- Remote Sensing and LiDAR Applications
- Forest ecology and management
- COVID-19 Clinical Research Studies
- Dental Health and Care Utilization
- Cardiovascular Function and Risk Factors
- Long-Term Effects of COVID-19
- Lipoproteins and Cardiovascular Health
- Point processes and geometric inequalities
- Forest Management and Policy
- Cardiac Health and Mental Health
- Salivary Gland Disorders and Functions
- Oral microbiology and periodontitis research
- Melanoma and MAPK Pathways
- Acute Myocardial Infarction Research
- Pharmaceutical Practices and Patient Outcomes
- Adsorption, diffusion, and thermodynamic properties of materials
- Oral and gingival health research
- Sleep and Work-Related Fatigue
- Autoimmune Bullous Skin Diseases
- Pickering emulsions and particle stabilization
- Cardiovascular Health and Disease Prevention
- Morphological variations and asymmetry
- Uterine Myomas and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Parvovirus B19 Infection Studies
Karolinska Institutet
2019-2024
Chalmers University of Technology
2013-2019
Natural Resources Institute Finland
2019
University of Gothenburg
2013-2017
University Medical Center Freiburg
1986-1988
Obstructive sleep apnea (OSA) is associated with an increased risk of motor vehicle accidents (MVAs). The rate MVAs in patients suspected having OSA was determined and the effect continuous positive airway pressure (CPAP) investigated. MVA referred for compared to general population using data from Swedish Traffic Accident Registry (STRADA), stratified age calendar year. factors MVAs, demographic polygraphy data, before after CPAP were evaluated patient group. Clinical laboratory based...
Abstract Background Disturbances in brain cholesterol homeostasis may be involved the pathogenesis of Alzheimer’s disease (AD). Lipid-lowering medications could interfere with neurodegenerative processes AD through metabolism or other mechanisms. Objective To explore association between use lipid-lowering and cognitive decline over time a cohort patients mixed dementia indication for treatment. Methods A longitudinal study using Swedish Registry Cognitive/Dementia Disorders, linked national...
Importance Nonsuicidal self-injury is prevalent in adolescence and associated with adverse clinical outcomes. Effective interventions that are brief, transportable, scalable lacking. Objective To test the hypotheses an internet-delivered emotion regulation individual therapy for adolescents delivered adjunctive to treatment as usual superior only reducing nonsuicidal improvements mediate these effects. Design, Setting, Participants This 3-site, single-masked, randomized superiority trial...
Aims The risks associated with diabetes, obesity and hypertension for severe COVID-19 may be confounded differ by sociodemographic background. We assessed the cardiometabolic factors when accounting socioeconomic in subgroups age, sex region of birth. Methods results In this nationwide case–control study, 1.086 patients admitted to intensive care requiring mechanical ventilation (cases), 10.860 population-based controls matched district residency were included from mandatory national...
Low socioeconomic status (SES) is associated with poor long-term prognosis after myocardial infarction (MI). Plausible underlying mechanisms have received limited study.To assess whether SES risk factor target achievements or risk-modifying activities, including cardiac rehabilitation programs, monitoring, and drug therapies, during the first year MI.This cohort study included a population-based consecutive sample of 30 191 one-year survivors first-ever MI who were 18 to 76 years age,...
Abstract Background Whether early fluid accumulation is a risk factor for adverse renal outcomes in septic intensive care unit (ICU) patients remains uncertain. We assessed the association between cumulative balance and major kidney events within 30 days (MAKE30), composite of death, dialysis, or sustained dysfunction, such patients. Methods performed multicenter, retrospective observational study 1834 admitted to five ICUs three hospitals Stockholm, Sweden. used logistic regression analysis...
Abstract Background Periodontal disease has been proposed as a putative etiological factor for dementia. The aim of this investigation was to compare the incidence dementia in individuals with or without deep probing pocket depths (DPPD), serving proxy periodontitis. Methods In cohort study, conducted Sweden, we identified 7992 DPPD and 29,182 matched (non‐DPPD), using Swedish Quality Registry Caries Diseases (SKaPa). two groups were followed incident (mean follow‐up time 7.6 years) based on...
In the emergency department (ED), high blood pressure (BP) is commonly observed but mostly used to evaluate patients' health in short term. We aimed study whether ED-measured BP associated with incident atherosclerotic cardiovascular disease (ASCVD), myocardial infarction, or stroke long term, and estimate number needed screen prevent ASCVD. this cohort study, participants were selected from a university hospital between 2010 2016, an obtained ED. The outcome information was acquired through...
To assess if women with obesity have increased complication rates compared normal weight undergoing hysterectomy for benign reasons and the mode of affects outcomes.Cohort study.Prospectively collected data from 3 Swedish population-based registers.Women a total indications in Sweden between January 1, 2015, December 31, 2017. The patients were grouped according to World Health Organization's classification obesity.Intraoperative postoperative retrieved surgical register up 1 year after...
Abstract Aims To investigate plasma lipoprotein(a) [Lp(a)] levels measured in routine clinical care and their association with mortality cardiovascular disease. Methods results This retrospective registry-based observational cohort study includes all individuals Lp(a) at the Karolinska University Laboratory 2003–17. Outcome data were captured national outcome registries. Levels of expressed mass or molar units examined separately. In adjusted Cox regression models, between deciles...
Chronic kidney disease (CKD) is a risk factor for acquiring severe COVID-19, but underlying mechanisms are unknown. We aimed to study the associated with CKD COVID-19 outcomes in relation body mass index (BMI) and diabetes because they common factors both COVID-19.This nationwide case-control data from mandatory national registries included 4684 patients (cases) admitted intensive care units (ICUs) requiring mechanical ventilation 46,840 population-based controls matched by age, sex,...
Low socioeconomic status is associated with worse secondary prevention use and prognosis after myocardial infarction (MI). Actions for health equity improvements warrant identification of risk mediators. Therefore, we assessed mediators the association between first recurrent atherosclerotic cardiovascular disease event (rASCVD) MI.In this cohort study on 1-year survivors first-ever MI Swedish universal coverage ages 18 to 76 years, individual-level data from SWEDEHEART (Swedish Web System...
In northern rural Sweden, telemedicine is used to improve access healthcare and provide patient-centered care. emergency care during on-call hours, video-conference systems are connect the physicians rest of team - creating 'distributed teams'. Patient participation a core competency for professionals. Knowledge about how distributed teamwork affects patient missing. The aim was investigate if affecting participation, as well clinicians' perceptions regarding shared decision-making differ...
Background Anakinra and tocilizumab are used for severe Covid-19, but only one previous randomized controlled trial (RCT) has studied both. We performed a multi-center RCT comparing anakinra or versus usual care (UC) adults at high risk of deterioration. Methods The study was conducted June 2020 to March 2021. Eligibility required ≥ 5 liters/minute Oxygen maintain peripheral oxygen saturation 93%, CRP > 70 mg/L, ferritin 500 μg/L least two points where point awarded lymphocytes < 1x 10...
Psoriasis is an immune-mediated chronic inflammatory disease having a significant negative health impact. has societal impact; loss of productivity been estimated at approximately 10% and it may influence the patient's financial status. Relationships between quality life, severity, cost care need exploration. Understanding burden important for policy research allocation. Few studies address gaps in socioeconomics, comorbidity, medication use.Observing differences education, income,...
Objectives Psychosocial work demands and physical workload are important causes of ill health. The dramatic demographic changes in society make it to understand if such factors change with ageing, but this is presently not known. purpose the present study was investigate whether psychosocial across 8 years occupational groups show different trajectories reflected sleep or fatigue. Methods A cohort 5377 participants (mean age: 47.6±11.6 (SD) years, 43.2% males, 40.2% blue-collar workers)...
We investigated how the precision and costs of forest resource estimates for sample plots different type size depend on spatial structure forests jointly studied effects tree density distribution. Statistically thinking, trees in a can be regarded as point pattern. Based properties pattern, we classified into clustered, random, regular. used empirical data from 396 mapped Finland. The variance unbiased Horvitz-Thompson estimator expected basal area estimation were calculated 99 each plots....
Abstract Introduction The increase in the migration of dentists educated outside EU / EEA calls for sharing information and evaluation recognition processes within countries . In 2017, Swedish National Board Health Welfare implemented Proficiency test , a process who have completed an education programme consists theoretical integrated clinical skills examination, followed by 6‐month practice. examination is two‐part that includes OSCE operative on dental manikin. This paper presents data...
Abstract Background The glycemic response to critical COVID‐19 remains uncertain. We aimed assess the association between COVID‐19, insulin requirements, control, and mortality in intensive care unit (ICU) patients. Methods conducted a retrospective observational study of 350 patients 1067 non‐COVID‐19 admitted ICU. Insulin requirement was defined as total units exogenous required cover one gram administered carbohydrates (insulin‐to‐carbohydrate ratio, ICR). used multivariable generalized...