A5053894227- Pharmaceutical Practices and Patient Outcomes
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical industry and healthcare
- Pharmaceutical Economics and Policy
- Opioid Use Disorder Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare cost, quality, practices
- Healthcare Policy and Management
- Pain Management and Opioid Use
- Primary Care and Health Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Geriatric Care and Nursing Homes
- Emergency and Acute Care Studies
- Diabetes Treatment and Management
- Medication Adherence and Compliance
- Dementia and Cognitive Impairment Research
- Health and Medical Research Impacts
- Hemodynamic Monitoring and Therapy
- Biosimilars and Bioanalytical Methods
- Patient Satisfaction in Healthcare
- Substance Abuse Treatment and Outcomes
- Intensive Care Unit Cognitive Disorders
- Diabetes Management and Research
- Prenatal Substance Exposure Effects
VA Pittsburgh Healthcare System
2024-2025
University of Pittsburgh
2015-2025
Harvard University
2020-2024
Beth Israel Deaconess Medical Center
2019-2024
University of Pittsburgh Medical Center
2014-2024
Job Performance Systems (United States)
2023
San Francisco VA Medical Center
2019-2023
Tallinn University
2023
The Salvation Army China
2023
Deaconess Hospital
2020-2021
Importance In 2023, the American Heart Association (AHA) developed Predicting Risk of Cardiovascular Disease Events (PREVENT) equations to estimate 10-year risk atherosclerotic cardiovascular disease (ASCVD), as an update 2013 pooled cohort (PCEs). The PREVENT were derived from contemporary cohorts and removed race added variables for kidney function statin use. Objective To compare national estimates ASCVD using PCEs how these affect recommendations primary prevention therapy. Design,...
This cross-sectional study examines patterns of use direct oral anticoagulants and their association with Medicare spending.
With Alzheimer Disease and Mild Cognitive ImpairmentIn June 2021, the US Food Drug Administration (FDA) granted accelerated approval for aducanumab to treat patients with mild cognitive impairment (MCI) or dementia due disease (AD), despite limited evidence of clinical benefit.The 2 phase 3 trials aducanumab, EMERGE ENGAGE, were stopped prematurely based on prespecified futility thresholds. 1 Both also showed an increased risk adverse events including microhemorrhages vasogenic brain edema,...
Importance Asymptomatic blood pressure (BP) elevations are common in hospitalized older adults, and widespread heterogeneity the clinical management of elevated inpatient BPs exists. Objective To examine association intensive treatment with in-hospital outcomes adults for noncardiac conditions. Design, Setting, Participants This retrospective cohort study examined Veterans Health Administration data between October 1, 2015, December 31, 2017, patients aged 65 years or noncardiovascular...
Importance US Food and Drug Administration–approved medications for alcohol use disorder (MAUD) are significantly underused. Hospitalizations may provide an unmet opportunity to initiate MAUD, but few studies have examined clinical outcomes of patients who these at hospital discharge. Objective To investigate the association between discharge MAUD initiation 30-day posthospitalization outcomes. Design, Setting, Participants This cohort study was conducted among with Medicare Part D had...
This study uses National Health and Nutrition Examination Survey data to examine national trends in preventive aspirin use among populations at low high atherosclerotic cardiovascular disease (ASCVD) risk with existing ASCVD.
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast JAMA+ AI Journals Network Open Cardiology Dermatology Health Forum Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...
Guideline-based management of cardiovascular disease often involves prescribing multiple medications, which contributes to polypharmacy and risk for adverse drug events in older adults. Deprescribing is a potential strategy mitigate these risks. We sought characterize compare clinician perspectives regarding deprescribing medications across three specialties. National cross-sectional survey. Ambulatory. Random sample geriatricians, general internists, cardiologists from the American College...
Transient elevations of blood pressure (BP) are common in hospitalized older adults and frequently lead practitioners to prescribe more intensive antihypertensive regimens at hospital discharge than the patients were using before hospitalization.To investigate association between intensification clinical outcomes after discharge.In this retrospective cohort study, 65 years with hypertension who Veterans Health Administration national health system facilities from January 1, 2011, December...
The use of pharmacogenetics and pharmacogenomics in the drug development process, assessment such data submitted to regulatory agencies by industry, has generated significant enthusiasm as well important reservations within scientific medical communities. This situation arisen because increasing number exploratory confirmatory investigations into variations RNA expression patterns DNA sequences being conducted preclinical clinical phases development, uncertainty surrounding acceptance these...
Although physicians learn about new medical technologies from their peers, the magnitude and source of peer influence is unknown. We estimate effect adoption three first-in-class medications (dabigatran, sitigliptin, aliskiren) on physicians' own those medications. included 11,958 in Pennsylvania prescribing anticoagulant, antidiabetic, antihypertensive constructed 4 types networks based shared Medicare Medicaid patients, group affiliation, hospital school/residency training. Instrumental...
Dementia is associated with higher healthcare expenditures, in large part due to increased hospitalization rates relative patients without dementia. Data on contemporary trends the incidence and outcomes of potentially preventable hospitalizations dementia are lacking.Retrospective cohort study using National Inpatient Sample from 2012 2016.U.S. acute care hospitals.A total 1,843,632 unique older adults (aged ≥65 years) diagnosed dementia.Annual for all causes conditions including ambulatory...
LettersAugust 2023Pharmacologic Treatment Initiation Among Medicare Beneficiaries Hospitalized With Alcohol Use DisorderCorrection(s) for this article:Corrections29 Aug 2023Correction: Pharmacologic DisorderFREEEden Y. Bernstein, MD, Travis P. Baggett, MPH, Shrunjal Trivedi, Shoshana J. Herzig, Timothy S. Anderson, MASEden MDDivision of General Internal Medicine, Massachusetts Hospital, and Harvard Medical School, Boston, Massachusetts, MPHDivision Hospital; School; Institute Research,...
This study examines purchasing patterns regarding oral decongestants, concerns about their efficacy, and the need for timelier postmarket evaluation.
The use of many services is lower in Medicare Advantage (MA) compared with traditional Medicare, generating cost savings for insurers, whereas the quality ambulatory higher. This study examined role selective contracting providers achieving these outcomes, focusing on primary care physicians. Assessing physician costliness based gap between observed and predicted costs their patients, we found that average MA networks was $433 less costly per patient (2.9 percent baseline) regional mean,...
Importance Guidelines recommend deprescribing opioids in older adults due to risk of adverse effects, yet little is known about patient-clinician opioid conversations. Objective To understand the experiences and primary care practitioners (PCPs) with using for chronic pain discussing deprescribing. Design, Setting, Participants This qualitative study conducted semistructured individual interviews 18 PCPs 29 65 years or prescribed between September 15, 2022, April 26, 2023, at a Boston-based...
Abstract Enrollment in Medicare Advantage (MA) plans rose to over 50% of eligible patients 2023. Payments MA incorporate risk scores that are largely based on patient diagnoses from the prior year, which incentivizes code more intensively. We estimated coding inflation rates for individual contracts using a method allows differential selection into health. illustrate data and health conditions most recent year available, 2014. This approach could also be used beginning 2022, when...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast JAMA+ AI Journals Network Open Cardiology Dermatology Health Forum Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...