A5100360915- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Virus-based gene therapy research
- Plant-Microbe Interactions and Immunity
- Plant Pathogenic Bacteria Studies
- Herpesvirus Infections and Treatments
- Food Quality and Safety Studies
- Animal Disease Management and Epidemiology
- Influenza Virus Research Studies
- Hepatitis Viruses Studies and Epidemiology
- Ecology and Conservation Studies
- Probiotics and Fermented Foods
- Plant and Fungal Interactions Research
- Plant Virus Research Studies
- Legume Nitrogen Fixing Symbiosis
- Agriculture, Soil, Plant Science
- Respiratory viral infections research
- Viral Infections and Immunology Research
- Veterinary medicine and infectious diseases
- Gut microbiota and health
- Fungal Biology and Applications
- Diverse Approaches in Healthcare and Education Studies
- Microbial infections and disease research
- Plant Pathogens and Fungal Diseases
- Liver Disease and Transplantation
Kyung Hee University
2015-2025
Korea Electric Power Corporation (South Korea)
2025
Korea Disease Control and Prevention Agency
2014-2025
Konkuk University
2015-2024
Inha University
2012-2024
National Cancer Center
2024
Korea Institute for Industrial Economics and Trade
2023
Seoul National University
2023
Soonchunhyang University
2020-2022
Konkuk University Medical Center
2009-2022
Summary Disturbances caused by timber harvesting have critical long‐term effects on the forest soil microbiota and alter fundamental ecosystem services provided these communities. This study assessed of organic matter removal compaction microbial community structures in different horizons 13 years after at productivity site Skulow Lake, British Columbia. A harvested stand was compared with an unmanaged stand. Ribosomal intergenic spacer profiles bacteria, archaea eukarya indicated...
Problems can arise when vaccines and wild strains of a chicken herpesvirus recombine.
The transferred microbiota from mother to baby constitutes the initial infant gastrointestinal and has an important influence on development health of infants in human. However, reproductive tract avian species its inheritance have rarely been studied. We aimed characterize microbial community chicken determine origin embryo gut microbiota. Microbiota four different portions oviduct were determined using 16S rRNA metagenomic approach with IonTorrent platform. Additionally, we analyzed hen's...
The oral microbiome, which is closely associated with many diseases, and the resident pathogenic bacteria, can be transferred by close physical contact, are important public health considerations. Although dog most common companion animal, composition of canine may include human its relationship that their owners unclear. In this study, 16S rDNA pyrosequencing was used to compare microbiomes 10 dogs identify zoonotic pathogens. Pyrosequencing revealed 246 operational taxonomic units in...
Resveratrol has been clinically shown to possess a number of human health benefits. As result, many attempts have made engineer resveratrol production in major cereal grains but largely unsuccessful. In this study, we report the creation transgenic rice plant that accumulates 1.9 µg resveratrol/g its grain, surpassing previously reported anti-metabolic syndrome activity through synergistic interaction between and endogenous properties rice. Consumption our resveratrol-enriched significantly...
Genes involved in a viral resistance response common bean ( Phaseolus vulgaris cv. Othello) were identified by inoculating geminivirus reporter Bean dwarf mosaic virus expressing the green fluorescent protein), extracting RNA from tissue undergoing defense response, and amplifying sequences with degenerate R gene primers. One such (a TIR-NBS-LRR gene, RT4-4 ) was selected for functional analysis which transgenic Nicotiana benthamiana generated screened to range of viruses. This revealed that...
The rice pathogen recognition receptor, XA21, confers resistance to Xanthomonas oryzae pv. strains producing the type one system-secreted molecule, AvrXA21. X. requires a regulatory two-component system (TCS) called RaxRH regulate expression of eight rax (required for AvrXA21 activity) genes and sense population cell density. To identify other key components in this critical circuit, we assayed proteins expressed raxR gene knockout strain. This survey led identification phoP encoding...
Water deficiencies are one of the most serious challenges to crop productivity. To improve our understanding soil moisture stress, we performed RNA-Seq analysis using roots from 4-week-old rice seedlings grown in that had been subjected drought conditions for 2-3 d. In all, 1,098 genes were up-regulated response stress 3 d, which causes severe damage root development after recovery, unlikely 2 Comparison with previous transcriptome data produced condition indicated more than 68% candidate...
Shikonin (SKN), a highly liposoluble naphthoquinone pigment isolated from the roots of Lithospermum erythrorhizon , is known to exert antibacterial, wound-healing, anti-inflammatory, antithrombotic, and antitumor effects. The aim this study was examine SKN antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). analyzed in combination with membrane-permeabilizing agents Tris Triton X-100, ATPase inhibitors sodium azide N,N ′-dicyclohexylcarbodiimide, S. -derived...
WRKY proteins play important roles in transcriptional reprogramming plants response to various stresses including pathogen attack. In this study, we functionally characterized a rice gene, OsWRKY67, whose expression is upregulated against challenges. Activation of OsWRKY67 by T-DNA tagging significantly improved the resistance two pathogens, Magnaporthe oryzae and Xanthomonas pv. (Xoo). Reactive oxygen species (ROS) rapidly accumulated activation mutant lines elicitor treatment, compared...
Cinnamoyl-CoA reductase (CCR) is the first committed enzyme in monolignol pathway for lignin biosynthesis and catalyzes conversion of hydroxycinnamoyl-CoAs into hydroxycinnamaldehydes. In rice genome, 33 genes are annotated as CCR CCR-like genes, collectively called OsCCRs. To elucidate functions OsCCRs, their phylogenetic relationships, expression patterns at transcription levels biochemical characteristics were thoroughly analyzed. Of 24 them encoded polypeptides lengths similar to those...
Data concerning the human microbiota composition during Clostridioides (Clostridium) difficile infection (CDI) using next-generation sequencing are still limited. We aimed to confirm key features indicating tcdB positive patients and compare between subgroups based on toxin gene load (tcdB gene) presence of significant diarrhea. Ninety-nine fecal samples from 79 20 controls were analyzed 16S rRNA sequencing. Chao1 index for alpha diversity calculated principal coordinate analysis was...
By employing a combination of the extended technology acceptance model and technology-organization-environment framework, this study examines influential factors in digital advertising policy by Korean out home (OOH) adverting firms undergoing transformation. To end, unique data from national survey 1,001 OOH firms, such firms’ policy. The results hierarchical regression analysis reveal that two key variables—perceived usefulness perceived ease use—from positively influence acceptance....
Plants are susceptible to infection by various pathogens with high epidemic potential. Xanthomonas oryzae pv. (Xoo) causes bacterial blight in rice, one of the most significant diseases both temperate and tropical regions. In this study, we report identification characterization OsWRKY26, a sucrose-inducible transcription factor, that plays role plant defense responses following Xoo infection. We found mutant plants defective OsWRKY26 showed enhanced response specifically Xoo, indicating...
Introduction The inadequate efficacy of the Bacillus Calmette–Guérin (BCG) vaccine against adult pulmonary tuberculosis (TB) necessitates development new and effective vaccines. Human adenovirus serotype 5 (Ad5), which induces T-cell response, is a widely used viral vector. In this study, we aimed to evaluate multi-antigenic recombinant Ad5 vectored determine optimal immunization route for enhanced immune response Mycobacterium . Methods We constructed expressing four antigens...
Infectious laryngotracheitis is an acute viral respiratory disease of chickens with a worldwide distribution. Sensitive detection the causative herpesvirus particularly important because it can persist in host at very low copy number and be transmitted to other birds. Quantification genome also useful for clinical investigations experimental studies. In study presented here, quantitative polymerase chain reaction (qPCR) assay was developed using SYBR Green chemistry gene UL15a detect...
In contrast to the RNA viruses, genome of large DNA viruses such as herpesviruses have been considered be relatively stable. Intra-specific recombination has proposed an important, but underestimated, driving force in herpesvirus evolution. Recently, two distinct field strains infectious laryngotracheitis virus (ILTV) shown arisen from independent events between different commercial ILTV vaccines. this study we sequenced genomes additional and also utilized other recently updated complete...
In 2014, the highly pathogenic avian influenza (HPAI) virus H5N8 triggered outbreaks in wild birds and poultry farms South Korea. present study, we investigated pathogenicity of HPAI virus, belonging to clade 2.3.4.4, different species poultry. For this, examined clinical signs viral shedding levels following intranasal inoculation 3-week-old commercial layer chickens quails, 10-week-old Korean native chickens, 8-week-old Muscovy ducks. Intranasal with 10(6.0) viruses at 50% egg-infective...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of disease-19 (COVID-19). More than 143 million cases COVID-19 have been reported to date, with global death rate at 2.13%. Currently, there are no licensed therapeutics for controlling SARS-CoV-2 infection. The antiviral effects heme oxygenase-1 (HO-1), a cytoprotective enzyme that inhibits inflammatory response and reduces oxidative stress, investigated in several viral infections. To confirm whether HO-1...