Li Li

ORCID: 0000-0003-4802-8689
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About
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Research Areas
  • Influenza Virus Research Studies
  • Climate Change and Health Impacts
  • Respiratory viral infections research
  • Air Quality and Health Impacts
  • COVID-19 Clinical Research Studies
  • COVID-19 epidemiological studies
  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • COVID-19 and healthcare impacts
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Global Health Care Issues
  • Pneumonia and Respiratory Infections
  • Long-Term Effects of COVID-19
  • Viral gastroenteritis research and epidemiology
  • Educational Reforms and Innovations
  • Nutritional Studies and Diet
  • Inflammatory Biomarkers in Disease Prognosis
  • Immune Response and Inflammation
  • Thermoregulation and physiological responses
  • Virology and Viral Diseases
  • Heavy Metal Exposure and Toxicity
  • Corneal surgery and disorders
  • Ophthalmology and Visual Impairment Studies
  • COVID-19 diagnosis using AI

Fujian Provincial Hospital
2020-2025

Fujian Medical University
2020-2025

Fuzhou University
2025

University of Alabama at Birmingham
2025

Fred Hutch Cancer Center
2019-2025

Nanjing University of Chinese Medicine
2023-2025

Shenzhen Children's Hospital
2022-2025

Zhengzhou University
2025

Henan Provincial Chest Hospital
2025

Southern Medical University
2014-2024

Background The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Objective To evaluate the risk of serious adverse outcomes in patients with COVID-19 by stratifying comorbidity status. Methods We analysed data from 1590 laboratory confirmed hospitalised 575 hospitals 31 provinces/autonomous regions/provincial municipalities across mainland China between 11 December and January 2020. composite end-points, which consisted admission to an intensive care unit, invasive...

10.1183/13993003.00547-2020 article EN cc-by-nc European Respiratory Journal 2020-03-26

BackgroundThe estimation of influenza-associated excess mortality in countries can help to improve estimates the global burden attributable influenza virus infections. We did a study estimate respiratory mainland China for 2010–11 through 2014–15 seasons.MethodsWe obtained provincial weekly surveillance data and population 161 disease points 31 provinces from Chinese Center Disease Control Prevention years 2005–15. with an annual average rate less than 0·4% between 2005 2015 or 0·3% any...

10.1016/s2468-2667(19)30163-x article EN cc-by-nc-nd The Lancet Public Health 2019-09-01

Abstract We report epidemiologic, laboratory, and clinical findings for 7 patients with 2019 novel coronavirus disease in a 2-family cluster. Our study confirms asymptomatic human-to-human transmission through close contacts familial hospital settings. These might also serve as practical reference diagnosis medical treatment.

10.3201/eid2607.200718 article EN cc-by Emerging infectious diseases 2020-03-30

Abstract Objective To evaluate the spectrum of comorbidities and its impact on clinical outcome in patients with coronavirus disease 2019 (COVID-19). Design Retrospective case studies Setting 575 hospitals 31 province/autonomous regions/provincial municipalities across China Participants 1,590 laboratory-confirmed hospitalized patients. Data were collected from November 21 st , to January 2020. Main outcomes measures Epidemiological variables (in particular, comorbidities) extracted medical...

10.1101/2020.02.25.20027664 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-27

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) moved rapidly through China, and the virus had spread to more than 60 countries infected nearly 90 000 patients by March 5, 2020. Based on data for 72 314 cases of disease 2019 (COVID-19), 14% people have severe disease, 5% critical illness, 2·3% die.1Wu Z McGoogan JM Characteristics important lessons from (COVID-19) outbreak in China: summary a report Chinese Center Disease Control Prevention.JAMA. 2020; (published online Feb...

10.1016/s2213-2600(20)30125-9 article EN other-oa The Lancet Respiratory Medicine 2020-03-17

On September 21, 2009, China began administering vaccines, obtained from 10 different manufacturers, against 2009 pandemic influenza A (H1N1) virus infection in priority populations. We aimed to assess the safety of this vaccination program.We designed a plan for passive surveillance adverse events after immunization with vaccine. Physicians or providers were required report numbers vaccinees and all their local Center Disease Control Prevention (CDC), which then reported data Chinese CDC...

10.1056/nejmoa1008553 article EN New England Journal of Medicine 2011-02-02

Human infection by H7N9 influenza virus was first identified in China March 2013. As of 12 August 2013, a total 135 documented cases with 44 fatalities had been reported. Genetic and laboratory analyses the novel viruses isolated from patients indicate that these possess several polymerase gene mutations previously associated human adaptation potential pandemic capabilities. However, function emergence pathogenicity is not well known. In this study, we demonstrate PB2 E627K mutation, which...

10.1099/vir.0.061721-0 article EN Journal of General Virology 2014-01-07

Preventing suicide is a global imperative. Although the effects of social and individual risk factors have been widely investigated, evidence environmental exposure to air pollution scarce. We investigated ambient on mortality in Guangzhou, China during 2003−2012. A conditional logistic regression analysis with time-stratified case-crossover design was performed assess daily three standard pollutants, including particulate matter less than 10 μm aerodynamic diameter (PM10), sulphur dioxide...

10.1186/s12940-016-0177-1 article EN cc-by Environmental Health 2016-08-30

Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 has become an important public health issue in world. More than 118 000 cases were confirmed around The main clinical manifestations symptoms and occasional gastrointestinal symptoms. However, there is no unified standard for diagnosis treatment of COVID-19. In retrospective analysis, we report nine COVID-19, describe history contact, manifestations, course before, during after treatment.

10.1002/jmv.25755 article EN Journal of Medical Virology 2020-03-12

This study aimed to observe the efficacy of corticosteroids in non-severe COVID-19 pneumonia. A retrospective based on propensity score matching was designed explore effects corticosteroids. Primary outcomes included rate patients who developed severe disease and mortality. Secondary duration fever, virus clearance time, length hospital stay, use antibiotics. total 475 with pneumonia were enrolled, 55 received early, low-dose, short-term therapy, 420 non-corticosteroids therapy. Compared...

10.1007/s40121-020-00332-3 article EN cc-by-nc Infectious Diseases and Therapy 2020-09-02

<bold>Background:</bold> Diabetes correlates with poor prognosis in patients COVID-19, but very few studies have evaluated whether impaired fasting glucose (IFG) is also a risk factor for the outcomes of COVID-19. Here we aimed to examine associations between IFG and diabetes at admission risks complications mortality among <bold>Methods:</bold> In this multicenter retrospective cohort study, enrolled 312 hospitalized COVID-19 from 5 hospitals Wuhan Jan 1 Mar 17, 2020. Clinical information,...

10.3389/fendo.2020.00525 article EN cc-by Frontiers in Endocrinology 2020-07-10

In New York City, the situation of COVID-19 is so serious that it has caused hundreds thousands people to be infected due its strong infectivity. The desired effect wearing masks by public not ideal, though increasingly recommended WHO. order reveal potential mask use, we posed a dynamical model with effective coverage face assess impact use on transmission. We obtained basic reproduction number R0 which determined global dynamics. According implement policies in divided transmission three...

10.1016/j.rinp.2022.105224 article EN cc-by-nc-nd Results in Physics 2022-01-22

This study aimed to develop a nomogram model for early prediction of the severe

10.2147/jir.s447569 article EN cc-by-nc Journal of Inflammation Research 2024-02-01

To investigate the changes in meibomian gland (MG) structure allergic conjunctivitis (AC) patients using an intelligent quantitative analysis algorithm and to explore relationship between these clinical parameters. A total of 252 eyes from with AC 200 normal controls were examined. Infrared meibography was performed non-contact mode Keratograph 5M. MG images analyzed a deep learning-based evaluate length, area, dropout ratio, deformation. Clinical parameters, including tear meniscus height,...

10.3389/fcell.2024.1518154 article EN cc-by Frontiers in Cell and Developmental Biology 2025-01-06

Objective Obesity can contribute to infertility, but the exact relationship between infertility risk and obesity-related measurements like waist-to-height ratio (WHtR), body roundness index (BRI), conicity (CoI), A shape (ABSI) in women is uncertain. We investigated association these indices female infertility. Methods In this cross-sectional study, we used National Health Nutrition Examination Survey data (2013–2018). weighted multivariable logistic regression analysis, receiver operating...

10.1177/03000605251315019 article EN cc-by-nc Journal of International Medical Research 2025-02-01

Preterm birth (PTB) is a major cause of infant morbidity and mortality. The aim this study was to investigate the effect vaginal microbiota metabolites on outcome pregnant women. In study, total 127 women provided written informed consent prior enrollment in accordance with approved institutional guidelines, but only 45 pregnancies met experimental requirements, then blood cervical fluid (CVF) samples were collected before delivery (at second week after cerclage). Pregnant PTB exhibited high...

10.3389/fcimb.2025.1444028 article EN cc-by Frontiers in Cellular and Infection Microbiology 2025-02-11

Abstract Background In the past two decades east African highlands have experienced several major malaria epidemics. Currently there is a renewed interest in exploring possibility of anopheline larval control through environmental management or larvicide as an additional means reducing transmission Africa. This study examined landscape determinants mosquito habitats and usefulness remote sensing identifying these western Kenya highlands. Methods Panchromatic aerial photos, Ikonos Landsat...

10.1186/1475-2875-5-13 article EN cc-by Malaria Journal 2006-02-16
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