- Neurofibromatosis and Schwannoma Cases
- Advanced Multi-Objective Optimization Algorithms
- Cancer Mechanisms and Therapy
- Topology Optimization in Engineering
- Composite Structure Analysis and Optimization
- Neuroblastoma Research and Treatments
- Domain Adaptation and Few-Shot Learning
- Wnt/β-catenin signaling in development and cancer
- Mathematical and Theoretical Epidemiology and Ecology Models
- Probiotics and Fermented Foods
- Clostridium difficile and Clostridium perfringens research
- Engineering and Test Systems
- Vasculitis and related conditions
- Kidney Stones and Urolithiasis Treatments
- Phagocytosis and Immune Regulation
- Evolutionary Game Theory and Cooperation
- Food Allergy and Anaphylaxis Research
- Pediatric health and respiratory diseases
- Herbal Medicine Research Studies
- Dermatologic Treatments and Research
- Immune cells in cancer
- Cell Adhesion Molecules Research
- Curcumin's Biomedical Applications
- Ureteral procedures and complications
- Pediatric Urology and Nephrology Studies
Lanzhou University Second Hospital
2023-2025
Northwestern Polytechnical University
2025
Lanzhou University
2021-2025
Second Hospital of Hebei Medical University
2012-2024
Hebei Medical University
2012-2024
Dalian University of Technology
2020-2023
Huazhong University of Science and Technology
2020
Nanchang University
2018
South China University of Technology
2008
The anti-fungus mechanisms and curative effects of cinnamon oil pogostemon complexes towards intestinal Candida infections were investigated. We measured the minimal inhibitory concentration (MIC) values against using proportionally-diluted test-tube medium, examined evolution morphology structures albicans scanning electronic microscopy (SEM) transmission (TEM). found that average MIC fungi 0.064 mg/mL (cinnamon oil), 0.032 (pogostemon oil) for albicans, 0.129 tropicalis, krusei. SEM...
Asymmetry is omnipresent in human society and nature the reasons causing asymmetry are multiple. To think about impact of asymmetries on cooperation systems, we focus a typical model great asymmetric traits---the boxed pigs game---and extended one-to-one interaction to population. We consider payoff spatial structure two populations space. Our results have shown that almost equal abundance strength kills cooperative behavior. The single increase either strength-asymmetry or...
Abstract Background Henoch–Schonlein purpura (HSP) is a systemic small vessel vasculitis that mainly caused by IgA1‐type immune complex deposition. Advanced oxidation protein products (AOPPs) are specific markers of oxidation. Objective To explore the role AOPPs in pathogenesis HSP. Methods There 51 HSP patients who were divided into four subgroups: (i) skin type – 20 cases; (ii) joint 8 (iii) abdominal 12 (iv) renal 11 and 18 healthy volunteers enrolled as controls. The serum levels Gd‐IgA1...
3096 Background: Neurofibromatosis type 1(NF1) is an autosomal dominant tumor predisposition syndrome characterized by NF1 gene variants, resulting in over-activation of the RAS pathway. Plexiform neurofibroma (PN) benign tumors that arise from nerve tissue and are a hallmark feature NF1. They typically grow along nerves cause disfigurement, pain, other complications depending on their location size. FCN-159, highly potent selective inhibitor MEK1/2 targeting inhibition pathway, holds...
Large multimodal language models (MLLMs) have revolutionized natural processing and visual understanding, but often contain outdated or inaccurate information. Current knowledge editing evaluations are limited in scope potentially biased, focusing on narrow tasks failing to assess the impact in-domain samples. To address these issues, we introduce ComprehendEdit, a comprehensive benchmark comprising eight diverse from multiple datasets. We propose two novel metrics: Knowledge Generalization...
Continual Test-Time Adaptation (CTTA) involves adapting a pre-trained source model to continually changing unsupervised target domains. In this paper, we systematically analyze the challenges of task: online environment, nature, and risks error accumulation catastrophic forgetting under continual domain shifts. To address these challenges, reshape data buffering organizing mechanism for CTTA. We propose an {uncertainty-aware approach} identify {and aggregate} significant samples with high...
Rolling element bearing is one of the most critical components in rotating machines. Effectively predicting Remaining Useful Life (RUL) can prevent occurrence sudden equipment failure. In this paper, time-domain features vibration signals are extracted and then these fused. order to establish a more accurate prediction model, health state divided into stage degradation by 3σ principles. stage, Box-Cox transformation method applied on data. The parameter λ sample number curve further...
Objective To provide imaging anatomy basis for percutaneous nephrolithotomy (PCNL) by measuring relative displacement and changes in anatomical position of kidney colon under the prone low-oblique supine positions. Methods Forty-six patients scheduled PCNL underwent 64-slice spiral CT scan low-arch oblique before PCNL.The horizontal distance colon, from analog puncturing line, between were measured compared 2 positions. Results The line positions as follows, left (26.56±15.36)...
3103 Background: Neurofibromatosis type 1 (NF1) is a common autosomal dominant genetic disease characterized by elevated RAS-mitogen activated protein kinase (MAPK) signaling that causes tumors to grow along the nerves. There currently no medical cure for adult patients (pts). Plexiform neurofibromas (PN) present in 20-50% of NF1 pts and may cause serious complications. FCN-159 highly potent anti-tumorigenic agent functions via selective inhibition MEK1/2. This study assessed safety efficacy...
10023 Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disease characterized by multiple progressive tumor and non-tumor manifestations, with abnormal activating MAPK pathway. Plexiform neurofibromas (PN) presents in 20-50% of NF1 patients (pts) may cause serious complications. Selumetinib was approved for pediatric pts NF1-related PN US EU, but therapeutic options remain limited China. FCN-159 a highly potent selective anti-tumorigenic inhibitor MEK1/2,...
Objective To investigate the effect of N-myc downstream regulated gene 2(NDRG2) on apoptosis bladder cancer cells by regulating signal transducer and activator transcription 3(STAT3) signaling pathway. Methods The expression level NDRG2 in human cell BIU-87 immortalized SV-HUC-1 was detected Western blot. over vector empty control (pcDNA3.1), siRNA-NDRG2, siRNA were transfected into cells.After 48 h, NDRG2, Cleaved caspase 3, STAT3, p-STAT3, JAK2, p-JAK2 blot , proliferation measured...