A5102735411- Cardiac Valve Diseases and Treatments
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Additive Manufacturing and 3D Printing Technologies
- Protease and Inhibitor Mechanisms
- Cardiac Imaging and Diagnostics
- Cell Adhesion Molecules Research
- Cardiac and Coronary Surgery Techniques
- Tissue Engineering and Regenerative Medicine
- Aortic aneurysm repair treatments
- Elasticity and Material Modeling
- Infectious Aortic and Vascular Conditions
- Cardiovascular Function and Risk Factors
- Blood properties and coagulation
- Collagen: Extraction and Characterization
- Aortic Disease and Treatment Approaches
Cornell University
2019-2023
The Ohio State University
2016-2020
Abstract The quantity and quality of collagen fibrils in the extracellular matrix (ECM) have a pivotal role dictating biological processes. Several collagen-binding proteins (CBPs) are known to modulate deposition fibril diameter. However, limited studies exist on alterations ultrastructure by CBPs. In this study, we elucidate how receptor, discoidin domain receptor 1 (DDR1) regulates content adventitia DDR1 knock-out (KO) mice. KO mice exhibit increased as observed using Masson’s trichrome....
Background Mitral regurgitation ( MR ) has the potential to impede exercise capacity; it is uncertain whether this because of itself or underlying cause valvular insufficiency. Methods and Results The population comprised 3267 patients who underwent treadmill myocardial perfusion imaging transthoracic echocardiography within 6±8 days. was present in 28%, including 176 (5%) with moderate greater . Left ventricular systolic function significantly decreased chamber size increased relation ,...
Objective: Bioprinting has strengthened the ability to create complex materials replace dysfunctional tissue and been used replicate geometry of heart valves. Additionally, embedded printing expanded range bioprintable materials. However, bioprinting microstructure leaflets remains difficult with traditional methods. Extrusion printers can be programmed move in non-planar directions bioprint tissues (BENT) by following surfaces reproduce structures such as valve leaflets.Methods: Valve...