A5101591330- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- COVID-19 Clinical Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- MicroRNA in disease regulation
- COVID-19 diagnosis using AI
- Ferroptosis and cancer prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- HER2/EGFR in Cancer Research
- Airway Management and Intubation Techniques
- Chronic Myeloid Leukemia Treatments
- Long-Term Effects of COVID-19
- Colorectal and Anal Carcinomas
- Immune Cell Function and Interaction
- Esophageal Cancer Research and Treatment
Tianjin Medical University
2025
Tianjin Medical University Eye Hospital
2025
Dalian Medical University
2017-2024
First Affiliated Hospital of Dalian Medical University
2017-2024
First Affiliated Hospital of Guangzhou Medical University
2018-2024
Guangzhou Medical University
2018-2024
Chengdu University of Traditional Chinese Medicine
2024
State Key Laboratory of Respiratory Disease
2018-2024
National Clinical Research
2020-2024
Beijing University of Chinese Medicine
2024
Background The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Objective To evaluate the risk of serious adverse outcomes in patients with COVID-19 by stratifying comorbidity status. Methods We analysed data from 1590 laboratory confirmed hospitalised 575 hospitals 31 provinces/autonomous regions/provincial municipalities across mainland China between 11 December and January 2020. composite end-points, which consisted admission to an intensive care unit, invasive...
Early identification of patients with novel coronavirus disease 2019 (COVID-19) who may develop critical illness is great importance and aid in delivering proper treatment optimizing use resources.To validate a clinical score at hospital admission for predicting which COVID-19 will based on nationwide cohort China.Collaborating the National Health Commission China, we established retrospective from 575 hospitals 31 provincial administrative regions as January 31, 2020. Epidemiological,...
During the outbreak of coronavirus disease 2019 (COVID-19), consistent and considerable differences in severity mortality rate patients treated Hubei province compared to those other parts China have been observed. We sought compare clinical characteristics outcomes being inside outside province, explore factors underlying these differences.
Abstract The sudden deterioration of patients with novel coronavirus disease 2019 (COVID-19) into critical illness is major concern. It imperative to identify these early. We show that a deep learning-based survival model can predict the risk COVID-19 developing based on clinical characteristics at admission. develop this using cohort 1590 from 575 medical centers, internal validation performance concordance index 0.894 further validate three separate cohorts Wuhan, Hubei and Guangdong...
Abstract Objective To evaluate the spectrum of comorbidities and its impact on clinical outcome in patients with coronavirus disease 2019 (COVID-19). Design Retrospective case studies Setting 575 hospitals 31 province/autonomous regions/provincial municipalities across China Participants 1,590 laboratory-confirmed hospitalized patients. Data were collected from November 21 st , to January 2020. Main outcomes measures Epidemiological variables (in particular, comorbidities) extracted medical...
Estrogen receptor β (ERβ) plays critical roles in thyroid cancer progression. However, its role stem cell maintenance remains elusive. Here, we report that ERβ is overexpressed papillary cells (PTCSCs), whereas ablation of decreases stemness-related factors expression, diminishes ALDH+ populations, and suppresses sphere formation ability tumor growth. Screening estrogen-responsive lncRNAs PTC spheroid cells, find lncRNA-H19 highly expressed PTCSCs tissue specimens, which correlated with poor...
The protein tyrosine phosphatase PTP 1B, which is encoded by PTPN 1, a ubiquitously expressed nonreceptor phosphatase. 1B has long been known to negatively regulate insulin and leptin receptor signalling. Recently, it was reported be aberrantly in cancer cells function as an important oncogene. In this study, we found that levels are dramatically increased breast (BC) tissues promotes the proliferation, suppresses apoptosis, of both HER 2‐positive triple‐negative BC cell lines....