A5007956897- Tuberculosis Research and Epidemiology
- Global Maternal and Child Health
- Food Security and Health in Diverse Populations
- Child Nutrition and Water Access
- Pneumonia and Respiratory Infections
- Antibiotics Pharmacokinetics and Efficacy
- Diagnosis and treatment of tuberculosis
- Vaccine Coverage and Hesitancy
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- HIV/AIDS Impact and Responses
- Child and Adolescent Health
- Respiratory viral infections research
- Influenza Virus Research Studies
- Cystic Fibrosis Research Advances
- Mobile Health and mHealth Applications
- Amoebic Infections and Treatments
- Ultrasound in Clinical Applications
- Child Nutrition and Feeding Issues
- Hepatitis Viruses Studies and Epidemiology
- ICT in Developing Communities
- Disaster Management and Resilience
Kamuzu Central Hospital
2025
Michigan State University
2025
University of Wisconsin–Madison
2016-2024
University of Malawi
2023
Pediatrics and Genetics
2023
Baylor College of Medicine
2020-2021
Texas Children's Hospital
2020-2021
Improving childhood vaccination coverage and timeliness is a key health policy objective in many developing countries such as Uganda. Of the factors known to influence uptake of immunizations under resourced settings, parents' understanding perception has largely been overlooked. The aims this study were survey mothers' knowledge attitudes towards then determine if these variables correlate with timely their children. From September December 2013, we conducted cross-sectional 1,000 parous...
BACKGROUND AND OBJECTIVE Addressing adverse social determinants of health is an upstream approach to potentially improve child outcomes and equity. We aimed determine if systematically screening referring for needs in hospitalized pediatric patients increased families’ enrollment publicly available resources. METHODS Randomized controlled trial at a large urban children’s hospital enrolled English-speaking caregivers 0 36 months age on the general pediatrics service from June 2016 July 2017....
Each year 25 000-32 000 children develop rifampicin- or multidrug-resistant tuberculosis (RR/MDR-TB), and many more require preventive treatment. Levofloxacin is a key component of RR/MDR-TB treatment prevention, but the existing pharmacokinetic data in have not yet been comprehensively summarized. We aimed to characterize levofloxacin pharmacokinetics through an individual patient meta-analysis available studies determine optimal dosing children.
Population-based data on the epidemiology of nontuberculosis mycobacterial (NTM) infections are limited, particularly with respect to variation in NTM infection among racial groups and socioeconomic strata. Wisconsin is one a handful states where disease notifiable, allowing large, population-based analyses this state.
Severe acute malnutrition (SAM) is a major cause of childhood mortality in resource-limited settings. The relationship between clinical factors and adherence to the 'WHO 10 Steps' children with SAM not fully understood.Data from an ongoing prospective observational cohort study assessing admission characteristics, management patterns outcome aged 6-36 months admitted tertiary hospital Malawi September 2018 2019 were analysed. Data clerks independently collected data patients' charts....
Daptomycin is a common treatment for serious infections caused by gram-positive bacteria in adult patients; however, data regarding its safety and efficacy the pediatric population are limited. This was retrospective chart review of adverse reactions outcomes associated with daptomycin use children <13 years old who received at least 1 dose daptomycin. At 147 patients. Seventy-two patients 5 or more days. New-onset loose stools on initiation were reported 14 (9.5%) patients, elevations...
The WHO recommends that children and adolescents living with HIV (CALHIV) complete TB symptom screening at every clinical encounter but evidence supporting this recommendation is limited. We evaluated the performance of recommended in six high-burden TB/HIV countries.Retrospective longitudinal cohort.We extracted data from electronic medical records CALHIV receiving care clinics Botswana, Eswatini, Lesotho, Malawi, Tanzania, Uganda January 2014 to June 2017. defined incident cases as those...
The epidemiology of nontuberculous mycobacteria (NTM) infections in the pediatric population is not well described. We estimated incidence NTM infection Wisconsin children and adolescents, frequency type caused by different pathogens. Associations between race/ethnicity social disadvantage, respectively, were also investigated.
Point-of-care ultrasound (POCUS) to diagnose tuberculosis (TB) was assessed in 131 children under 5 years old hospitalized with severe acute malnutrition. Of these, 23% had confirmed or unconfirmed TB and 5% were HIV-infected. There no POCUS findings associated diagnosis. visualization quality satisfactory for 65% examination acceptability “good” 52%.
Welcome to Annals of Global Health,Annals Health is a peer-reviewed, fully open access, online journal dedicated publishing high quality articles all aspects global health. The journal's mission advance health, promote research, and foster the prevention treatment disease worldwide. Its goals are improve health well-being people, equity, wise stewardship earth's environment. latest impact factor 3.64.Annals supported by Program for Public Common Good at Boston College. It was founded in 1934...
This prospective cohort study from Malawi updates our understanding of the burden bacterial infections and drug resistance in children <5 years hospitalized with severe acute malnutrition. Urinary tract infection was diagnosed 20% bacteremia 10%. Resistance to first second-line antibiotics occurred >1/3 bacteria isolated.
Background/Objectives: Common Variable Immunodeficiency Disease (CVID) and other immunodeficiencies can present in subtle variable ways. Whether or not a genetic lesion be identified, there are well understood biomarkers that quantitatively describe how severe deficiency is. Here we discuss two possible ranking systems, CD4/CD8 T cell ratios Immune Health Grades, such data maybe applicable to some immunodeficiencies. Methods: This is systematic review, but identify papers relating with...
During the COVID-19 pandemic, a home ventilator was donated to tertiary-care hospital in Malawi support adults with respiratory failure. As pandemic waned, this reallocated paediatric ward and, an effort help girl aged 8 years life-threatening pneumonia, staff used mask. The were untrained on and confused it continuous positive airway pressure machine, resulting inadvertent use of volume-targeted support.
Severe acute malnutrition (SAM) is common in low-income countries and associated with high mortality young children. To improve recognition management of SAM a tertiary hospital Malawi. The impact multifaceted quality improvement interventions process measures pertaining to the identification was assessed. Interventions included focused training for clinical staff, reporting mobile phone-based group messaging enhanced communication. This initiative on children aged 6-36 months admitted...
Abstract Background Invasive infections caused by gram-positive bacteria are common in pediatric patients and can be challenging to treat. Daptomycin is a lipopeptide antibiotic with activity against adults it alternative first line treatments for complicated skin soft tissue infections, orthopedic endocarditis, bacteremia. Data on the safety of daptomycin population, particularly infants young children, very limited. The aim this study was describe adverse reactions associated use children....
BACKGROUND: The World Health Organization (WHO) estimates tuberculosis (TB) accounted for 40,000 deaths in children living with HIV 2017. Early detection and treatment of TB reduces mortality adolescents (CALHIV). Despite limited evidence, the WHO recommends that CALHIV are actively screened symptoms at every clinical encounter order to improve case detection. As more access care …