A5102873784- Pregnancy and preeclampsia studies
- Neonatal and Maternal Infections
- Preterm Birth and Chorioamnionitis
- Pregnancy and Medication Impact
- Streptococcal Infections and Treatments
- Maternal and fetal healthcare
- Uterine Myomas and Treatments
- Criminal Law and Policy
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Sepsis Diagnosis and Treatment
- Neonatal Respiratory Health Research
- Intestinal and Peritoneal Adhesions
- Hernia repair and management
- Cardiovascular Issues in Pregnancy
- Prenatal Screening and Diagnostics
- Pneumonia and Respiratory Infections
- Congenital Anomalies and Fetal Surgery
- Law and Political Science
- Birth, Development, and Health
- Congenital Diaphragmatic Hernia Studies
- Urological Disorders and Treatments
- Mesenchymal stem cell research
- Urinary and Genital Oncology Studies
- Muscle and Compartmental Disorders
Yonsei University
2011-2025
Seoul National University Bundang Hospital
2025
Wonju Severance Christian Hospital
2019-2022
Catholic University of Daegu
2019-2020
Inje University Sanggye Paik Hospital
2015-2020
Gyeongsangnam-do Agricultural Research and Extension Services
2017
Seoul National University
2016
Orthopedic One
2015
Kangwon National University
1998
To investigate the risk factors for vaginal infections and antimicrobial susceptibilities of microorganisms among women who experienced preterm birth (PTB), we compared prevalence between labor (PTL) without delivery spontaneous PTB.Vaginal swab specimens from 126 pregnant PTL were tested group B streptococcus (GBS), Mycoplasma hominis, genitalium, Ureaplasma urealyticum, Chlamydia trachomatis, Trichomonas vaginalis, Neisseria gonorrhoeae, Treponema pallidum, herpes simplex virus (HSV) I II,...
Intranasal delivery of mesenchymal stem cells (MSCs) to the olfactory bulb is a promising approach for treating injury. Additionally, using homing phenomenon MSCs may be clinically applicable developing therapeutic cell carriers. Herein, superparamagnetic iron oxide nanoparticles (SPIONs) and permanent magnet, we demonstrated an enhanced effect in model. Superparamagnetic with rhodamine B (IRBs) had diameter 5.22 ± 0.9 nm ζ-potential +15.2 0.3 mV. IRB concentration 15 µg/mL was injected...
Abstract Background Carbapenems are broad spectrum antibiotics widely used for treatment of various infectious disease such as pneumonia, sepsis, and urinary tract infection. have been linked to a possible drug interaction which can lead subtherapeutic levels valproate increase the risk patients experiencing seizures. In this study, we reviewed cases concomitant use valproic acid carbapenems, investigated impact drug-drug interactions effects. Methods The electronic medical records treated...
Purpose: Recently, obstetric massive transfusion protocols have shifted toward early intervention.This study aimed to develop a prediction model for of ≥5 units packed red blood cells (PRBCs) during cesarean section in women with placenta previa. Materials and Methods:We conducted cohort including 287 previa who delivered between September 2011 April 2018.Univariate multivariate logistic regression analyses were used test the association clinical factors, ultrasound transfusion.For external...
Although group B Streptococcus (GBS) colonization rate among pregnant Korean women is lower than that from many Western countries, recent data show an upward trend. We investigated epidemiological changes in GBS terms of rate, antimicrobial susceptibility, serotype, and resistance genotype.Vaginal anorectal swab specimens 379 were cultured on Strep Carrot Broth with Detect (Hardy Diagnostics, USA), selective Todd-Hewitt broth (Becton Dickinson, Granada agar plate medium Dickinson). The...
αKlotho is a type 1 transmembrane anti-aging protein. αKlotho-deficient mice have premature aging phenotypes and an imbalance of ion homeostasis including Ca2+ phosphate. Soluble known to regulate multiple channels growth factor-mediated phosphoinositide-3-kinase (PI3K) signaling. Store-operated entry (SOCE) mediated by pore-forming subunit Orai1 ER sensor STIM1 ubiquitous influx mechanism has been implicated in diseases. However, it currently unknown whether soluble regulates Orai1-mediated...
Serum creatinine level (SCr) typically decreases during pregnancy due to physiologic glomerular hyperfiltration. Therefore, the clinical practice of estimated filtration rate (eGFR) based on SCr concentrations might be inapplicable pregnant women with kidney disease since it does not take into account pregnancy-related biological changes. We integrated Wonju Severance Christian Hospital (WSCH)-based findings and prior knowledge from big data reveal relationship between abnormal but hidden...
Sarcopenia is defined as an age-related loss of skeletal muscle and associated with several health disorders. Causes sarcopenia, which included physical inactivity, alcohol, dietary habits, smoking, have been researched. The present study was undertaken to examine the association between reproductive span sarcopenia in Korean women. Data obtained from 2008 2011 Korea National Health Nutrition Examination Surveys (KNHANES) were analyzed. We based on cut-off values Foundation for Institutes...
Toll-like receptor 4 (TLR-4) is the major used for recognition of specific gram negative bacteria by host immune system. The role TLR-4 has been revealed in preterm parturition. This study aims to demonstrate immunohistochemical expression with regard histological layers and anatomical regions human fetal membranes.Fetal membranes were obtained from uterine fundus low segment. Immunohistochemical staining hematoxylin eosin stain performed.The chorion expressed significantly higher levels...
Purpose:The prevalence of Group B Streptococcus (GBS) colonization in pregnant Korean women is increasing; however, nationwide studies are lacking.Therefore, we aimed to analyze regional rates and antimicrobial susceptibility for GBS through a survey.Materials Methods: From January 2018 December 2020, data from the Seoul Clinical Laboratories on vaginal swab cultures were retrospectively analyzed detect maternal carriers.Each specimen was inoculated onto 5% blood agar plate incubated at...
Background The prevalence of neonatal group B streptococcal infection depends mainly on the colonization rate pregnant women by streptococci (GBS). Although Korean GBS is considered lower than in other countries, recent data maternal are sparse. Methods From August 2008 to June 2009, swab specimens from anorectus, vagina, and urethral orifice a sample 234 were placed new Granada medium (NGM-H), tube (NGM-T), commercial NGM (NGM-B), selective Todd-Hewitt broth (S-THB) for 18∼24 hours 5% CO2...
Leiomyomas that primarily arise in the vagina are uncommon tumors with approximately 300 cases having been reported world literature (1). The diagnosis of vaginal leiomyoma is seldom made preoperatively. only way to achieve a correct on histological examination. A 30-year-old nulliparous Korean woman visited our Department Urology chief complaint cyclic urinary retention her ovulation period for past 3 years. Her medical history was unremarkable. menstrual interval 30 days. Pelvic...
Changes of the characteristics were investigated during storage peach fruits following foliar application 1-methylcyclopropene (1-MCP, 120 mg∙L-1 and 240 mg∙L-1), aminoetoxyvinylglcine (AVG, 75 a combination 1-MCP (240 mg∙L-1) AVG (75 onto trees 3 weeks before harvesting. There no significant differences in fruit including total soluble solids, acid content, Hunter's value between control 1-MCP- or AVG-treated 'Madoka' peaches ambient (25°C) cold (12°C). However, we observed delayed decrease...
국내 자생 머루(Vitis spp.)의 스틸벤 화합물 함량, 총 페놀 및 플라보노이드 항산화능 측정 등의 분석을 수행하였다. 포도에 존재하는 여러 종류의 함량을 비교 분석한 결과, 머루(V. coignetiae) 계통 ‘Vc-3-09-05’, ‘Vc-1-09-22’와 새머루(V. flexsuosa) 계통인 ‘Vf-1’, ‘Vf-2’, 왕머루(V. amurensis) ‘Va-1’에서 화합물의 함량이 높게 나타났다. Trans-resveratrol 함량도 비슷한 경향이었으나 ‘Va-1’에서는 유럽 양조용인 ‘Cabernet Sauvignon’과‘Pinot Noir’와는 큰 차이를 보이지 않았고, ‘Campbell Early’와 ‘Kyoho’보다는 더 높은 보였다. 플라보노이드는 ‘Vf-GS’, ‘Va-CS’, ‘Vc-3-09-05’에서 함량으로 검출되었다. Trans-resveratrol의 높았던 ‘Vc-3-09-05’는 ABTS radical, DPPH radical 소거능...
Abstract Background The obstetrics and gynaecology (OB-GYN) residency training program in Lao People’s Democratic Republic (PDR) began 2003 based on the Millennium Development Goals (MDGs) ‘Reproductive, maternal, newborn, child health interventions (RMNCH) strategies action plan’. However, had not been properly evaluated previously. purpose of this study is to evaluate current postgraduate OB-GYN PDR by using CIPP model identify problems (the strengths weaknesses) suggest a future plan...
Abstract Increased body fluids during pregnancy complicates the application of estimated glomerular filtration rate (eGFR) formulas that are based on surface area. Furthermore, gestational renal dysfunction cannot be identified if serum creatinine (SCr) concentration is within non-pregnant reference interval (RI) despite inadequate pregnancy-related hyperfiltration. 1484 SCr measurements from 957 healthy pregnant women were collected. The average value week (GW) 0–3 was representative...
Endometriosis is a complex disease with diverse etiologies, including hormonal, immunological, and environmental factors; however, its exact pathogenesis remains unknown. While surgical approaches are the diagnostic therapeutic gold standard, identifying endometriosis-associated genes crucial first step. Endometriosis-related five gene expression studies were selected from available datasets. Approximately, 14,167 common to these datasets analyzed for differential expression. Meta-analyses...
Choi SJ, Lee S, B, Jang JY, Cho J, Uh Y. Comparison of neonatal reference intervals for 23 biochemical analytes in the cord blood-A single center study South Korea. Turk J Pediatr 2019; 61: 337-344. Reference laboratory tests are important diagnosis and treatment disease. However, due to difficulty recruiting sufficient numbers subjects, studies regarding neonates is lacking. The aim this was compare validate blood neonates. From August December 2017, 79 consecutive born at Wonju Severance...
The purpose of this study was to evaluate the effectiveness scheduled ramosetron injections for controlling postoperative nausea and vomiting (PONV) after single-port access total laparoscopic hysterectomy (SPA-TLH).Ninety patients who underwent SPA-TLH at Korean National Health Insurance Service Ilsan Hospital between June 2013 July 2014 were enrolled in prospective, randomized, double-blinded, placebo-controlled study. divided into 2 groups as follows: group (0.3 mg intravenously [IV];...