Moslem Javidan

ORCID: 0000-0002-5638-4512
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About
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Research Areas
  • Reproductive System and Pregnancy
  • Ovarian function and disorders
  • Endometriosis Research and Treatment
  • Immune Cell Function and Interaction
  • Genomics, phytochemicals, and oxidative stress
  • Phagocytosis and Immune Regulation
  • Endoplasmic Reticulum Stress and Disease
  • Sperm and Testicular Function
  • Hypothalamic control of reproductive hormones
  • Autophagy in Disease and Therapy
  • Biochemical and Structural Characterization
  • Inflammatory Bowel Disease
  • Assisted Reproductive Technology and Twin Pregnancy
  • Uterine Myomas and Treatments
  • Protein Hydrolysis and Bioactive Peptides
  • Insect Utilization and Effects
  • Immunotherapy and Immune Responses
  • Ovarian cancer diagnosis and treatment
  • Air Quality and Health Impacts
  • RNA regulation and disease
  • T-cell and B-cell Immunology
  • Acute Lymphoblastic Leukemia research

Ahvaz Jundishapur University of Medical Sciences
2024

Tehran University of Medical Sciences
2021-2023

Cancer is still considered a lethal disease worldwide and the patients’ quality of life affected by major side effects treatments including post-surgery complications, chemo-, radiation therapy. Recently, new therapeutic approaches were globally for increasing conventional cancer therapy efficacy decreasing adverse effects. Bioactive peptides obtained from plant animal sources have drawn increased attention because their potential as complementary This review presents contemporary...

10.3389/fimmu.2024.1310443 article EN cc-by Frontiers in Immunology 2024-01-24

Abstract Breast cancer is significantly influenced by endoplasmic reticulum (ER) stress, impacting both its initiation and progression. When cells experience an accumulation of misfolded or unfolded proteins, they activate the protein response (UPR) to restore cellular balance. In breast cancer, UPR frequently triggered due challenging conditions within tumors. The has a dual impact on cancer. On one hand, it can contribute tumor growth enhancing cell survival resistance programmed death in...

10.1186/s12935-024-03296-3 article EN cc-by Cancer Cell International 2024-03-11

Endometriosis (EMT) is a chronic inflammatory disease characterized by the presence and growth of endometrial-like glandular epithelial stromal cells outside uterus. Natural Killer (NK) cell dysfunction/exhaustion has been shown in patients with EMT. In this case-control study, we compared frequency exhausted PD-1 or TIM-3 positive NK peripheral blood (PB) peritoneal fluid (PF) women advanced endometriosis to control fertile women. PB PF were collected from aged 25–40 who underwent...

10.1016/j.heliyon.2023.e23294 article EN cc-by-nc-nd Heliyon 2023-12-10

Abstract Aims Impaired implantation due to the reduced endometrial receptivity considers an etiology for infertility in polycystic ovary syndrome (PCOS). In this context, we aimed compare expression of interleukin 10 ( Il10 ), homeobox A10 Hoxa10 signal transducer and activator transcription 3 Stat3 β3‐integrin Itgb3 ) embryo site a prenatally‐androgenized rat model PCOS before during gestation. Materials Methods was created by injection testosterone prenatally. The uterine tissues were...

10.1111/aji.13702 article EN American Journal of Reproductive Immunology 2023-04-16

Crohn's disease (CD) is a chronic inflammatory without specific cause. Inflammation in these patients can disturb the oxidants/antioxidants balance and results oxidative stress that plays destructive role. This study aimed to evaluate gene expression of sod1, sod2, cat, nrf2 gp91phox CD before after Azathioprine (Aza) consumption.Peripheral bloodmononuclear cells (PBMCs) were separated from (n= 15, mean age = 33.6 ± 1.8) treatment with Aza healthy controls 31.5 1.2). The levels measured...

10.1080/13510002.2021.1915665 article EN cc-by Redox Report 2021-01-01
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