- Viral Infections and Immunology Research
- Hepatitis C virus research
- Educational Systems and Policies
- Chinese history and philosophy
- Diverse Topics in Contemporary Research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Diverse Approaches in Healthcare and Education Studies
- Data-Driven Disease Surveillance
- Transportation Planning and Optimization
- Misinformation and Its Impacts
- Animal Disease Management and Epidemiology
- Respiratory viral infections research
- COVID-19 epidemiological studies
- COVID-19 diagnosis using AI
- Access Control and Trust
- T-cell and Retrovirus Studies
- HIV/AIDS drug development and treatment
- Diverse Aspects of Tourism Research
- Pneumonia and Respiratory Infections
- Folklore, Mythology, and Literature Studies
- Vietnamese History and Culture Studies
- Conferences and Exhibitions Management
- Information and Cyber Security
- Educational and Social Studies
Second Affiliated Hospital of Xi'an Jiaotong University
2013-2024
Huanggang Central Hospital
2024
Yangtze University
2024
Minzu University of China
2022
Third Affiliated Hospital of Guangzhou Medical University
2022
Guangzhou Medical University
2022
Second Affiliated Hospital of Guangzhou Medical University
2022
Zhengzhou University of Aeronautics
2020
Southeast University
2019
Xiangya Hospital Central South University
2016
Background Cirrhosis is a disease that imposes heavy burden worldwide, but its incidence varies widely by region. Therefore, we analysed data on the and mortality of cirrhosis in 204 countries territories from 1990–2019 projected development 2019–2039.
BACKGROUNDNucleos(t)ide analog (NA) has shown limited effectiveness against hepatitis B surface antigen (HBsAg) clearance in chronic (CHB) patients. AIMTo evaluate the efficacy and safety of add-on peginterferon α-2a (peg-IFN α-2a) to an ongoing NA regimen CHB METHODSIn this observational study, 195 patients with HBsAg ≤ 1500 IU/mL, e (HBeAg)-negative (including HBeAg-negative or HBeAg-positive who achieved after antiviral treatment NA) virus-deoxyribonucleic acid < 1.0 × 102 IU/mL over 1...
According to our clinical experience, cellulitis is common in summer; however, very few studies have mentioned this trend.Using Google Trends, we analyzed the monthly data of searches for "cellulitis" from 31 countries on 6 continents.Seasonality explained 34%-92% variability search volume, with peaks occurring summer months.The analyses offered new insights into epidemiology national and international scales. Clinical are needed validate Internet data.
Abstract Background & Aims The effectiveness and safety of peginterferon alpha (peg‐IFN‐α) monotherapy in inactive hepatitis B virus (HBV) carriers (IHCs) have not been fully evaluated. Methods This observational study prospectively enrolled 298 IHCs China from 2015 to 2019. Participants were given the right choose either receive peg‐IFN‐α (treatment group, n = 142) or be monitored without treatment (control 156) according their wishes. scheduled duration was 48 weeks. All participants...
Enterovirus 71 (EV71) has caused great morbidity, mortality, and use of health service in children younger than five years China. Vaccines against EV71 have been proved effective safe by recent phase 3 trials are now available The purpose this study was to evaluate the impact cost-effectiveness a national vaccination program China.Using Microsoft Excel, decision model built calculate net clinical economic outcomes compared with no birth cohort 1,000,000 Chinese followed for years. Model...
A novel coronavirus, SARS-CoV-2, was identified in December 2019, when the first cases were reported Wuhan, China. The once-localized outbreak has since been declared a pandemic. As of April 24, 2020, there have 2.7 million confirmed and nearly 200,000 deaths. Early warning systems using new technologies should be established to prevent or mitigate such events future.This study aimed explore possibility detecting SARS-CoV-2 2019 social media.WeChat Index is data service that shows how...
BACKGROUNDRegimens involving direct-acting antiviral agents (DAAs) are recommended for the treatment of infection with hepatitis C virus (HCV) genotypes 1, 2 and 3.But real-world data is still not enough, especially in Asia. AIMTo investigate efficacy safety DAA-based regimens a real-life setting China.
Abstract We plotted daily data on the frequencies of keywords related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from WeChat, a Chinese social media. Using “Feidian”, abbreviation for SARS, may detect SARS-CoV-2 outbreak in 2019 two weeks earlier. WeChat offered new approach early disease outbreaks.
As an emerging mountain vacation tourism product, ski is becoming increasingly important in the domestic market. theory for studying quality of consumer experience, perceived value has been widely employed research recent years, and improving experience become focus competition among destinations. Taking tourists Chongli District Zhangjiakou as example, 305 valid questionnaires were collected by using online offline methods. Based on value, this paper adopted principal component analysis...
To assess whether breastfeeding duration can affect risk of severe hand, foot and mouth disease (HFMD) later in childhood, we retrospectively analyzed demographic, environmental data on 603 children with HFMD 1036 mild HFMD. Multivariate analysis showed that for 6-12 months significantly reduced the HFMD, as did >12 months.
Hepatitis C virus (HCV) is closely associated with insulin resistance (IS), acting primarily by interfering signaling pathways, increasing cytokine-mediated (tumor necrosis factor α, interleukin 6) inflammatory responses and enhancing oxidative stress. In the receptor substrate (IRS) one of key regulatory factors. The present study constructed gene sub‑networks specific for IRS1 IRS2 in Huh7 cells HCV‑infected (HCV‑Huh7) using linear programming a decomposition algorithm, investigated...
T lymphocytes play a pivotal role in resolving hepatitis B virus infection. This study aimed to investigate the dynamics of peripheral blood lymphocyte subsets during peginterferon alpha (peg-IFN-α) therapy and their association with surface antigen (HBsAg) clearance inactive HBsAg carriers (IHCs). prospective observational enrolled 197 IHCs treated peg-IFNα-2a/2b for 48 weeks followed 24 (treatment group), 221 who were regularly monitored 72 without treatment (IHC control group). Peripheral...
In the usage control of information resources with access matrix as core idea, rights are generally permanently endowed to subject. Based on idea temporary authorization, strategy for based UCONABC model is studied and subject reliability introduced into (usage authorizations, obligations, conditions) decision-making factor authorization in resources. Through analysis typical structural relations among subjects, evaluation method relational distance attribute designed; this basis, a new...
Travelers' automobile use habit is a key to influence their travel mode choice behavior under the impacts of congestion pricing. To address complex preference combing travelers' heterogeneity, stated survey that divided participants into more- and less-habitual travelers conducted in Beijing inner districts. Four mixed logit models are proposed estimate impact pricing on commuting non-commuting behavior. Model estimation results illustrate similarities dissimilarities between travelers. This...