A5050797998- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Multiple Myeloma Research and Treatments
- Kruppel-like factors research
- Complementary and Alternative Medicine Studies
- Protein Degradation and Inhibitors
- Cancer survivorship and care
- Cancer Treatment and Pharmacology
- Childhood Cancer Survivors' Quality of Life
- Chronic Lymphocytic Leukemia Research
- Nutritional Studies and Diet
- Nutrition, Genetics, and Disease
- Medicinal Plants and Bioactive Compounds
- CAR-T cell therapy research
- Cancer Mechanisms and Therapy
- Herbal Medicine Research Studies
- Lung Cancer Research Studies
- Hemoglobinopathies and Related Disorders
- Advances in Oncology and Radiotherapy
- Economic and Financial Impacts of Cancer
- Advanced Breast Cancer Therapies
- Quinazolinone synthesis and applications
- Hormonal Regulation and Hypertension
City of Hope
2025
University of Arizona
2018-2024
University of Arizona Cancer Center
2019-2024
Mayo Clinic in Arizona
2013-2022
Palmetto Hematology Oncology
2022
Mayo Clinic Hospital
2016-2018
Mayo Clinic in Florida
2016-2018
WinnMed
2016-2018
Mayo Clinic
2013-2015
Weatherford College
2013
In patients with newly diagnosed multiple myeloma, the effect of adding autologous stem-cell transplantation (ASCT) to triplet therapy (lenalidomide, bortezomib, and dexamethasone [RVD]), followed by lenalidomide maintenance until disease progression, is unknown.In this phase 3 trial, adults (18 65 years age) symptomatic myeloma received one cycle RVD. We randomly assigned these patients, in a 1:1 ratio, receive two additional RVD cycles plus mobilization, either five (the RVD-alone group)...
Abstract Allogeneic hematopoietic cell transplantation (HCT) is the only curative therapy for myelofibrosis (MF). In this large multicenter retrospective study, overall survival (OS) in MF patients treated with allogeneic HCT (551 patients) and without (non-HCT) (1377 was analyzed Cox proportional hazards model. Survival analysis stratified by Dynamic International Prognostic Scoring System (DIPSS) revealed that first year of treatment arm assignment, due to upfront risk transplant-related...
INTRODUCTION ASCO and the Society for Integrative Oncology have collaborated to develop guidelines application of integrative approaches in management anxiety, depression, fatigue use cannabinoids cannabis patients with cancer. These provide evidence-based recommendations improve outcomes quality life by enhancing conventional cancer treatment modalities. METHODS All studies that informed guideline were reviewed an Expert Panel which was made up a patient advocate, methodologist, oncology...
The Philadelphia negative myeloproliferative neoplasms, including polycythemia vera, essential thrombocythemia, and myelofibrosis, are associated with substantial vascular transformative complications. Standard therapy for high-risk disease, particularly in patients that have failed initial therapy, remains controversial. Non-pegylated interferon has previously been shown to be effective controlling erythrocytosis, thrombocytosis thrombotic complications, but was found poor tolerability...
Myeloproliferative neoplasm (MPN) patients suffer from significant symptoms, inflammation and reduced quality of life. Yoga improves these outcomes in other cancers, but this hasn't been demonstrated MPNs. The purpose study was to: (1) explore the limited efficacy (does program show promise success) a 12-week online yoga intervention among MPN on symptom burden life (2) determine feasibility (practicality: to what extent measure can be carried out) remotely collecting inflammatory...
Plasma cell leukemia (PCL) is a rare and aggressive plasma disorder with short survival duration despite the use of novel therapeutics. PCL remains an understudied disease for which there no current standard care treatment. Knowledge on optimal drug sequencing, including role timing hematopoietic stem transplant as primary salvage therapy needed. We conducted large retrospective analysis 153 patients, using new definition ≥ 5% circulating cells, clinical features treatment outcomes across...
Patients with myeloproliferative neoplasms (MPNs) face chronic symptom burden. Online assessment studies allow for recruitment of large numbers motivated patients, but patient self-selection can lead to sampling bias. This study evaluated how gender representativeness in MPN surveys and trials impacted score mean estimates, using data from 4825 survey respondents 291 trial participants MPNs. The showed that men participated at a rate roughly 50% less than what would be expected based on...
Myeloproliferative neoplasms (MPNs) are rare hematological malignancies with a significant symptom burden often left unresolved despite recent advances in pharmacological therapy. Yoga is nonpharmacological strategy that has been shown to improve symptoms other cancers and may be effective for improving MPN patients. Online yoga helps address many of the commonly reported barriers cancer patients in-person interventions make more accessible MPNs. An exploration patient perceptions...
Abstract Myeloproliferative neoplasms (MPNs) are characterized by significant symptom burden. Integrative medicine (IM) offers unique management strategies. This study describes IM interventions utilized MPN patients and the association with burden, quality of life, depression, fatigue adjusted for lifestyle confounders. were surveyed online utilization, burden (MPN‐Symptom Assessment Form Total Symptom Score), depression (Patient Health Questionnaire), (Brief Fatigue Inventory), a single...
8014 Background: Despite the use of novel induction regimens, stem cell transplantation (SCT), and maintenance therapy, plasma leukemia (PCL) remains a challenging disease with dismal prognosis. Currently, there is no agreed standard care management for PCL. We conducted multicenter retrospective analysis clinical presentation, treatment, outcomes 150 patients Methods: Data diagnosed pPCL or sPCL between 01/2010 01/2021 were entered into study-specific REDCap database from 7 different U.S....
Myeloproliferative neoplasms (MPNs) are a group of myeloid malignancies associated with significant symptom burden. Despite pharmacological advances in therapies, inadequate management MPN symptoms results reduced quality life.This study aims to determine the feasibility 12-week global wellness mobile app intervention decreasing The University Arizona Andrew Weil Center for Integrative Medicine's app, My Wellness Coach (MWC), guides patients improve their health and well-being through...