studied in large cohort. Objectives The aim study was evaluate novel dermal filler injectable, acid. Methods This an evaluator-blinded, multicenter, randomized controlled trial compare PDLLA vs hyaluronic...

10.1093/asj/sjae180 article EN Aesthetic Surgery Journal 2024-08-23

Summary Modern transportation plays a key role in the long-distance and rapid spread of SARS-CoV-2. However, little is known about transmission risk SARS-CoV-2 on confined vehicles, such as airplanes trains. Based itinerary epidemiological data COVID-19 cases close contacts among 9,265 airline passengers 291 29,335 830 high-speed trains China from December 20, 2019 to March 17, 2020, we estimated that upper bound overall attack rate was 0.60% (95% confidence interval: 0.43%-0.84%) for 0.35%...

10.1101/2020.12.21.20248383 preprint EN cc-by-nc medRxiv (Cold Spring Harbor Laboratory) 2020-12-22

Objective To investigate the effects of high-load eccentric exercise on ultrastructure autophagy and autophagy-related proteins Beclin1 LC3II / I in rats. Methods Forty-eight SD male rats were randomly divided into control group (C, n=8) (E, n=40) after adaptive training. Group E was run downhill for 90 minutes running platform, soleus muscles collected at 0, 12, 24, 48 72 hours exercise. Transmission electron microscopy used to observe ultrastructural changes skeletal muscle autophagosomes....

10.12047/j.cjap.5944.2020.064 article EN Chinese Journal of Applied Physiology 2020-07-01

Abstract With the increasing requirement of people, functions in-vehicle infotainment systems are becoming more and abundant, their security also affects safety vehicles. Therefore, it is important to evaluate IVI system. This paper proposes a evaluation framework for based on threat analyses penetration tests. By constructing data flow diagram application scenarios, analyzing threats, combing attack link diagram, combining white-box audit black-box test, we use characteristics high...

10.1088/1742-6596/2517/1/012012 article EN Journal of Physics Conference Series 2023-06-01

Essential tremor (ET), characterized by a postural and/or kinetic and primarily manifested in the upper extremities, head, other parts of body, is one most common neurological disorders.1 The traditional target for neurosurgical treatment ET, ventral intermedius nucleus (Vim) thalamus, has confirmed that chronic deep brain stimulation (DBS) an effective, standard, primary procedure ET.2 However, loss suppression due to tolerance Vim stimulation, accompanied adverse effects, such as...

10.3760/cma.j.issn.0366-6999.20122803 article EN cc-by-nc-nd Chinese Medical Journal 2013-01-20

To explore the regularity and characteristics of clinical application scalp acupuncture therapy for different types conditions so as to provide a reference practice.In present study, "head acupuncture" and"scalp were used keywords search papers academic dissertations having definite standards diagnosis therapeutic effect assessment published in journals conferences collected database China National Knowledge Internet(CNKI) from January 1 1959 December 31 2016, followed by constructing after...

10.13702/j.1000-0607.170518 article EN PubMed 2018-03-25

The scalp acupuncture therapy, an important component of the microneedle system acupuncturology, is effective in treatment multiple types diseases. In present paper, we made a comparative analysis about theoretical basis, acupoint location and main clinical indications ten academic schools scalp-acupuncture, including FANG Yun-peng's Scalp Acupuncture, JIAO Shun-fa's ZHU Ming-qing's etc. which are widely used clinic at after collecting related articles published recent 60 years from...

10.13702/j.1000-0607.201066 article EN Acupuncture Research 2021-09-25
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