Zhong Chen

ORCID: 0000-0003-0116-2653
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Research Areas
  • COVID-19 Clinical Research Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Chronic Disease Management Strategies
  • COVID-19 and healthcare impacts
  • Long-Term Effects of COVID-19
  • Liver Disease Diagnosis and Treatment
  • Cancer, Lipids, and Metabolism
  • Cytokine Signaling Pathways and Interactions
  • COVID-19 epidemiological studies
  • COVID-19 and Mental Health
  • SARS-CoV-2 and COVID-19 Research
  • Galectins and Cancer Biology
  • Respiratory Support and Mechanisms
  • Cancer Mechanisms and Therapy
  • COVID-19 diagnosis using AI
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Chronic Kidney Disease and Diabetes
  • Sepsis Diagnosis and Treatment
  • Whipple's Disease and Interleukins

University of Nottingham Ningbo China
2024

Meizhou City People's Hospital
2024

Sanya Central Hospital
2018-2020

Nantong University
2019

Affiliated Hospital of Nantong University
2019

Zhongda Hospital Southeast University
2013

Background The coronavirus disease 2019 (COVID-19) outbreak is evolving rapidly worldwide. Objective To evaluate the risk of serious adverse outcomes in patients with COVID-19 by stratifying comorbidity status. Methods We analysed data from 1590 laboratory confirmed hospitalised 575 hospitals 31 provinces/autonomous regions/provincial municipalities across mainland China between 11 December and January 2020. composite end-points, which consisted admission to an intensive care unit, invasive...

10.1183/13993003.00547-2020 article EN cc-by-nc European Respiratory Journal 2020-03-26

Abstract Background Since December 2019, acute respiratory disease (ARD) due to 2019 novel coronavirus (2019-nCoV) emerged in Wuhan city and rapidly spread throughout China. We sought delineate the clinical characteristics of these cases. Methods extracted data on 1,099 patients with laboratory-confirmed 2019-nCoV ARD from 552 hospitals 31 provinces/provincial municipalities through January 29 th , 2020. Results The median age was 47.0 years, 41.90% were females. Only 1.18% had a direct...

10.1101/2020.02.06.20020974 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-09

The novel coronavirus disease 2019 (COVID-19) has become a global health emergency. cumulative number of new confirmed cases and deaths are still increasing out China. Independent predicted factors associated with fatal outcomes remain uncertain.The goal the current study was to investigate potential risk from COVID-19 through multivariate Cox regression analysis nomogram model.A retrospective cohort 1,590 hospitalized patients throughout China established. prognostic effects variables,...

10.1016/j.chest.2020.04.010 article EN other-oa CHEST Journal 2020-04-15

Abstract Objective To evaluate the spectrum of comorbidities and its impact on clinical outcome in patients with coronavirus disease 2019 (COVID-19). Design Retrospective case studies Setting 575 hospitals 31 province/autonomous regions/provincial municipalities across China Participants 1,590 laboratory-confirmed hospitalized patients. Data were collected from November 21 st , to January 2020. Main outcomes measures Epidemiological variables (in particular, comorbidities) extracted medical...

10.1101/2020.02.25.20027664 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-27

Background: Whether repeat surgical resection (RSR) or radiofrequency ablation (RFA) is a better option for recurrent hepatocellular carcinoma (HCC) after primary HCC remains controversial. This study was to investigate the clinical efficacy of RSR versus RFA in treatment at Barcelona Clinic Liver Cancer (BCLC) stage 0/A HCC. Methods: The patients treated by (n=57) (n=51) BCLC Affiliated Hospital Nantong University and Third Second Military Medical from January 2008 March 2018 were included....

10.21037/tcr.2019.06.11 article EN Translational Cancer Research 2019-08-01

Lung carcinoma is the most common cancer and cause of deaths among both males females in China. Previously, genetic variants located gene untranslated region have been well established as interfering factors mRNA translation confirmed playing critical roles lung oncogenesis. However, correlation between polymorphisms 3' risk less reported China Han population. In this study, 3'-untranslated IL-16, CYP24A1, FBN1 were determined 322 patients 384 healthy controls with usage Sequenom MassARRAY....

10.1155/2018/8305745 article EN BioMed Research International 2018-12-24

10.11569/wcjd.v23.i21.3344 article EN Shijie huaren xiaohua zazhi 2015-01-01
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