A5101648002- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Respiratory Support and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Metastasis and carcinoma case studies
- Lung Cancer Treatments and Mutations
- Global Cancer Incidence and Screening
- Nosocomial Infections in ICU
- Advanced X-ray and CT Imaging
- Long-Term Effects of COVID-19
- Statistical Methods and Inference
- Breast Lesions and Carcinomas
- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Statistical Methods and Bayesian Inference
- Radiation Dose and Imaging
- Vascular Tumors and Angiosarcomas
- Lipid metabolism and disorders
- Cancer Treatment and Pharmacology
- Surgical site infection prevention
- Kruppel-like factors research
- Mental Health Treatment and Access
- Inflammation biomarkers and pathways
Army Medical University
2024
Peking Union Medical College Hospital
2015-2022
Fudan University Shanghai Cancer Center
2010-2022
Anhui University of Finance and Economics
2021-2022
Hebei Medical University
2016-2022
Fourth Hospital of Hebei Medical University
2016-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2022
Shanghai Medical College of Fudan University
2022
Soochow University
2022
First Affiliated Hospital of Soochow University
2022
Colorectal surgery is associated with high rates of surgical site infection (SSI). We investigated SSI in radical resection colon or rectal carcinoma and its epidemiological distribution 26 hospitals China.We conducted prospective surveillance patients who underwent selected from January 2015 to June 2016.An information system monitored all the inpatients. Infection control professionals observed inpatients suspected had been screened by at bedside. The status incisions was followed up...
Objective The aim of the present study was to evaluate incidences margin involvement, disease relapse, and complications in patients who had undergone conization using an electrosurgical knife (EKC) for cervical intraepithelial neoplasia (CIN) or microinvasive carcinomas (micro-CAs). Materials Methods A retrospective case series analysis performed with a total 1359 underwent EKC Fudan University Shanghai Cancer Center between June 2004 July 2010. Results median age 39 years old (range:...
Background The purpose of this study was to investigate whether ultra-low-dose chest computed tomography (CT) can be used for visual assessment CT features in patients with pulmonary alveolar proteinosis (PAP) and evaluate the relationship between quantitative analysis scans function tests (PFTs). Methods Thirty-eight (mean [SD] age, 44.47 [12.28] years; 29 males, 9 females) PAP were enrolled subjected two each low-dose (reference parameters: 120 kV 50 mAs) parameters, 80 kV, 25 mAs). Images...
The aim of the present study was to identify potential target biomarkers associated with burn sepsis using microarray. GSE1781 downloaded from Gene Expression Omnibus and included a collective three biological replicates for each conditions: Sham‑Sham, Sham‑cecal ligation puncture (CLP) Burn‑CLP. Subsequently, limma applied screen differentially expressed genes (DEGs). Additionally, functional annotations were predicted by pathway enrichment. Furthermore, transcription factors screened...
We aimed to investigate the regulatory mechanism of lentivirus-mediated overexpression cystic fibrosis transmembrane conductance regulator (CFTR) in oxidative stress injury and inflammatory response lung tissue mouse model chronic obstructive pulmonary disease (COPD). COPD induced by cigarette smoke was established normal mice were used as control. The assigned into a group (control), (untreated), an oe-CFTR (injection lentivirus overexpressing CFTR), oe-NC (negative control, injection...
The effects of gentiopicroside (Gent), an active component derived from the traditional Chinese medicine Gentiana macrophylla, on lipopolysaccharide-induced astrocyte activation and subsequent neuronal damage were investigated. Gent significantly inhibited release tumor necrosis factor-α, interleukin-1β, nitric oxide, prostaglandin E, as well expressions inducible oxide synthase cyclooxygenase-2 in primary astrocytes. Furthermore, relieved neurotoxicity astrocyte-mediated inflammatory...
Abstract Background Gastrointestinal symptoms are not rare among coronavirus disease 2019 (COVID-19) patients, but there have been no reports regarding convalescent plasma therapy for the recovery of gastrointestinal problems in COVID-19 patients. Case presentation We present two cases patients with COVID-19-associated recurrent diarrhea and positive fecal occult blood who successfully recovered after a one-time administration. Conclusion When develop or refractory fail to respond available...
Abstract Background The timeliness of diagnostic testing after positive screening remains suboptimal because limited evidence and methodology, leading to delayed diagnosis lung cancer over-examination. We propose a radiomics approach assist with planning the interval in screening. Methods From an institute-based cohort, we retrospectively selected 92 patients pulmonary nodules diameters ≥ 3 mm at baseline (61 confirmed as by histopathology; 31 cancer-free). Four groups...
Based on the gene expression profile of patients with ventilator-associated pneumonia (VAP) and not affected by disease, present study aimed to enhance current understanding VAP development using bioinformatics methods. The GSE30385 was downloaded from Gene Expression Omnibus database. Linear Models for Microarray Data package in R language used screen identify differentially expressed genes (DEGs), which were grouped as up‑ down‑regulated genes. downregulated functionally enriched Database...
The previous study has indicated that lung cancer a high incidence and mortality in China, caused large economic burden. purpose of this was to analyze the burden by analyzing information on home page discharge history patients Hebei Tumor Hospital, provide scientific basis for prevention treatment cancer.The all discharges, new cases, surgical patients, age, gender, length stay hospitalization cost Hospital from January 2012 December 2019 were retrieved based medical record management...
Mammary Paget's disease (PD) is a rare type of breast cancer. Most cases PD are presented with underlying ductal carcinoma in situ (DCIS) or invasive (IDC). This study aimed to investigate the clinicopathological characteristics and survival outcomes patients.A total 406 patients diagnosed IDC/DCIS at Fudan University Shanghai Cancer Center (FUSCC) were recruited as group, 1218 alone during same period selected non-PD results these two groups compared. The Surveillance, Epidemiology, End...
To investigate the computed tomographic (CT) and pathological features of primary pulmonary sarcomatoid carcinoma (PSC).The clinical data CT images 20 patients with pathologically confirmed PSC were retrospectively analyzed.Solitary mass was identified in 18 multiple masses 2 patients, amounting to 22 masses. There 17 peripheral 5 central masses, including 11 larger than cm. The smooth margin 9 deep lobulation and/or spinous protuberance ill-defined Pleural indentation pleural thickening...
Abstract Objective: to understand the mental resilience and psychosomatic status quo of first-line anti-epidemic medical team members, so as provide a reference basis for mastering health members promoting improvement resilience. Methods: cluster sampling method was used conduct mobile phone questionnaire survey on selected subjects using staff Chinese version scale (Chinese cd-risc). Results: total score 65.40 ± 13.90 points higher than that community. However, tenacity men women (P <...
Ventilator-associated pneumonia (VAP) is still an important cause of morbidity and mortality in patients receiving mechanical ventilation. This research aimed to investigate the genes related VAP potential diagnosis targets.Gene expression profiles data GSE30385 were downloaded from Gene Expression Omnibus, which included 10 samples with without VAP. The differentially expressed (DEGs) between two types identified by limma package functions pathways DEGs predicted Ontology KEGG pathway...