A5082861592- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Nutritional Studies and Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Child Nutrition and Water Access
- Obesity, Physical Activity, Diet
- Long-Term Effects of COVID-19
- Diabetes Management and Research
- COVID-19 Clinical Research Studies
- Child Nutrition and Feeding Issues
- Birth, Development, and Health
- Phytoestrogen effects and research
- Food Security and Health in Diverse Populations
- Consumer Attitudes and Food Labeling
- Metabolism, Diabetes, and Cancer
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Gastroesophageal reflux and treatments
- Cardiovascular Health and Risk Factors
- Liver Disease Diagnosis and Treatment
- COVID-19 and Mental Health
- Dysphagia Assessment and Management
- SARS-CoV-2 and COVID-19 Research
- Public Health and Nutrition
- Gut microbiota and health
- Digestive system and related health
Mahidol University
2021-2024
Siriraj Hospital
2021-2024
National Science and Technology Development Agency
2022
Abstract Background Food frequency questionnaires (FFQ) are a useful dietary assessment tool to determine relationships between diet and non-communicable diseases (NCDs). Our purpose was validate semiquantitative FFQ (semi-FFQ) for Thais at risk of metabolic syndrome (MS). Methods The researchers identified 345 men women aged 30–65 years who were eligible the study. Ninety-four participants finally enrolled (54 in “urine-collection not-required” group 40 “urine collection” group). They asked...
Protein-energy malnutrition still impacts children's growth and development. We investigated the prolonged effects of egg supplementation on microbiota in primary school children. For this study, 8-14-year-old students (51.5% F) six rural schools Thailand were randomly assigned into three groups: (1) whole (WE), consuming 10 additional eggs/week (n = 238) 238); (2) protein substitute (PS), yolk-free substitutes equivalent to 200); (3) control group (C, 197)). The outcomes measured at week 0,...
This study aimed to compare newly developed diabetes-specific complete smoothie formulas with a standard nutritional formula (DSNF) regarding their effects on glucose homeostasis, insulin levels, and lipid metabolism in obese type 2 diabetes (T2DM) patients. We conducted randomized, double-blind, crossover 41 T2DM participants two formulas, soy-based regular (SM) modified carbohydrate content (SMMC), the DSNF, Glucerna. Glycemic responses were assessed after randomly consumed 300...
Background Increasing levels of poor glycaemic control among Thai patients with type 2 diabetes mellitus (T2DM) motivated us to compare T2DM care between urban and suburban primary units (PCUs), identify gaps in care, significant factors that may influence strategies enhance the quality clinical outcomes this population. Methods We conducted a cross-sectional study involving 2160 treated at four PCUs from 2019 2021, comprising one three facilities. Using mixed effects logistic regression, we...
Many patients develop post-acute COVID syndrome (long (LC)). We compared the immune response of LC and individuals with post-COVID full recovery (HC) during Omicron pandemic. Two hundred ninety-two confirmed infections from January to May 2022 were enrolled. observed anti-SARS-CoV-2 receptor-binding domain immunoglobulin G, surrogate virus neutralization test, T cell subsets, neutralizing antibodies against Wuhan, BA.1, BA.5 viruses (NeuT). NeuT was markedly reduced BA.1 in HC groups, while...
The gut microbiota exert a profound influence on human health and metabolism, with microbial metabolites playing pivotal role in shaping host physiology. This study investigated the impact of prolonged egg supplementation insulin-like growth factor 1 (IGF-1) circulating short-chain fatty acids (SCFAs). In subset cluster-randomized trial, participants aged 8-14 years were randomly assigned into three groups: (1) Whole Egg (WE)-consuming 10 additional eggs per week [n = 24], (2) Protein...
Abstract Background Dysphagia is a common problem in older adults that can lead to nutritional deficiencies. Nutrition support an alternative therapy, specifically manufactured for the individuals at risk of dysphagia. This study aimed develop four high protein (23-34% energy ratio) and low carbohydrate (25-38% smoothie formulas (white sesame (WS) vs. white (WSLC) black (BSLC) chicken shitake (CS); 1 kcal/ml) people with dysphagia assess their effect on swallowing capacity compared completed...
Background The study of non-communicable diseases (NCDs) in a developing country like Thailand has rarely been conducted long-term cohorts, especially among the working-age population. We aim to assess prevalence and incidence risk factors their associations underlying NCDs, type-2 diabetes mellitus (T2DM) healthcare workers enrolled Siriraj Health (SIH) cohort. Methods SIH was designed as longitudinal cohort at hospital, Thailand. A total 5,011 participants (77% women) were recruited...
Abstract Background High-protein, low-carbohydrate enteral formulas (EN) can improve glycemic control in individuals for with type 2 diabetes (T2DM) ambulatory care. This study aimed to compare newly developed diabetes-specific complete smoothie a standard nutritional formula (DSNF) regarding their effects on glucose homeostasis, insulin levels, and lipid metabolism obese T2DM patients. Methods We conducted randomized, double-blind, crossover 41 participants. Two were from locally available...
Abstract Background: The low-carbohydrate-ketogenic diet, an effective strategy to address metabolic syndrome (MetS) and obesity has been concerns about high fat consumption on atherogenic lipoproteins. This study aimed compare the Asian ketogenic diet (AKD), which incorporates balanced protein intake from foods, with a low-caloric (BLC) in individuals diagnosed MetS. Methods: A 52-week randomized clinical trial included three parallel groups: AKD increased whole egg (Yolk-KD, aged 40.9 ±...
ABSTRACT BACKGROUND In a number of patients, post-acute COVID syndrome develops after acute infection with severe respiratory coronavirus 2 (SARS-CoV-2) (Long [LC]). Here, we examined the immune responses and clinical characteristics individuals LC compared to age- gender-matched healthy recovered (HC) during Omicron pandemic. Immune following BNT162b2 (Pfizer) booster are also determined. METHODS This retrospective cohort study included 292 patients (LC, 158; HC, 134) confirmed have...
Abstract Background The study of non-communicable diseases (NCDs) in a developing country like Thailand has rarely conducted long-term cohort, especially working-age population. We aim to assess the prevalence and incidence risk factors their associations underlying NCDs, type-2 diabetes mellitus (T2DM) among healthcare workers enrolled Siriraj Health (SIH) cohort. Methods SIH was designed as longitudinal cohort at hospital, Thailand. A total 5,011 participants (77% Female) were recruited...
We aimed to determine long-term effects of egg supplementation on growth, blood lipoproteins, proteins, nutritional status, and microbiota in primary school children. A randomized controlled, cluster study was performed at 6 rural schools Central, Eastern, Western Thailand. 635 students (8–14 years old) were recruited into the study. Subjects randomly assigned 3 groups, based weight for age: 1) Whole eggs (WE) - consume 10 additional per week [n = 238] 2) Egg substitute (ES) yolk-free...
We aimed to study the effect of an Asian ketogenic diet with increased egg consumption on anthropometries, glucose, and cholesterol homeostasis in people metabolic syndrome. compared changes parameters between a (carbohydrate < 10% total calories) whole intakes (Yolk KD) or yolk-free white supplementation (White balanced controlled energy (C). This included 4-week run phase, 12-week intervention follow up phase at week-36. Subjects were monitored for biochemistries including oral glucose...
Summary Background Protein-energy malnutrition is still problematic worldwide. It directly impacts growth and development, especially in children. We investigated the long-term effects of egg supplementation on growth, biochemical indices, microbiota primary school Methods A randomized controlled cluster study was carried out six rural schools Thailand. Participants were randomly assigned into three groups: 1) whole (WE) – consuming 10 additional eggs/week [n = 238], 2) protein substitute...
Abstract Background Food frequency questionnaires (FFQ) are a useful dietary assessment tool to determine relationships between diet and non-communicable diseases (NCDs). Our purpose was validate semiquantitative FFQ (semi-FFQ) for Thais at risk of metabolic syndrome (MS). Methods The study identified 345 men women aged 30 65 years were enrolled invited participate in data collection 4 weeks. They asked maintain 4-day food record partook semi-FFQ interview during week 4. Urine samples...