Rupert Schupfner

ORCID: 0000-0002-5427-2234
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About
Contact & Profiles
Research Areas
  • Spinal Fractures and Fixation Techniques
  • Hip and Femur Fractures
  • Pelvic and Acetabular Injuries
  • Spine and Intervertebral Disc Pathology
  • Trauma and Emergency Care Studies
  • Pleural and Pulmonary Diseases
  • Salivary Gland Tumors Diagnosis and Treatment
  • Cardiac Valve Diseases and Treatments
  • Medical Imaging and Analysis
  • Scoliosis diagnosis and treatment
  • Sports Performance and Training
  • Cardiovascular and exercise physiology
  • Orthopaedic implants and arthroplasty
  • Thyroid Cancer Diagnosis and Treatment
  • Trauma Management and Diagnosis
  • Proteoglycans and glycosaminoglycans research
  • Shoulder Injury and Treatment
  • Clinical practice guidelines implementation
  • Shoulder and Clavicle Injuries
  • Myasthenia Gravis and Thymoma
  • Child and Adolescent Health
  • Osteoarthritis Treatment and Mechanisms
  • Cardiovascular Effects of Exercise
  • TGF-β signaling in diseases
  • Health and Medical Studies

Bayreuth Medical Center
2013-2020

Ludwig-Maximilians-Universität München
2002

Background: Bone-graft substitutes are commonly used for the augmentation of traumatic bone defects in tibial plateau fractures. However, their clinical performance compared with that autologous bone-grafting, gold standard defect reconstruction, still remains under debate. This study investigates differences quality life, pain, and radiographic outcomes treatment fracture-associated either grafts or a bioresorbable hydroxyapatite calcium sulfate cement (CERAMENT BONE VOID FILLER [CBVF];...

10.2106/jbjs.19.00680 article EN cc-by-nc-nd Journal of Bone and Joint Surgery 2019-12-06

Background: The heterogeneity of patients with osteoporotic vertebral compression fractures (VCF) necessitates a tailored approach balancing the benefits and limitations available treatments. Current guidelines are divergent, sometimes contradictory, often insufficiently detailed to guide practice decisions. Objectives: This study aimed at establishing treatment recommendations patientspecific level. Study Design: Using RAND/UCLA Appropriateness Method (RAM), appropriateness different...

10.36076/ppj.2013/16/e519 article EN Pain Physician 2013-09-14

Mesenchymal stem cells (MSCs) become hypertrophic in long term despite chondrogenic differentiation following the pathway of growth plate chondrocytes. This terminal leads to phenotypically unstable cartilage and was mirrored vitro by addition hypertrophy inducing medium. We investigated how intrinsic TGF-β signaling is altered pro-hypertrophic conditions.Human bone marrow derived MSC were chondrogenically differentiated 3D culture. At day 14 medium conditions changed 1. T3 withdrawal...

10.15283/ijsc18088 article EN International Journal of Stem Cells 2019-02-27

CASTLE (Carcinoma showing thymus-like elements) is a rare malignant neoplasm of the thyroid resembling lymphoepithelioma-like and squamous cell carcinoma thymus with different biological behaviour better prognosis than anaplastic thyroid.We retrospectively investigated 6 cases this very in order to investigate mutational status KRAS, EGFR, PDGFR-α KIT, as well immunohistochemical expression pattern CD117, EGFR COX-2, possibly find new therapeutic targets.Diagnosis was confirmed by moderate...

10.1186/1746-1596-9-116 article EN cc-by Diagnostic Pathology 2014-06-16

IntroductionPercutaneous vertebral augmentation is a common therapeutic approach for osteoporotic or osteolytic fractures. Due to the variable pedicle anatomy two different approaches, transpedicular and extrapedicular have been established. In particular, in middle upper thoracic spine, percutaneous procedures are challenging because of difficult visualisation anatomical landmarks more unfavourable with smaller differently orientated pedicles.Material methodsIn our cadaveric study we...

10.1016/j.injury.2020.11.017 article EN cc-by-nc-nd Injury 2020-11-06

horax injuries are to be found in approximately 78% amongst all accident victims. Moreover, they implicate an increase mortality rate. Consequently, adequate contemporary treatment has begin preclinically, even if the conditions less comfortable than a clinical setting. Emergency doctors need familiar with placement of chest tubes.

10.1556/imas.5.2013.4.4 article EN cc-by-nc Interventional Medicine and Applied Science 2013-12-01

Background The sports medicine performance diagnostics include investigative procedures that supply information on the capacity and stamina of an athlete. This creates a foundation for personalised training plan enables optimised control process.Methodology study population consisted 24 male Nordic combined athletes from national German squad. They were monitored using over period five winter seasons. test speeds treadmill in m/s are determined at lactate values 2, 3 4 mmol/l peripheral...

10.1080/00913847.2020.1796181 article EN The Physician and Sportsmedicine 2020-07-14

Objective To describe and analyze a new method of treating fragility fractures the pelvis in elderly patients, cement augmentable Transiliac Internal Fixator (TIFI). Methods We reviewed 196 patients older than 59 years with pelvic ring fracture who had been treated period from January 2004 through November 2014. They were 11 men 93 women, aged to 94 (average, 77.5±7.6 years). By Romens classification, there 31 cases type Ⅰ, 39 ones Ⅱ, 19 Ⅲ 15 Ⅳ. The causes for included fall standing...

10.3760/cma.j.issn.1671-7600.2017.05.012 article EN 2017-05-15

Introduction: Thoracolumbar osteoporotic vertebral fractures often occur in elderly patients.Possible treatment options include conservative therapy with orthoses and minimally invasive therapies like balloon kyphoplasty.Studies show advantages pain reduction post-kyphoplasty.In contrast, activating seem to have a longer-term positive effect on muscles thus the sagittal plane of spine.Aim: This prospective comparative study was designed investigate differences regarding relief, mobility,...

10.19080/oroaj.2020.16.555932 article EN Orthopedics and Rheumatology Open Access Journal 2020-05-11
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