A5111532919- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Receptor Mechanisms and Signaling
- Autism Spectrum Disorder Research
- Parkinson's Disease Mechanisms and Treatments
- Neuroendocrine regulation and behavior
- Nicotinic Acetylcholine Receptors Study
- Diet and metabolism studies
- Nerve injury and regeneration
- Attention Deficit Hyperactivity Disorder
- Neuropeptides and Animal Physiology
- Botulinum Toxin and Related Neurological Disorders
- Neurogenesis and neuroplasticity mechanisms
- Alcohol Consumption and Health Effects
- Genetics and Neurodevelopmental Disorders
- Axon Guidance and Neuronal Signaling
- Memory and Neural Mechanisms
- Adipose Tissue and Metabolism
- Stress Responses and Cortisol
- Biochemical Analysis and Sensing Techniques
- Tea Polyphenols and Effects
- Exercise and Physiological Responses
- Tryptophan and brain disorders
- Child Nutrition and Feeding Issues
- Alzheimer's disease research and treatments
Rutgers, The State University of New Jersey
2013-2024
Environmental and Occupational Health Sciences Institute
2010-2017
Rutgers Sexual and Reproductive Health and Rights
2003-2008
Johnson & Johnson (Sweden)
2006
Nara Medical University
1999
University of Chicago
1979-1985
Emory University
1981
Western Michigan University
1979-1980
Individuals with autism spectrum disorder are heterogeneous in clinical presentation, concurrent disorders, and developmental outcomes. This study characterized the co-occurrences potential subgroups 160 children disorders who presented to The Autism Center between 1999 2003. Medical psychiatric included sleep epilepsy, food intolerance, gastrointestinal dysfunction, mood disorder, aggressive self-injurious behaviors. Sleep were associated dysfunction (P < .05) .01). Food intolerance was =...
Gastrointestinal (GI) dysfunctions are frequently reported by parents of children with autism spectrum disorders (ASD) and have been recently recognized as a comorbid condition. However, the clinical significance these GI remains to be delineated. This study describes characteristics, associated disorders, endoscopic colonoscopic evaluation dysfunction in cohort 164 ASD evaluated at pediatric neurology practice. Symptoms were prevalent: 49% one or more chronic complaints, 22% exhibited...
A survey on sleep schedule, health, school performance and start times was conducted in 1,941 adolescents. high level of early circadian-disadvantaged sleep/wake schedules during weekdays observed. Shorter duration reported, especially upper classmen. Complaints inadequate sleepiness weekdays, alarm clock use, napping were prevalent. Night awakening prolonged onset common associated with poor performance. Students a length less than 7 hours both weekends exhibited poorer performance, while...
The proper functions of cortical circuits are dependent upon both appropriate neuronal subtype specification and their maturation to receive signaling. These events establish a balanced circuit that is important for learning, memory, emotion, complex motor behaviors. Recent research points mRNA metabolism as key regulator this development process. Hu antigen D (HuD), an RNA-binding protein, has been implicated in the establishment identity neurite outgrowth vitro . Therefore, we investigated...
Dopaminergic neurons in the substantia nigra and ventral tegmental area project to caudate putamen nucleus accumbens/olfactory tubercle, respectively, constituting mesostriatal mesolimbic pathways. The molecular signals that confer target specificity of different dopaminergic are not known. We now report EphB1 ephrin-B2, a receptor ligand Eph family, candidate guidance molecules for development these distinct ephrin-B2 expressed complementary patterns midbrain their targets, specifically...
Epidemiological studies suggest that physical activity reduces the risk of colon cancer in humans. Results from animal studies, however, are inconclusive. The present study investigated effects voluntary exercise on intestinal tumor formation two different models, Apc(Min/+) mice and azoxymethane (AOM)/dextran sulfate sodium (DSS)-treated mice.In Experiments 1 2, five-week old female were either housed regular cages or equipped with a running wheel for 6 weeks (for maintained AIN93G diet;...
Abstract Synucleins have attracted much attention because of their involvement in several neurodegenerative disorders. In a screening for genes differentially expressed after high‐dose cocaine exposure, we found γ‐synuclein as major upregulated candidate the tegmentum. Overexpression both α‐ and drug treatment was confirmed by means microarrays, yielding an increase hippocampus, striatum tegmentum (2.65 ×, 1.96 × 3.5 respectively, α‐synuclein vs. 2.7 7.16 γ‐synuclein), but no change nucleus...