Chieh‐Yu Chang

ORCID: 0000-0002-5638-482X
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About
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Research Areas
  • Catalytic C–H Functionalization Methods
  • Pelvic floor disorders treatments
  • Alkaloids: synthesis and pharmacology
  • Traditional and Medicinal Uses of Annonaceae
  • Chemical Synthesis and Analysis
  • Sulfur-Based Synthesis Techniques
  • Synthesis and Catalytic Reactions
  • Synthetic Organic Chemistry Methods
  • Catalytic Cross-Coupling Reactions
  • Algebraic structures and combinatorial models
  • Chemical Synthesis and Reactions
  • Urinary Bladder and Prostate Research
  • Magnetism in coordination complexes
  • Phytoestrogen effects and research
  • Phytochemical compounds biological activities
  • Cancer Cells and Metastasis
  • TGF-β signaling in diseases
  • Diamond and Carbon-based Materials Research
  • Chemical synthesis and alkaloids
  • Thin-Film Transistor Technologies
  • Asymmetric Hydrogenation and Catalysis
  • Metal-Catalyzed Oxygenation Mechanisms
  • Anorectal Disease Treatments and Outcomes
  • Algebraic Geometry and Number Theory
  • Copper Interconnects and Reliability

University of Florida
2024

Kaohsiung Municipal Hsiao-Kang Hospital
2024

Kaohsiung Medical University
2024

Kaohsiung Medical University Chung-Ho Memorial Hospital
2024

National Yang Ming Chiao Tung University
1997-2022

Institute of Biomedical Sciences, Academia Sinica
2018

National Tsing Hua University
2018

A highly regio- and enantioselective hydrosulfonylation using commercially available sodium sulfinates is reported, providing the first direct asymmetric rhodium-catalyzed of allenes/alkynes to synthesize chiral allylic sulfones. Ligand screening studies demonstrated indispensable role C1-symmetric P,N-ligand (Rax,S,S)-StackPhim for achieving both high regioselecitivity (>20:1) enantioselectivity (up 97% ee). Notably, operationally simple method mild conditions allow rapid preparation...

10.1021/jacs.4c05629 article EN Journal of the American Chemical Society 2024-06-14

The N1-selective allylation of indoles with allylic alcohols has been accomplished by synergistic functions palladium catalysts and titanium tetraisopropoxide.

10.1039/c8cc09817d article EN Chemical Communications 2019-01-01

<title>Abstract</title> Pelvic organ prolapse (POP) often coexists with stress urinary incontinence (SUI), posing challenges in surgical management. De novo SUI post-surgery remains unpredictable, prompting this study to explore ultrasound's role assessing de after transvaginal mesh (TVM) surgery. A retrospective analysis of 696 women undergoing TVM surgery revealed a 36.9% incidence SUI. Specific ultrasound parameters, such as proximal urethral rotational angle and levator gap during...

10.21203/rs.3.rs-4596667/v1 preprint EN Research Square (Research Square) 2024-07-04

A method is reported for the catalytic direct coupling of allylic alcohols and nitroalkanes. In allylation process, synergistic action palladium complexes titanium(IV) alkoxide facilitates formation nitronate π-allylpalladium intermediate. cases reluctant allylations, typically with sterically demanding nitroalkanes, we found addition substoichiometric amount DBU greatly desired transformation. We also accomplished a total synthesis (±)-adalinine through homoallyl nitroalkane derived from...

10.1021/acs.joc.8b00710 article EN The Journal of Organic Chemistry 2018-05-16

We formulate and prove a log-algebraicity theorem for arbitrary rank Drinfeld modules defined over the polynomial ring F_q[theta]. This generalizes results of Anderson one case. As an application we show that certain special values Goss L-functions are linear forms in logarithms transcendental.

10.1112/jlms.12098 article EN Journal of the London Mathematical Society 2018-01-08

Abstract Described is a concise route to (±)‐taiwaniaquinol B. The 6‐5‐6‐fused ring system was constructed by sequencing Fries rearrangement and photo‐Nazarov cyclization. application of photoirradiation conditions found be crucial for promoting the key electrocyclization mitigating competing oxo‐Michael pathway.

10.1002/ajoc.202100721 article EN Asian Journal of Organic Chemistry 2021-12-22

Objectives: Stress urinary incontinence (SUI) negatively affects the quality of life and sexual function in women. This study aimed to evaluate efficacy radiofrequency (RF) therapy reducing SUI symptoms its impact on function. Methods: Thirty-four women with were enrolled underwent a single RF treatment session using Viveve® System (Viveve Medical Inc., USA) parameters 90 J/cm2 220 pulses per hour. Assessments at baseline 6 months post included perineal ultrasound personal interviews lower...

10.3390/biomedicines12102288 article EN cc-by Biomedicines 2024-10-09

A concise total synthesis of racemic mersicarpine is achieved featuring an application a 6- exo-trig radical cyclization 2-indolyl radical.

10.1039/d2ob00620k article EN Organic & Biomolecular Chemistry 2022-01-01

Abstract Described is a formal synthesis of racemic schulzeines B and C that intercepts intermediates developed by Gurjar co‐workers. The synthetic sequence features an annulative coupling ketimine acrylic acid enabling the construction benzoquinolizidine nucleus in highly convergent manner. We also examined continuous‐flow version thermal aza‐annulation, which proved less practical as compared to batch processes.

10.1002/jccs.202000216 article EN Journal of the Chinese Chemical Society 2020-08-20

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at glance that was extracted from about 100 leading journals. To access of an article which published elsewhere, please select “Full Text” option. The original trackable via the “References”

10.1002/chin.199721266 article EN ChemInform 1997-05-20
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