A5049706456- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Organometallic Complex Synthesis and Catalysis
- Synthesis and characterization of novel inorganic/organometallic compounds
- Crystallography and molecular interactions
- Protein Structure and Dynamics
- Nutrition, Genetics, and Disease
- Wnt/β-catenin signaling in development and cancer
- Magnetism in coordination complexes
- Coordination Chemistry and Organometallics
- Inorganic Fluorides and Related Compounds
- Organoboron and organosilicon chemistry
- Enzyme Structure and Function
- Inorganic Chemistry and Materials
- Porphyrin and Phthalocyanine Chemistry
- BRCA gene mutations in cancer
- Cancer-related gene regulation
- Advanced Glycation End Products research
- Synthesis and biological activity
- Metal complexes synthesis and properties
- Phosphodiesterase function and regulation
- Chemical Synthesis and Analysis
- Asymmetric Hydrogenation and Catalysis
- Enzyme Production and Characterization
- Lipid Membrane Structure and Behavior
University of Bologna
1993-2024
Latvijas Organiskās Sintēzes Institūts
2020-2024
Institute of Organic Synthesis
2023-2024
Italian Institute of Technology
2013-2022
Center for Nano Science and Technology
2012-2022
Cell Biotech (South Korea)
2020
Mylan (South Africa)
2016
Mylan (Switzerland)
2015
Politecnico di Milano
2011-2014
Istituto Nazionale di Documentazione Innovazione e Ricerca Educativa
2014
Carbon nano-onions (CNOs) are an exciting class of carbon nanomaterials, which have recently demonstrated a facile cell-penetration capability. In the present work, highly fluorescent boron dipyrromethene (BODIPY) dyes were covalently attached to surface CNOs. The introduction this new nanomaterial-based imaging platform, made CNOs and BODIPY fluorophores, allows for exploration synergetic effects between two building blocks elucidation its performance in biological applications. high...
With Brookhart type α-diimine Ni(II) based catalysts, it is highly challenging to tune polymers branching level and branch-type distribution, which in turn strongly affects thermal mechanical properties, through the aryl ortho-positions modification, while maintaining high turnover frequencies (TOFs). Herein, we are interested performing a systematic investigation on polymerization of 1-octene, 1-decene, 1-octadecene catalyzed by series nickel(II) complexes with methyl ligand backbone...
Photonic crystal-based biosensors hold great promise as low-cost devices for real-time monitoring of a variety biotargets, example, bacterial contaminants in food. Here, we report the proof-of-concept new colorimetric sensor contamination, which is based on novel hybrid plasmonic–photonic device. Our system consists layer silver, plasmonic metal exhibiting well-known bioactivity, top one-dimensional photonic crystal. We attribute bioresponsivity to formation polarization charges at...
Lithium (2,6-diisopropylphenyl)(trimethylsilyl)amide (2,6-iPr2C6H3N(SiMe3)Li) reacts with MCl4 (M = Zr, Hf) in a 2:1 molar ratio to give [{2,6-iPr2C6H3N(SiMe3)}2MCl2] (1a, M Zr; 1b, and (C5Me5)MCl3 (1:1) [(C5Me5){2,6-iPr2C6H3N(SiMe3)}MCl2] (2a, 2b, Hf). Further reaction of the dichlorides (1a,b, 2a,b) Me3SnF leads corresponding difluorides [{2,6-iPr2C6H3N(SiMe3)}2MF2] (3a, 3b, [(C5Me5){2,6-iPr2C6H3N(SiMe3)}MF2] (4a, 4b, The compounds 1−4 were investigated as potential catalysts for...
Many of the genes that comprise vertebrate adaptive immune system are conserved across wide evolutionary time scales. Most notably, homologs mammalian MHC gene family have been found in virtually all jawed vertebrates, including sharks, bony fishes, reptiles, and birds. The CD1 antigen-presenting molecules related to class I but evolved bind present lipid antigens T cells. Here, we describe two highly divergent nonclassical chicken (Gallus gallus) sequence homology proteins. One expresses a...
Abstract A series of π‐extended distyryl‐substituted boron dipyrromethene (BODIPY) derivatives with intense far‐red/near‐infrared (NIR) fluorescence was synthesized and characterized, a view to enhance the dye’s performance for labeling. An enhanced brightness achieved by introduction two methyl substituents in meso positions on phenyl group BODIPY molecule; these resulted increased structural rigidity. Solid‐state observed one derivatives. The terminal bromo substituent allows subsequent...
A current challenge in materials science and biotechnology is to express a specific controlled functionality on the large interfacial area of nanostructured material create smart biohybrid systems for targeted applications. Here, we report system featuring poly(vinyl alcohol) as supporting synthetic polymer bovine serum albumin biofunctional element. The optimal processing conditions produce these self-standing composite membranes are determined, composition distribution bioactive agent...
A major problem of current biomedical implants is the bacterial colonization and subsequent biofilm formation, which seriously affects their functioning can lead to serious post-surgical complications. Intensive efforts have been directed toward development novel technologies that prevent while requiring minimal antibiotics doses. To this end, biocompatible materials with intrinsic antifouling capabilities are in high demand. Silk fibroin, widely employed biotechnology, represents an...
Abstract The reactions of [(Me 3 Si) CLi2thf] with Me 2 MCl (M = Al, Ga) afford the mixed trialkylmetallanes ‐CAlMe ·thf] ( 1 ) and CGaMe in high yields. coordinated THF molecule compound can be removed by sublimation vacuo to yield solvent‐free product ‐CGaMe ] ). Hydrolysis one equivalent water at 0°C gives trimeric hydroxide [{(Me CGaMe(μ‐OH)} 4 ), while reaction two equivalents room temperature yields unusually stable gallium hydroxide‐water complex CGaMe(OH)(μ‐OH)MeGaC(SiMe H O·2thf] 6...
Two crystal polymorphs of a thiophene–phenylene hexamer with bulky terminal substituents are characterized by different molecular conformations and parallel versus herringbone packing. Irrespective their similar emissive spectra common H-aggregate features, evidenced structure analysis confirmed solid-phase excited-state first-principles calculations, luminescence is relatively high and, for one form, nearly double than that the other. Interaromatic packing energy contributions established...
The stereoselective synthesis of highly functionalized 1,2,3-trisubstituted cyclopropanes 1 and 2, starting from readily available furans 3 or N-protected pyrrole 4, is described. Furthermore, exceptionally high diastereocontrol in agreement with the Felkin−Anh model was observed for addition nucleophiles to title compounds.