- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Family and Disability Support Research
- Stroke Rehabilitation and Recovery
- Infant Development and Preterm Care
- Neurogenetic and Muscular Disorders Research
- Muscle activation and electromyography studies
- Assistive Technology in Communication and Mobility
- Neonatal and fetal brain pathology
- Foot and Ankle Surgery
- Nerve Injury and Rehabilitation
- Children's Physical and Motor Development
- Down syndrome and intellectual disability research
- Hand Gesture Recognition Systems
- Motor Control and Adaptation
- Child Nutrition and Feeding Issues
- Diabetic Foot Ulcer Assessment and Management
- Sports Performance and Training
- Balance, Gait, and Falls Prevention
- Lower Extremity Biomechanics and Pathologies
- Advanced Neuroimaging Techniques and Applications
Karolinska Institutet
2014-2024
Karolinska University Hospital
2017-2024
KTH Royal Institute of Technology
2015
To support clinical decision-making in central neurological disorders, a physical examination is used to assess responses passive muscle stretch. However, what exactly being assessed expressed and interpreted different ways. A clear diagnostic framework lacking. Therefore, the aim was arrive at unambiguous terminology about concepts measurement around pathophysiological neuromuscular response stretch.During two consensus meetings, 37 experts from 12 European countries filled online...
Abstract Background Individuals with cerebral palsy (CP) are less physically active, spend more time sedentary and have lower cardiorespiratory endurance as compared to typically developed individuals. RaceRunning enables high-intensity exercise in individuals CP limited or no walking ability, using a three-wheeled running bike saddle chest plate for support, but pedals. Training adaptations this type of unknown. Methods Fifteen adolescents/young adults (mean age 16, range 9–29, 7 females/8...
In children with bilateral cerebral palsy (CP) maintaining a standing position can be difficult. The fundamental motor task of independently is achieved by an interaction between the visual, somatosensory, and vestibular systems. CP, disorders are commonly accompanied sensory perceptual disturbances. Our aims were to examine influence visual stimuli on posture in relation ability.Three dimensional motion analysis surface electromyography was recorded describe body position, movement, muscle...
To explore whether focusing a target influenced gait in children with cerebral palsy (CP) and typical development (TD).Thirty bilateral CP (Gross Motor Function Classification System [GMFCS] I-III) 22 TD looked at light walkway end (Gaze Target) while walking returned (No Target).During Gaze versus No Target, reduced temporal-spatial parameters movements the sagittal (SPM) transverse planes. In comparison, during CP1 (GMFCS I) had larger trunk SPM, CP2 II) neck (SPM), CP3 III) greater head...
The motor disorders of cerebral palsy (CP) are often accompanied by sensory disturbances, but knowledge their relationship to functioning is sparse. This study explored responses events in relation spastic subtype and children with CP. Parents 60 CP (unilateral: 18, bilateral: 42) GMFCS levels I:29, II:13, III:15 IV:3 mean age 12.3 years (3.7 SD) participated. parents (n = 55) rated children´s the norm-referenced questionnaire Child Sensory Profile-2© (CSP-2©), Swedish version, incorporating...
Thirty children with cerebral palsy (CP) and 22 typical developing (TD) were tested 3D-gait analysis. At turning, trunk rotation was larger in CP2 (GMFCS II) than TD CP1 I), head flexion CP3 III) TD. Maximum values during the entire trial other groups, Trial time increased GMFCS-level. Less reflects spatial insecurity CP2, which is compensated by walker. The flexed may reflect deficits proprioception sensation requiring visual control of lower limbs.
In children with motor disabilities, knee position during walking is often of concern in rehabilitation. This study aimed to investigate joint sense. Thirty-seven Cerebral Palsy (CP), 21 Myelomeningocele (MMC), 19 Arthrogryposis (AMC), and 42 TD participated the study. Knee sense, i.e., difference between criterion angle reproduced (JPS-error), was assessed sitting while 3D motion capture recorded at flexed 70 (Knee70), 45 (Knee45), 20 (Knee20) degrees, after three seconds maintained (CAM)...
In Brief Purpose: To investigate postural orientation and maintenance of joint position during standing in children with bilateral spastic cerebral palsy (BSCP). Methods: Standing was examined 3-D motion analysis 26 BSCP, 19 typically developing (TD). Two groups (CP) were analyzed: 15 who able to maintain without support 11 needed support. Results: Children CP stood more flexion than TD. the groups, asymmetrically less hip knee movement those required Conclusion: had varying abilities stand...
In bilateral cerebral palsy (CP) muscle strength is considered important for development of gross motor functions, but its influence on standing ability has not been explored. Our aims were to examine with respect the stand (SwS) or without (SwoS) hand support, asymmetrical weight bearing (WB), and whether produce was influenced by different seated conditions. this cross sectional descriptive study posture recorded 3D motion analysis, measured a hand-held dynamometer, in 25 children CP,...
Abstract Aim To create a shortened, more user‐friendly Second Edition of the Dyskinesia Impairment Scale (DIS‐II) to assess dystonia and choreoathetosis, evaluate its construct validity reliability. Method development included an online expert meeting ( n = 21) iterative discussions within research group 6). A Rasch measurement model analysis on DIS scores from individuals with dyskinetic cerebral palsy or inherited/idiopathic 123, 74 males, mean age 14 years, SD 5 years) was performed...
BACKGROUND: Among children with cerebral palsy (CP) some choose to be mobile by crawling or walking on their knees despite bipedal ability. This motor behavior raises questions; so, we wanted enhance understanding of the child’s choice mobility.AIM: To explore gross abilities in positions various postural demands focusing floor mobility among CP.DESIGN: A cross-sectional observational study.SETTING: The study was performed at Neuropediatric Outpatient Department Karolinska University...
The Dyskinesia Impairment Scale (DIS) is a new assessment scale for dystonia and choreoathetosis in children youth with dyskinetic cerebral palsy. Today, the Burke-Fahn-Marsden Dystonia Rating (BFM) mostly used to assess inherited dystonia. aim of this study was reliability validity DIS or idiopathic dystonia.Reliability measured by (1) intraclass correlation coefficients (ICCs) inter-rater test-retest reliability, as well (2) standard error measurement (SEM) minimal detectable difference...
Spasticity and dyskinesia are motor signs that co-exist in cerebral palsy (CP). It is well accepted that, spastic bilateral CP, dystonia can be present addition to spasticity, equally spasticity often individuals with dyskinetic CP. In unilateral of the upper extremity only rarely identified or addressed. The aim this study was investigate if hand children and, present, what extent, when it first noticeable.Ninety-seven born 1999-2014, standardized digital films function from Assisting Hand...
Abstract Background Musculoskeletal alterations causing reduced range of motion the ankle joint are common in children with cerebral palsy (CP). Objective measurements passive resistance and three-dimensional skeletal muscle volume architecture can lead to a comprehensive understanding which factors influence motion. Research question To investigate relation between dorsiflexion joint, biomechanical contributing resistance, muscular architectural properties triceps surae CP. Methods In this...
Abstract Aim The aim of this Swedish study was to evaluate the assessment clinical signs perceptual disorder in children with cerebral palsy (CP). Methods Three experienced raters assessed 56 videos 19 from 1 18 years age bilateral spastic CP, which were recorded by colleagues at an Italian hospital. Six evaluated for inter‐rater reliability and criterion validity. Clinical applicability assessing between 47 clinicians, who examined 15 during face‐to‐face online education seminars. There 41...
The aim was to explore longitudinal motor development in children with cerebral palsy (CP) Sweden respect the Gross Motor Function Classification System (GMFCS). In this national CP registry-based study, 2138 aged 0.5-19 years participated (42% girls). distribution GMFCS I: 49%, II: 16%, III: 10%, IV: 14%, and V: 11%. total, 5538 assessments (mean 2.7, min-max: 1-9) Measure-66 were included. Data analysed using non-linear mixed-effects regression models, Stable Limit Model selected fit data....
Objective. The purpose of this cross-sectional study was to investigate muscle strength and possible influence on gait in high-functioning young individuals with unilateral cerebral palsy. Methods. Forty-four a mean age 17.5 years (range 13.0–24.0 years) 23 matched controls participated. Maximal voluntary isometric contraction measured chair. moments (torque) work were calculated from three-dimensional analysis. Results. maximal knee extensors the involved side 1.56 Nm/kg, compared 2.4 Nm/kg...
and show similar developmental benefits of independent mobility as their able bodied peers (Butler 1983).Yet, provision powered wheelchairs has often been limited by the availability suitable equipment funding.The 'Wizzybug' is a toddler's 'first wheels'.Wizzybug was designed charity Designability in response to recognition value early years mobility.It collaborative project involving families steered therapists.Following an evaluation programme 2007 BIME launched Wizzybug product,...