A5100765530- Particle Dynamics in Fluid Flows
- Semiconductor materials and devices
- MicroRNA in disease regulation
- Advanced Drug Delivery Systems
- Ferroptosis and cancer prognosis
- Drug Solubulity and Delivery Systems
- Epigenetics and DNA Methylation
- Protein purification and stability
- RNA Interference and Gene Delivery
- Aerosol Filtration and Electrostatic Precipitation
- Wind and Air Flow Studies
- Nuclear reactor physics and engineering
- Microbial Metabolites in Food Biotechnology
- Chemotherapy-induced cardiotoxicity and mitigation
- Cancer-related gene regulation
- High-Voltage Power Transmission Systems
- Cancer, Hypoxia, and Metabolism
- RNA modifications and cancer
- Ginseng Biological Effects and Applications
- Advancements in Semiconductor Devices and Circuit Design
- Cancer-related molecular mechanisms research
- Immunotherapy and Immune Responses
- Advancements in Transdermal Drug Delivery
- Metallurgical Processes and Thermodynamics
- Heat Transfer and Optimization
Northeast Petroleum University
2025
Jiangsu Academy of Agricultural Sciences
2023-2024
National Taiwan University
2022-2024
Donghua University
2022-2024
Renmin University of China
2024
Methodist Hospital
2023-2024
Xian Central Hospital
2016-2023
Methodist Hospital
2023
West China Second University Hospital of Sichuan University
2023
Sichuan University
2022-2023
As a newly identified type of programmed cell death, cuproptosis may have an impact on cancer development, including clear renal carcinoma (ccRCC). Herein, we first noticed that the expression levels regulators exhibited tight correlation with clinicopathological characteristics ccRCC. The cuproptosis-sensitive sub-type (CSS), classified via consensus clustering analysis, harbored higher overall survival rate compared to cuproptosis-resistant (CRS), which resulted from differential...
The discovery of room-temperature ferromagnetism in van der Waals (vdW) materials opens new avenues for exploring low-dimensional magnetism and its applications spintronics. Recently, the observation topological Hall effect vdW ferromagnet Fe3GaTe2 suggests possible existence skyrmions, yet skyrmions have not been directly observed. In this study, real-space imaging was employed to investigate domain evolution labyrinth skyrmion structure. First, Néel-type can be created at room temperature....
Abstract This study mainly explored the role of nicorandil in regulating ferroptosis and alleviating septic cardiomyopathy through toll-like receptor (TLR) 4/solute carrier family 7 member 11 (SLC7A11) signaling pathway. Twenty-four male SD rats were randomly divided into control, Nic (nicorandil), LPS (lipopolysaccharide), + groups given echocardiography. A detection kit was applied to measure levels lactic dehydrogenase (LDH), cardiac troponin I (cTnI), creatine kinase-MB (CK-MB); HE...
The dynamic stress analysis of a strip plate with elliptical holes under the action an incident SH wave was performed using complex function method and successive mirror method. Firstly, plane coordinate system elliptic established by variable integral transformation hole field were expansion Then, relation between argument angle any point on edge ellipse vertical line axis established. Using boundary conditions to solve unknown coefficients in equation, finally, equation simplified linear...
Two new melampolide-type sesquiterpene lactones, 8β-epoxyangeloyloxy-9α-ethoxy-14-oxo-acanthospermolide (1) and 8β-angeloyloxy-9α-ethoxy-14-oxo-acanthospermolide (2), were isolated from the leaves of yacon [Smallanthus sonchifolia (POEPP. et ENDL.) H. Robinson] along with eleven known melampolides, allo-schkuhriolide (3), enhydrin (4), polymatin A (5), fluctuanin (6), 8β-angeloyloxy-9α-acetoxy-14-oxo-acanthospermolide (7), 8β-angeloyloxy-14-oxo-acanthospermolide (8),...
Smallanthus sonchifolius (Yacon, Asteraceae) was originally cultivated in South America and used food traditional medicine by Andean inhabitants. Yacon is potentially beneficial for the management of diabetes composed fructooligosaccharides, proteins, minerals phenolic compounds. The aim this study to investigate hypoglycemic effect tuber extract (YTE) its constituent, chlorogenic acid (CGA), streptozotocin (STZ)-induced diabetic rats. In study, a HPLC method developed simultaneous...
Abstract Studies have found that miR‐665 acted as a tumor suppressor or an oncogene in different malignancies. expression was elevated gastric adenocarcinoma tissues; however, its role and mechanism this disease are not fully clarified. The of target gene detected human tissues cells. Moreover, we analyzed the effects on proliferation, migration, epithelial–mesenchymal transition (EMT) cells well growth vivo. mechanisms were investigated by using molecular biology techniques. We upregulated...
Abstract The long non-coding RNA DUXAP10 has been involved in the development, progression, and metastasis several human cancers, but its biological function underlying mechanism hepatocellular carcinoma (HCC) still undetermined. present study was proposed to explore effect of on growth HCC cells potential mechanisms involved. results showed that is dramatically elevated tumor tissues cell lines. Knockdown by si-RNA significantly inhibited viability, proliferation induce apoptosis line....
The high-temperature particles produced by air gouging processes are common pollutants in cleaning workshops, which could endanger workers’ health. In this research, a two-way coupled Eulerian-Lagrangian method based on discrete phase modelling (DPM) was used to investigate the transport characteristics of generated from processes. particle group movement divided into core zone and boundary zone, kinetic mechanism different zones analysed. results show more susceptible vortex entrainment...
We screened the pharmacological effects of a 50% ethanol extract Yacon tubers and leaves on spermatogenesis in rats. As result, we found that tuber extracts increased sperm number serum testosterone level It has been reported crude contain phenolic acids, such as, chlorogenic acid, ferulic acid caffeic by HPLC/MS analysis. were interested contributions made particularly to spermatogenic activity. After administering or rats for 5 weeks, numbers epididymis 34% 20%, respectively. also...
Gastric cancer (GC) is one of the most frequent epithelial malignancies worldwide. The gastrointestinal (GI) peptide gastrin an important regulator secretion and release gastric acid from stomach parietal cells, it also plays a vital role in development progression GC. aim current study was to investigate underlying mechanism autophagy regulating GC tumorigenesis. Gastrin-17 amide (G-17) applied cell lines SGC7901 MGC-803. results showed that G-17 maintained high viability expression marker...
Alcohol abuse and chronic alcohol consumption are major causes of alcoholic liver disease worldwide, particularly alcohol-induced hepatic fibrosis (AHF). Liver is an important public health concern because its high morbidity mortality. The present study examined the mechanisms effects phosphodiesterase III inhibitor cilostazol on AHF. Rats received infusions via gavage to induce were treated with colchicine (positive control) or cilostazol. serum dehydrogenase (ADH) acetaldehyde (ALDH)...
The programmed cell death 4 (PDCD4) tumor-suppressor gene regulates apoptosis, protein translation, signal transduction, and induction of mediators inflammation. However, the mechanism by which PDCD4 is down-regulated tumor growth remains elusive. In this study, we showed that in glioma cells acts as a suppressor. Based on TCGA data, confirmed AKT2, but not AKT1 or AKT3, interacts with PDCD4, thus leading to suppression cells. Moreover, analysis suggested expression IL-5, CCL-5, VEGF, CXCL10...
Xtacking™ is a novel 3D (three-dimensional) NAND flash architecture, in which memory cells and peripheral circuits are bonded by millions of pairs small-pitch metal vias. Consequently, its bonding interface reliability attracts great interest. In this paper, we conducted test both structure level product level. test, the layer showed stable electrical properties after ultra-long time thermal or humidity stress (e.g., 7000hrs), much longer than common industry requirement 1000hrs)....