A5004441832- Trauma and Emergency Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Abdominal Trauma and Injuries
- Total Knee Arthroplasty Outcomes
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Orthopedic Infections and Treatments
- Rheumatoid Arthritis Research and Therapies
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Pelvic and Acetabular Injuries
- Sports injuries and prevention
- Osteoarthritis Treatment and Mechanisms
- Gout, Hyperuricemia, Uric Acid
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Bone fractures and treatments
- COVID-19 and healthcare impacts
- Drug Transport and Resistance Mechanisms
- Emergency and Acute Care Studies
- Hip and Femur Fractures
- Trauma Management and Diagnosis
- Disaster Response and Management
University of Szeged
2020-2024
There is growing evidence regarding the role of mitochondrial dysfunction in osteoarthritis (OA) and rheumatoid arthritis (RA). However, quantitative comparison synovial derangements these main forms missing. A prospective clinical study was conducted on adult patients undergoing knee surgery. Patients were allocated into RA OA groups based disease-specific scores, while without served as controls. Synovial samples subjected to high-resolution respirometry analyze functions. From total 814...
<b><i>Purpose:</i></b> The aim was to examine the predictive value of hypovolemic shock classification currently accepted by Advanced Trauma Life Support (ATLS) program over previous one, which used only vital signs (VS) for patient allocation. primary outcome 30-day mortality; as secondary outcome, heart rate (HR), systolic blood pressure (SBP), Glasgow Coma Scale (GCS) and base deficit (BD) data were compared investigated in terms mortality prediction....
To compare the outcomes of a 6-month-long accelerated rehabilitation with 12-month-long rehabilitation. There is no consensus on optimal duration after anterior cruciate ligament reconstruction (ACLR). Trends in past decades have shifted towards programs, often resulting return to play (RTP) at 4-6 months, postoperatively. However, longer cycles recently experienced renaissance due greater understanding graft remodeling.Adult athletes who underwent ACLR between 2015 and 2018 by same surgeon...
Introduction Early recognition and effective treatment of internal bleeding impose a cardinal challenge for trauma teams. The reduction the superior mesenteric artery (SMA) blood flow is among first compensatory responses to loss, thus being promising candidate as diagnostic tool occult haemorrhage. Unfortunately, methods monitoring SMA have not been elaborated date. Nevertheless, animal experiments suggest that exhaled methane (CH 4 ) levels correspond perfusion. We hypothesise real-time...
Despite their clinical effectiveness, a growing body of evidence has shown that many classes antibiotics lead to mitochondrial dysfunction. Ceftriaxone and Rifaximin are first choice perioperative in gastrointestinal surgery targeting fundamental processes intestinal bacteria; however, may also have negative consequences for the host cells. In this study, we investigated direct effect on functions vitro, together with impact ileum, colon liver tissue. Additionally, microbiome was studied...
Abstract Background: The aim was to compare the predictive performance of current, extended (VS+BD) Advanced Trauma Life Support (ATLS) classification for hypovolaemic shock over previous, vital sign (VS)-based with respect mortality outcomes. We also studied prognostic values heart rate (HR), systolic blood pressure (SBP), Glasgow Coma Scale (GCS) and base deficit (BD). Methods: present study is a retrospective analysis at level I trauma centre between 11 July 2014 September 2019. patients...
Hemorrhage control often poses a great challenge for clinicians due to trauma-induced coagulopathy (TIC). The pathogenesis of TIC is not completely revealed; however, growing evidence attributes central role altered platelet biology. activation thrombocytes and subsequent clot formation are highly energetic processes being tied mitochondrial activity, the inhibition electron transport chain (ETC) impedes on thrombogenesis, suggesting potential mitochondria in TIC. Our present study protocol...
In the absence of effective treatment options, recent SARS-CoV2 pandemic poses a great challenge to health and social sectors worldwide. Hereby, we would like share our proposals in hope that it will prove helpful for colleagues this difficult time. The present recommendations are based on opinion experts as well experience group traumatologists directly involved organization traumatology wards. reassignment healthcare personnel, separation potentially infected patients different levels...
Purpose: There is growing evidence for the role of mitochondrial dysfunction in osteoarthritis (OA) and rheumatoid arthritis (RA). However, quantitative comparison derangements these main forms clinical settings missing. Therefore, our aim was to characterize altered functions synovial membranes OA RA patients. Methods: Synovial tissue samples were taken intraoperatively subjected high-resolution respirometry (Oxygraph-2k, Oroboros Instruments, Austria) analyze oxygen consumption. The...
A baleseti ellátás paradigmaváltásait az utóbbi évtizedekben jellemzően nemzeti vagy nemzetközi trauma regiszterek, illetve nagyszámú kohorszok elemzése előzte meg. adatbázisok alkalmat nyújtanak hipotézisek felállítására és validálására; protokollok tervezésére effektivitásuk kontrolljára; a betegellátás minőségellenőrzésére; intézmények, régiók, országok teljesítményének összehasonlításra; akár prevenciós célokra is. Hazánk I-es szintű centrumaiban magas színvonalú polytrauma zajlik, ennek...