A5108050401- Acute Myeloid Leukemia Research
- Systemic Lupus Erythematosus Research
- Adipose Tissue and Metabolism
- Traditional Chinese Medicine Analysis
- Viral Infections and Vectors
- Health disparities and outcomes
- Liver Disease Diagnosis and Treatment
- Viral Infections and Outbreaks Research
- Acupuncture Treatment Research Studies
- Pain Mechanisms and Treatments
- Climate Change and Health Impacts
- Vitamin D Research Studies
- Pregnancy and Medication Impact
- Gaze Tracking and Assistive Technology
- Stroke Rehabilitation and Recovery
- Diabetes Treatment and Management
- Atherosclerosis and Cardiovascular Diseases
- Liver Disease and Transplantation
- Cancer-related molecular mechanisms research
- Mechanical Circulatory Support Devices
- Cancer, Hypoxia, and Metabolism
- Traditional Chinese Medicine Studies
- Reproductive System and Pregnancy
- Global Health Care Issues
- Chronic Myeloid Leukemia Treatments
China Population and Development Research Center
2019-2025
Peking University
2019-2025
First Affiliated Hospital of Bengbu Medical College
2018-2025
Beijing Academy of Artificial Intelligence
2025
Shandong Freshwater Fisheries Research Institute
2025
Zhengzhou Central Hospital
2025
University of Electronic Science and Technology of China
2017-2024
Shaanxi University of Chinese Medicine
2024
First Affiliated Hospital of Anhui Medical University
2017-2024
Anhui Medical University
2017-2024
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 has become an important public health issue in world. More than 118 000 cases were confirmed around The main clinical manifestations symptoms and occasional gastrointestinal symptoms. However, there is no unified standard for diagnosis treatment of COVID-19. In retrospective analysis, we report nine COVID-19, describe history contact, manifestations, course before, during after treatment.
Here, we aimed to retrospectively analyze the clinical characteristics of 27 patients with severe pneumonia caused by Chlamydia psittaci between January 2019 and April 2021 in southwest China. To this end, collected data on exposure history, symptoms, laboratory examination, imaging characteristics, evolution, etiology, treatment, outcomes suggest a better diagnosis prevention system. Our results showed that metagenomic next-generation sequencing test could provide early diagnosis. All were...
Previous studies showed that prevalence of abdominal obesity among US children and adolescents increased significantly between 1988-1994 2003-2004. However, little is known about recent time trends in since 2003-2004.This study was to provide updated national estimates childhood examine the from 2003 2012.Data were National Health Nutrition Examination Survey (NHANES) conducted during 5 periods (2003-2004, 2005-2006, 2007-2008, 2009-2010, 2011-2012). A total 16,601 aged 2 18 years included....
Oncogenic KRAS plays a crucial role in pancreatic ductal adenocarcinoma (PDAC) development and progression. However, the mechanism has not been clearly elucidated. RKIP is tumor repressor, loss of shown PDAC. Here, we found that expression was inversely correlated with PDAC fresh tissue regardless mutant status. The negative correlation between further confirmed our microarray. overexpression downregulation were associated poor clinical outcomes. Knockdown or cell lines robustly increased...
Abstract Background We previously reported an inverse relationship between B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP), which is associated with the prognosis of gastric cancer (GC). In this study, we further explored microRNA (miRNA) regulatory mechanism Bmi-1 RKIP. Methods Microarray analysis was first carried out to identify miRNA profiles that were differentially expressed in cells overexpressing Bmi-1. Then, miRNAs...
A smart all-hydrogel-based dressing fabricated by a self-healing cross-linking strategy can achieve effective monitoring of wound temperature, mechanical strain and on-demand drug delivery to inhibit bacterial growth in order promote healing.
Sophoridine (SR) has shown the potential to be an antiarrhythmic agent. However, SR's electrophysiological properties and druggability research are relatively inadequate, which limits development of SR as candidate. To facilitate process candidate, we performed integrated studies on in vitro ex vivo gain more comprehensive insights into multi-ion channel blocking effects SR, provided foundation for further drugability safety studies. Firstly, potentials were recorded assessed at cell tissue...
Whether the association between obesity-related anthropometric indices and multimorbidity differs by age among Chinese older adults (aged 65+) is unclear. We aimed to investigate body mass index (BMI), waist circumference (WC) waist-to-hip ratio (WHR) with young-old 65-79) old-old 80+) adults.Cross-sectional population-based study.Shandong province on eastern coast of China.5493 subjects aged 65 years or above.Details sociodemographics, lifestyle characteristics chronic conditions were...
Objective To explore the association between socioeconomic status (SES) and vitamin D deficiency/insufficiency of women childbearing age in rural northern China. Design A population-based, case–control study was conducted. Setting Four counties Henan Province, China from 2009 to 2010. Participants 1151 non-pregnant healthy 18 40 years old. Primary secondary outcome measures Serum 25-hydroxyvitamin (25(OH)D) levels were measured using high-performance liquid chromatography-tandem mass...
Abstract Background While sarcopenia is recognized as a predictor of mortality in cirrhosis, its influence on acute‐on‐chronic liver failure (ACLF) remains uncertain. Despite multiple studies examining the impact short‐term patients with ACLF, sample size these was limited, and their outcomes were inconsistent. Therefore, this study aimed to explore both short‐ long‐term ACLF. Methods This retrospective cohort included 414 ACLF that treated between January 2016 September 2022. Sarcopenia...
Objective The aim of the present study was to evaluate incidences margin involvement, disease relapse, and complications in patients who had undergone conization using an electrosurgical knife (EKC) for cervical intraepithelial neoplasia (CIN) or microinvasive carcinomas (micro-CAs). Materials Methods A retrospective case series analysis performed with a total 1359 underwent EKC Fudan University Shanghai Cancer Center between June 2004 July 2010. Results median age 39 years old (range:...
This study aims to explore the association of anthropometric indices obesity with hypertension in Chinese elderly and its possible gender age differences. A total 7070 adults 60 or older were interviewed a cross-sectional conducted 2017. Anthropometric for each participant measured by using standard methods trained doctoral/master students. We performed two binary logistic regression models examine nine different gender. Lastly, analyses steps stratified age. Comparing individuals without...
Abstract High rate of cardiovascular disease (CVD) has been reported among patients with coronavirus 2019 (COVID-19). Importantly, CVD, as one the comorbidities, could also increase risks severity COVID-19. Here we identified phospholipase A2 group VII (PLA2G7), a well-studied CVD biomarker, hub gene in COVID-19 though an integrated hypothesis-free genomic analysis on nasal swabs (n = 486) from PLA2G7 was further found to be predominantly expressed by proinflammatory macrophages lungs...
Background: Maternal passive smoking and vitamin D deficiency might elevate risk of spontaneous abortion. The study aimed to investigate the association co-exposure with Methods: A population-based case-control was performed among non-smoking women in Henan Province, China, 293 abortion cases 496 liveborn controls term, normal birthweight. Results: Compared without exposure nor deficiency, deficient alone had increased (OR = 1.76, 95%CI: 1.08~2.89; OR 1.73, 1.11~2.69, respectively). even...
Sit-To-Stand (STS) tests are reported as feasible alternatives for the assessment of functional fitness but reliability these in people with coronary artery disease (CAD) has not been reported. This study explored test-retest reliability, convergent and known-groups validity five times, 30-sec 1-min sit-to-stand test (FTSTS test, 30-s STS respectively) patients CAD. The feasibility applying to distinguish level risk cardiovascular events CAD was also investigated.Patients stable performed a...