Young-Ran Lee

ORCID: 0000-0001-8696-5513
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About
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Research Areas
  • Flowering Plant Growth and Cultivation
  • Powdery Mildew Fungal Diseases
  • Plant and animal studies
  • Ecology and Conservation Studies
  • Education and Learning Interventions
  • Educational Systems and Policies
  • Immunotherapy and Immune Responses
  • Psychosocial Factors Impacting Youth
  • Diverse Approaches in Healthcare and Education Studies
  • Health and Wellbeing Research
  • Cryptography and Data Security
  • Plant Physiology and Cultivation Studies
  • Healthcare Education and Workforce Issues
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immune Response and Inflammation
  • Security in Wireless Sensor Networks
  • RNA Interference and Gene Delivery
  • Advanced Authentication Protocols Security
  • Adipose Tissue and Metabolism
  • Plant tissue culture and regeneration
  • Bacillus and Francisella bacterial research
  • Hair Growth and Disorders
  • Identification and Quantification in Food
  • Immune cells in cancer

Korea Institute of Ceramic Engineering and Technology
2021-2025

Korea Institute of Ocean Science and Technology
2025

Korea National Institute of Health
2014-2024

Seoul Women's College of Nursing
2011-2023

Osan University
2023

Biocera (South Korea)
2021-2023

Chungbuk National University
2005-2022

Sun Moon University
2005-2022

Convergence
2022

Rural Development Administration
2022

Introduction The inadequate efficacy of the Bacillus Calmette–Guérin (BCG) vaccine against adult pulmonary tuberculosis (TB) necessitates development new and effective vaccines. Human adenovirus serotype 5 (Ad5), which induces T-cell response, is a widely used viral vector. In this study, we aimed to evaluate multi-antigenic recombinant Ad5 vectored determine optimal immunization route for enhanced immune response Mycobacterium . Methods We constructed expressing four antigens...

10.3389/fmicb.2025.1492268 article EN cc-by Frontiers in Microbiology 2025-01-24

Microplastics are ubiquitous environmental pollutants in terrestrial, marine, and atmospheric ecosystems. Plastic inputs into the atmosphere occur through weathering or abrasion, dispersing microplastics globally, which can enter animals' respiratory systems inhalation. We analyzed lung tissues for first time intestinal contents of 11 dead finless porpoises (Neophocaena asiaeorientalis) to assess intake from prey sources. The contained average concentrations 0.14 ± 0.11 MPs/g 0.35 0.36...

10.1021/acs.est.4c10640 article EN Environmental Science & Technology 2025-03-25

We present a new identity based authenticated key agreement protocol from pairings satisfying the required security attributes. The of our is on bilinear Diffie- Hellman assumption.

10.4134/ckms.2005.20.4.849 article EN Communications of the Korean Mathematical Society 2005-10-01

Metals are commonly used in cosmetic products for blocking ultraviolet light or coloring pigments; however, some metals exceed specific concentrations and can cause serious safety issues such as skin troubles allergies. It is, therefore, important to measure the exact amount of metal products. However, cosmetics that contain many organic inorganic materials like oils, polymers, waxes, polyols, surfactants, metallic powders difficult analyze due matrix effect. In this study, we developed...

10.1080/00032710903325781 article EN Analytical Letters 2010-01-12

Previously we showed that biodegradable nanoparticles containing poly-IC or CpG oligodeoxynucleotide (ODN) together with ovalbumin (OVA) were efficient at inducing MHC-restricted presentation of OVA peptides in dendritic cells.The CTL-inducing activities the examined present study.Nanoparticles ODN prepared using polymer poly(D,L-lactic acid-co-glycolic acid), and then opsonized mouse IgG.The injected into tail vein mice, 7 days later OVA-specific CTL measured an vivo assay.Immunization mice...

10.4110/in.2013.13.1.30 article EN Immune Network 2013-01-01

The excessive production of reactive oxygen species (ROS) causes harmful effects, including biomolecular damage and inflammation. ROS due to ultraviolet rays, blue light, fine dust harm the skin, causing urban-related aging. Therefore, a strong antioxidant that relieves oxidative stress in skin removes is required. Idebenone (IB) powerful but poorly soluble thus has low solubility water, resulting bioavailability. In this study, IB-loaded nanoparticles (IB@NPs) were synthesized by loading IB...

10.3390/pharmaceutics14030521 article EN cc-by Pharmaceutics 2022-02-26

The influenza virus poses a global health burden. Currently, an annual vaccine is used to reduce virus-associated morbidity and mortality. Most vaccines have been developed elicit neutralizing Abs against virus. These primarily target immunodominant epitopes derived from hemagglutinin (HA) or neuraminidase (NA) of the incorporated in vaccines. However, HA NA are highly variable proteins that prone antigenic changes, which can efficacy. Therefore, it essential develop universal conserved...

10.4110/in.2024.24.e19 article EN Immune Network 2024-01-01

Abstract APCs, like T cells, are affected by calcineurin inhibitors. In this study, we show that inhibitors efficiently block MHC-restricted exogenous Ag presentation in vivo. Mice were injected with clinical doses of tacrolimus (FK-506) followed soluble OVA, and dendritic cells (DCs) isolated from lymph nodes spleens. The efficacy OVA peptide DCs was evaluated using OVA-specific CD8 CD4 cells. Tacrolimus inhibited both class I- II-restricted DC to also peritoneal macrophages mice OVA....

10.4049/jimmunol.179.9.5711 article EN The Journal of Immunology 2007-11-01

Nanoparticles (NPs) prepared from biodegradable polymers, such as poly (D,L-lactic acid-co-glycolic acid) (PLGA), have been studied vehicles for the delivery of antigens to phagocytes. This paper describes preparation antigen-loaded PLGA-NPs efficient cross-priming.NPs containing a similar amount ovalbumin (OVA) but different sizes were produced using micromixer-based W/O/W solvent evaporation procedure, and efficiency NPs induce cross-presentation OVA peptides examined in dendritic cells...

10.4110/in.2011.11.3.163 article EN Immune Network 2011-01-01

Purpose: This study was conducted to describe stress, stress coping, and school adaptation according Myers-Briggs type indicator(MBTI) personality in freshmen nursing students. Methods: a cross sectional survey the data collected from 267 students by means of self reported questionnaires March 3 30, 2012. Collected were analyzed on SPSS win 18.0. Results: 16 types all seen this participants. There no significant differences 4 functions temperaments MBTI. Conclusion: Nursing show various we...

10.5977/jkasne.2013.19.2.172 article EN The Journal of Korean Academic Society of Nursing Education 2013-05-28

Mycobacterium tuberculosis was responsible for 1.3 million deaths worldwide in 2022. Bacillus Calmette-Guérin (BCG) is the only licensed vaccine against (TB); however, it has limited protective efficacy adults. In this study, we constructed a recombinant vaccinia virus expressing Ag85B from M. using novel attenuated (KVAC103). We then analyzed immunogenicity of prime-boost inoculation strategies KVAC103 (rKVAC85B) compared to BCG. both rKVAC85B and BCG prime-rKVAC85B boost regimens, induced...

10.20944/preprints202403.0351.v1 preprint EN 2024-03-06

Purpose: This study was performed to explore the effects of an admission-education program on knowledge, self-efficacy, self-care and glucose control in type 2 diabetes patients. Method: A single group pre-post test design used. Twenty-one patients participated this during 6 days which consisted education practice about exercise, diet, prevention complications. Variables at baseline, 3 months, months were measured. Results: Knowledge level, level self-efficacy significantly increased over...

10.5977/jkasne.2008.14.1.012 article EN The Journal of Korean Academic Society of Nursing Education 2008-06-30
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