A5070676757- Systemic Sclerosis and Related Diseases
- Dermatologic Treatments and Research
- Skin Diseases and Diabetes
- Skin Protection and Aging
- Textile materials and evaluations
- Nail Diseases and Treatments
- Dermatology and Skin Diseases
- Autoimmune Bullous Skin Diseases
- Acne and Rosacea Treatments and Effects
- Advancements in Transdermal Drug Delivery
- Herpesvirus Infections and Treatments
- Nonmelanoma Skin Cancer Studies
- Psoriasis: Treatment and Pathogenesis
- Oral and gingival health research
- Meta-analysis and systematic reviews
- Dermatological diseases and infestations
- Ethics in Clinical Research
- Plant Pathogens and Fungal Diseases
- Dermatological and COVID-19 studies
- Cytomegalovirus and herpesvirus research
- Biomedical Ethics and Regulation
- Genetic and rare skin diseases.
- Infrared Thermography in Medicine
- Effects and risks of endocrine disrupting chemicals
- Thermoregulation and physiological responses
Medical University Plovdiv
2015-2024
Lozenetz Hospital
2023
Translational Research Institute
2016
The University of Queensland
2016
Universität Innsbruck
2015
Sofia University "St. Kliment Ohridski"
2015
University Dermatology
2015
Military Medical Academy
2014
Background/aims: The Cutometer equipped with a 2‐mm diameter suction probe is device suitable for assessment of epidermal mechanics. objectives this study were to determine the sensitivity parameters hydration, evaluate correlation between skin mechanical and capacitance, role pretension skin. Methods: In first study, capacitance (Corneometer) 10 determined before 60 min after application five different moisturizers on volar forearm. second measurements mechanics made without 0.1 s...
Background/aim: The age‐related decrease of skin elasticity results in larger fatigue adult than young after applying multiple stress at one and the same anatomic region. aim this study was to compare informativeness Cutometer standard R ‐parameters with new area parameters regarding changes human fatigue. Materials/methods: A total 40 healthy volunteers aged 12–82 years were studied. Mechanical determined using a non‐invasive suction meter (Cutometer). Measurements made on temporal region...
Some botanical compounds are considered useful to reduce sebum production. Aim To evaluate the efficacy of a control cream containing polyphenol-rich extract from saw palmetto, sesame seeds, and argan oil in subjects with oily facial skin.The study was carried out during winter months (January February). A total 20 healthy volunteers (9 male 11 female, aged 17-50 years, 16 skin 4 combined skin) were studied. The test product applied twice daily face for period weeks. clinical assessment...
When used correctly, dermoscopy is an essential tool for helping clinicians in the diagnosis of skin diseases and early detection cancers. Despite its proven benefits, there a lack data about how European dermatologists use everyday practice.To identify motivations, obstacles modifiable factors influencing daily dermatology practice across Europe.All registered 32 countries were invited to complete online survey 20 questions regarding demographic characteristics, training self-confidence...
Raynaud's phenomenon (RP) is usually the first symptom in patients with systemic sclerosis (SS) and may precede skin changes by several months or years. Non-invasive measurements of elasticity are very sensitive appropriate for objective quantitative evaluation sclerodermatous skin. The aim this study was to investigate compare mechanical properties primary, secondary, suspected secondary RP.A total 63 were studied. They classified as having scleroderma-type nailfold capillary...
The aim of this study was to investigate the mechanical properties skin in psoriatic plaques before and after treatment with dithranol clinically uninvolved comparison healthy controls. In total, 82 19 in-patients 51 age-matched control subjects were studied a non-invasive suction device (Cutometer). characterized by statistically significant lower distensibility elasticity, higher viscoelastic elastic ratio compared adjacent apparently normal skin. Delayed distension hysteresis measured...
Journal Article Postherpetic abdominal‐wall pseudohernia Get access H. Dobrev, Dobrev Departments of Dermatology Dr Hristo MD, PhD, Department Dermatology, Medical University, 15A Vasil Aprilov Str. 4002 Plovdiv, Bulgaria. E‐mail: hristo_dobrev@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar P. Atanassova, Atanassova Neurology V. Sirakov Imaging Diagnostics, Bulgaria Clinical and Experimental Volume 33, Issue 5, 1 September 2008, Pages 677–678,...
Orange-red fluorescence in the follicle openings, induced by ultraviolet A light, originates from porphyrins, metabolic products of Propionibacteria acnes.To investigate relationship orange-red follicular with severity acne and amount sebum secretion.Twenty-five volunteers were included. The was rated on a 4-point scale. casual level measured using Sebumeter determined camera Visiopor.Casual intensity (percentage area number spots) higher at T zone than U all patients regardless their skin...
Twenty patients with scalp seborrhoeic dermatitis were treated twice weekly ketoconazole 2% shampoo for 4 weeks. Clinical assessment, culture P. ovale on Dixon broth and lipid measurement at two places made before treatment after 2 Significant improvement of the severity (p < 0.001) negative mycological tests by 19 (95%) observed. The content remained unaltered in 11 an initial value over 220 micrograms/cm2 but increased those lower values. This is probably due to sebum delivery onto skin...
Hospitalized and severely ill coronavirus disease 2019 (COVID-19) patients necessitate prophylactic or therapeutic anticoagulation to minimize the risk of thrombosis at different sites. Life-threatening bleeding complications include spontaneous iliopsoas hematoma, peritoneal bleeding, extra-abdominal manifestations such as intracranial hemorrhage.Bleeding in abdominal wall results less severe than seen with hematoma bleeding. In our case series 9 patients, we present retroperitoneal...
Mechanical behavior of the skin can be evaluated by different non-invasive methods. In this study, we applied a new measurement device based on indentometry to determine mechanical properties in healthy individuals and patients with systemic sclerosis (SSc).
Background/aims: Inflammatory dermal oedema in erysipelas alters skin mechanics. The aims of this study were to determine the relationship between mechanical properties and changes water content patients with lower leg, assess value measuring elasticity monitoring effect therapy. Methods: Twenty‐five in‐patients studied before treatment after 10 20 days. Visual scoring oedema, measurements limb circumference a non‐invasive suction device (Cutometer) made on affected unaffected legs. Results:...
A non-invasive, in vivo suction device was used to investigate the mechanical properties of skin a patient with scleredema Buschke. Clinical scoring induration and measurements elasticity were performed over 9 anatomic regions on admission after 3 (on discharge), 17 28 months. Immediate distension, final distension immediate retraction significantly decreased, while viscoelastic elastic ratio increased as compared healthy controls. Delayed biological preserved. Low values distensibility...
We report a case of scleredema Buschke associated with IgG kappa monoclonal hypergammaglobulinaemia. After myeloma polychemotherapy an improvement in skin involvement was observed and confirmed by means noninvasive elasticity measurements. This suggests relationship between the two diseases. The bioengineering method used can be useful for early detection monitoring patients this disease association.
Diagnosis of systemic sclerosis (SSc) at very early stage could allow starting an appropriate therapy and improving the patient outcome. Skin involvement is often first non-Raynaud's phenomenon (RP) symptom. Its uncovering may play important role for initial diagnosis.To introduce a simplified method non-invasive evaluation skin mechanical properties in patients with clinically evident or suspected SSc.A total 94 162 healthy subjects were studied. According to clinical nailfold...
Kindler syndrome (KS), the fourth major type of hereditary epidermolysis bullosa (HEB), is a rare, autosomal recessive disorder characterized by skin fragility and blistering at birth followed development marked photosensitivity progressive poikilodermatous changes in later years. We reported here case 54-year-old woman, who fulfills diagnostic criteria KS HEB, putting accent on nailfold capillaroscopic changes. Using videocapillaroscopy we observed pronounced alterations finger nail...
Abstract We present a 60-year-old male patient who, three months after holiday in Southern Greece, found small ‘pimple’ on his back, which gradually got as big walnut, the central part becoming ulcerated and scabby. Dermatological examination an erythematous-to-livid nodular lesion right shoulder; it was 16 mm diameter with ulceration, covered brownish crust discharged pus-like secretion upon pressure. Microscope of Romanowsky-Giemsa stained material detected amastigote forms Leishmania...
Background/Aim: Topical indomethacin has been reported to inhibit ultraviolet light‐induced erythema. The objective of this study was verify assertion and compare 10% ointment betamethasone valerate 0.1% ointment, water‐in‐oil emulsion oil‐in‐water by means non‐invasive skin elasticity measurements. Methods: Products were applied on the back 60 min 5 before after UVL irradiation. Untreated test sites served as controls. Clinical evaluation, measurements epidermal hydration (Corneometer)...
In this study the complex interrelationship between physical factors, job stress, lifestyle and genetic factors on symptoms of work-related musculoskeletal disorders upper limbs is demonstrated by a case report discussion literature. A 58 year old woman with long lasting complaints increasing intensity duration, generalisation, combined skin thickness, Raynaud’s phenomenon, joint disorders, arterial pulmonary hypertension, metabolic lipid dysfunctions presented. Occupational history proves...