A5037147534- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Respiratory Support and Mechanisms
- Influenza Virus Research Studies
- Hepatitis B Virus Studies
- Vaccine Coverage and Hesitancy
- Disaster Response and Management
- Cytomegalovirus and herpesvirus research
- Cardiac, Anesthesia and Surgical Outcomes
- Viral gastroenteritis research and epidemiology
- Ultrasound in Clinical Applications
- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Respiratory viral infections research
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Virology and Viral Diseases
- Plasma Applications and Diagnostics
- Mosquito-borne diseases and control
- Virus-based gene therapy research
- Immunodeficiency and Autoimmune Disorders
- Herpesvirus Infections and Treatments
- Ferroptosis and cancer prognosis
- Nosocomial Infections in ICU
Chongqing Medical University
2004-2025
People's Hospital of Bishan District
2021-2025
Southern Medical University
2022-2025
Peking Union Medical College Hospital
2013-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Jiamusi University
2018-2024
Shenyang Institute of Computing Technology (China)
2024
Chinese Academy of Sciences
2012-2024
Princeton University
2021-2024
Sun Yat-sen University
2014-2024
Recent studies have described regional differences in the electrophysiology and pharmacology of ventricular myocardium canine, feline, rat, guinea pig, human hearts. In this study, we use standard microelectrode whole-cell patch-clamp techniques to examine characteristics action potential delayed rectifier K+ current (IK) epicardial, M region (deep subepicardial midmyocardial), endocardial cells isolated from canine left ventricle. Cells displayed much longer durations (APDs) at slow rates....
Purpose Under Medicare's Coverage with Evidence Development policy, positron emission tomography (PET)/computed (CT) and PET became covered services for previously noncovered cancer indications if prospective registry data were collected. The National Oncologic Registry (NOPR) was developed to meet these coverage requirements assess how affects care decisions. Methods NOPR collected questionnaire from referring physicians on intended patient management before after PET. After 1 year, the...
Abstract BACKGROUND: The study was conducted to determine whether radiofrequency ablation (RFA) can safely reduce pain from osseous metastatic disease. METHODS: single‐arm prospective trial included patients with a single painful bone metastasis unremitting score >50 on scale of 0‐100. Percutaneous computed tomography‐guided RFA the temperatures >60°C performed. Endpoints were toxicity and effects before at 2 weeks, 1 month, 3 months after RFA. RESULTS: Fifty‐five completed Grade...
The study was established to inquire into the protective effect of HIF-1α (Hypoxia-inducible factor-1α)/ BNIP3(Bcl-2/adenovirus E1B 19-kDa interacting protein) signal path-induced-autophagy during myocardial ischemia/ reperfusion (I/R) and oxygen-glucose deprivation/recovery (OGD/R) injury in heart-derived H9C2 cells as well its potential underlying mechanism.Immediate I/R SD (Spraque Dawley) rats cytotoxicity OGD/R on with without inhibitors or agonists BNIP3 were evaluated. Expression...
Abstract Background Hypoxia has long been considered as a hallmark of solid tumors and is closely associated with tumor progression. Circular RNAs (circRNAs) have identified critical modulator in various cancers. However, the connections between hypoxia circRNAs are largely unknown. Methods Here, we investigated expression profile breast cancer (BC) MCF-7 cells under normoxia using microarray. We novel hypoxia-responsive circRNA named circWSB1, whose pattern, potential diagnostic value...
On September 21, 2009, China began administering vaccines, obtained from 10 different manufacturers, against 2009 pandemic influenza A (H1N1) virus infection in priority populations. We aimed to assess the safety of this vaccination program.We designed a plan for passive surveillance adverse events after immunization with vaccine. Physicians or providers were required report numbers vaccinees and all their local Center Disease Control Prevention (CDC), which then reported data Chinese CDC...
Cuproptosis, a newly discovered form of cell death, is regulated by protein lipoylation and related to mitochondrial metabolism. However, further research needed determine how the cuproptosis-related gene ferredoxin 1 (FDX1) affects tumor immune response its prognostic significance in clear renal carcinoma (ccRCC).The Cancer Genome Atlas was used screen for FDX1 expression ccRCC healthy tissue samples. The results were validated using Gene Expression Omnibus Human Protein Atlas....
The interferon inducible protein 16 (IFI16) is a prominent sensor of nuclear pathogenic DNA, initiating innate immune signaling and suppressing viral transcription. However, little known about mechanisms that initiate IFI16 antiviral functions or its regulation within the host DNA-filled nucleus. Here, we provide in vitro vivo evidence to establish undergoes liquid-liquid phase separation (LLPS) nucleated by DNA. binding DNA initiates LLPS induction cytokines during herpes simplex virus type...
The last case of infection with wild-type poliovirus indigenous to China was reported in 1994, and certified as a poliomyelitis-free region 2000. In 2011, an outbreak imported occurred the province Xinjiang.We conducted investigation guide response outbreak, performed sequence analysis type 1 capsid protein VP1 determine source, carried out serologic coverage surveys assess risk viral propagation. Surveillance for acute flaccid paralysis intensified enhance ascertainment.Between July 3...
Background: China reduced hepatitis B virus (HBV) infection by 90% among children under 5 years old with safe and effective vaccines (HepB). In December 2013, this success was threatened widespread media reports of infant deaths following HepB administration. Seventeen one case anaphylactic shock HBV vaccination had been reported. Methods: We conducted a telephone survey to measure parental confidence in eleven provinces at four points time; reviewed maternal status use for newborns birth...
The functional interaction landscape of HSV-1 infection uncovers a link between immune sensing and the DNA damage response.
Low temperature plasmas (LTPs) enable to create a highly reactive environment at near ambient temperatures due the energetic electrons with typical kinetic energies in range of 1 10 eV (1 = 11600K), which are being used applications ranging from plasma etching electronic chips and additive manufacturing plasma-assisted combustion. LTPs core many advanced technologies. Without LTPs, conveniences modern society would simply not exist. New continuously proposed. Researchers facing grand...
Nowadays, electromagnetic pollution caused by electronic devices is gradually becoming a concern. Moreover, as the frequency of from mainly in range 2–10 GHz, design microwave-absorbing materials for this has become hot issue. To tackle issue, core-shell structured hexagonal boron nitride (h-BN) @polyaniline (PAn) composites have been proposed to construct heterogeneous materials. Firstly, h-BN exfoliated, and hydroxyl functionalized produce hydroxy (OH-BN), which enhances its polarization...
Salinity is one of the major abiotic stresses affecting plant productivity but surprisingly, a thorough understanding salt-responsive networks responsible for sustaining growth and maintaining crop yield remains significant challenge. Rice suspension culture cells (SCCs), single cell type, were evaluated as model system they provide ready source homogenous type avoid complications multicellular tissue types in planta. A combination performance, transcriptional analyses using known...
The "third-generation" cooking oil based drug, named plasma activated (PAO), is produced in cheap olive by a single-step, room temperature, energy-efficient, and environment-friendly dry plasma-enabled process. streamer-surface discharge generates abundant energetic species, atomic oxygen at the plasma–oil interface. otherwise challenging dissociation of C═C double bonds species oxidation generated key mechanism to produce H2O2 active carboxylic acid PAO. It shown that peroxide value PAO are...
In volumetric brain imaging analysis, volumes of structures are typically assumed to be proportional or linearly related intracranial volume (ICV). However, evidence abounds that many have power law relationships with ICV. To take this relationship into account in we propose a based method-the power-proportion method-for ICV correction. The performance the new method is demonstrated using data from PREDICT-HD study.
Triggering receptor expressed by myeloid cells (TREM-1) is an amplifier of inflammatory responses triggered bacterial or fungal infection.Soluble TREM-1 (sTREM-1) expression was found to be upregulated in sepsis-associated acute kidney injury (SA-AKI) and predicted a potential biomarker.However, the mechanism remains unclear.The human kidney-2 (HK-2) cell line treated with lipopolysaccharide (LPS) used examine roles apoptosis autophagy.A viability assay employed assess number viable as...
We hypothesized that not all patients with appreciably recruited lung tissue during a recruitment maneuver (RM) show significant improvement of oxygenation. In the present study, we combined electrical impedance tomography (EIT) oxygenation measurements to examine discrepancies ventilation and perfusion versus after RM. A 2-minute RM (20 cm H2O positive end-expiratory pressure [PEEP] + 20 control) was prospectively conducted in acute respiratory distress syndrome from January 2014 December...