A5060031426- Sarcoma Diagnosis and Treatment
- Bone and Joint Diseases
- Osteoarthritis Treatment and Mechanisms
- Bone Tumor Diagnosis and Treatments
- Piezoelectric Actuators and Control
- Radiomics and Machine Learning in Medical Imaging
- Lower Extremity Biomechanics and Pathologies
- MRI in cancer diagnosis
- Soft Robotics and Applications
- Extracellular vesicles in disease
- Pickering emulsions and particle stabilization
- Metal complexes synthesis and properties
- Water Quality Monitoring and Analysis
- Crystallography and molecular interactions
- Musculoskeletal synovial abnormalities and treatments
- Water Quality Monitoring Technologies
- Iterative Learning Control Systems
- Robotic Mechanisms and Dynamics
- Surfactants and Colloidal Systems
- Cancer-related molecular mechanisms research
- Infrared Thermography in Medicine
- Hydrogen embrittlement and corrosion behaviors in metals
- Wireless Power Transfer Systems
- Magnetic Bearings and Levitation Dynamics
- Vascular Malformations Diagnosis and Treatment
Shanghai Jiao Tong University
2016-2025
Shanghai Ninth People's Hospital
2020-2025
Wuhan University
2025
The University of Texas MD Anderson Cancer Center
2023
Viva Biotech (China)
2023
Southeast University
2022-2023
Hebei University of Technology
2022
Shanghai Sixth People's Hospital
2016-2019
Jilin University
2012
Sichuan University
2010
This study aimed to develop a predictive model detect osteoporosis using radiomic features from lumbar spine computed tomography (CT) images.A total of 133 patients were included in this retrospective study, 41 men and 92 women, with mean age 65.45 ± 9.82 years (range: 31-94 years); 53 had normal bone mineral density, 32 osteopenia, 48 osteoporosis. For each patient, the L1-L4 vertebrae on CT images automatically segmented SenseCare defined as regions interest (ROIs). In total, 1,197...
The approach for estimating biomass in non-contact, free-swimming fish has encountered difficulties such as body occlusion, bending, non-orthogonal angle, and low efficiency. To address these issues, this study had combined posture recognition (using deep learning technology) with estimation (utilizing stereo vision the first time, developing a fast, precise fully automatic system. improved single-stage target detection algorithm significantly direct extraction of high-quality images moving...
Dedifferentiated chondrosarcoma is a rare, highly malignant tumor with poor survival. There are many confusing issues concerning the imaging feature that can facilitate early diagnosis and factors might be related to outcomes.Twenty-three patients dedifferentiated confirmed by pathology were retrospectively reviewed from 2008 2015. The patients' clinical information, images radiographs (n = 17), CT 19), MRI histological features, treatment prognosis analyzed.There 12 males 11 females, mean...
Osteoarthritis treatment remains a significant clinical challenge. Quercetin, natural flavonoid with anti-inflammatory and antiapoptotic properties, might be utilized to treat OA. However, poor water solubility short joint retention duration limit its bioavailability translation applications. A one-step self-assembly method was fabricate quercetin-loaded zeolitic imidazolate framework-8 (Qu@ZIF-8) nanoparticles using zinc ions, 2-methylimidazole, quercetin. In vitro tests showed that...
Smoking-related osteoporosis (SROP) is characterized by reduced bone mass, primarily due to the accumulation of tobacco-derived toxins. This study demonstrates activation ferroptosis and reactive oxygen species (ROS)-related pathways in marrow mesenchymal stem cells (BMSCs) SROP mice. Here, we integrated genetic engineering bone-targeting peptide modification develop innovative engineered exosomes. Using techniques, introduced α-1,3-fucosyltransferase 6 (Fut6), a key protein involved...
BACKGROUND Tenosynovial giant cell tumor (TGCT) is a rare, benign, yet aggressive, lesion, usually involving bursa or the tendon sheath. Spinal TGCT quite rare. Its appearance on imaging can mimic other aggressive diseases, including of bone, metastatic disease, and osteoblastoma, thus posing diagnostic dilemma. We present new pathologically confirmed case localized arising from cervical spine facet joint describe its computed tomography (CT) magnetic resonance (MRI) findings to enhance...
The long-distance oil pipeline in the R-K region of Chad has experienced frequent failures heat-shrink sleeves, significantly impacting normal production oilfield. Therefore, a systematic study soil corrosion behaviour pipelines after sleeve damage is essential before implementing targeted anti-corrosion measures to prevent and control corrosion. Through sample composition analysis, electrochemical testing, immersion experiments on crude specified area Chad, as well morphology analysis...
To develop a magnetic resonance imaging (MRI)-based radiomics predictive model for the identification of knee osteoarthritis (OA), based on tibial and femoral subchondral bone, compare with trabecular structural parameter-based model.Eighty-eight consecutive knees were scanned 3T MRI scored using Knee Scores (MOAKS), in which 56 diagnosed to have OA. The modality sagittal three-dimensional balanced fast-field echo sequence (3D BFFE) was used image bone. Four parameters (bone volume fraction...
Abstract Acquired resistance is a barrier to cetuximab efficacy in patients with head and neck squamous cell carcinoma (HNSCC). Secreted phosphoprotein 1 (SPP1) involved various biological processes, including immune responses, cancer progression, prognosis many cancers, while little known HNSCC. Bioinformatics methods were used identify candidate genes further vivo vitro experiments performed examine validate the function of SPP1. We found that SPP1 was upregulated has been have an...
Objective: To determine whether diffusion kurtosis imaging (DKI) is effective in monitoring tumor response to neoadjuvant chemotherapy patients with osteosarcoma.Materials and Methods: Twenty-nine osteosarcoma (20 men 9 women; mean age, 17.6 ± 7.8 years) who had undergone magnetic resonance (MRI) DKI before after were included.Tumor volume, apparent coefficient (ADC), diffusivity (MD), (MK), change ratio (ΔX) between preand post-treatment calculated.Based on histologic response, the divided...
Osteoarthritis (OA) is now increasingly recognized as being related to the whole joint instead of cartilage alone. In particular, importance subchondral bone in OA pathogenesis has drawn a lot interest. The aim this study investigate microstructural features two femoral condyles human knee osteoarthritis. Eighty subjects were enrolled our and divided into three groups: without (group 0), mild 1), severe 2). Sagittal 3D Balanced Fast Field Echo (3D–FFE) images obtained by 3T MRI quantify...
// Chenglei Liu 1 , Yawen Tang 3 Mei Li Qiong Jiao 2 Huizhen Zhang Qingcheng Yang and Weiwu Yao Department of Radiology, Shanghai Tong University Affiliated Sixth People’s Hospital, Shanghai, China Pathology, Orthopedics, Correspondence to: Yao, email: Yang, Keywords : giant cell tumor, multicentric, bone imaging Received June 09, 2016 Accepted October 26, Published November 03, Abstract Multicentric tumor the (MGCT) is a rare entity whose radiographic, pathological biological features...
Background The importance of subchondral bone in the pathogenesis osteoarthritis (OA) has drawn interest. Purpose To investigate subregional trabecular microstructural features and to determine relationship between cartilage osteoarthritic human knee. Study Type Prospective study. Subjects In all, 92 knees were enrolled divided into three groups: without OA, mild severe OA. Sequence A sagittal 3D balanced fast field echo (3D B‐FFE) sequence FatSat (3D‐FFE) at 3T MRI. Assessment 12 sites knee...
Heteroaromatic stacking interactions are important in drug binding, supramolecular chemistry, and materials science, making protein–ligand model systems of these considerable interest. Here we studied 30 congeneric ligands that each present a distinct heteroarene for between tyrosine residues at the dimer interface procaspase-6. Complex X-ray crystal structures 10 analogs showed geometries were well conserved, while high-accuracy computations energy was correlated with predicted overall...
Automatic segmentation of knee cartilage and quantification parameters are crucial for the early detection treatment osteoarthritis (OA). The aim this study was to develop an automatic method three-dimensional water-selective (3D_WATS) magnetic resonance imaging (MRI) conduct morphometry susceptibility measurements such as thickness, volume, values OA assessment.Sixty-five consecutively sampled subjects, who had undergone health checks at our hospital, were enrolled in cross-sectional...
Chondrosarcomas arise from the lateral pelvis; however, midline chondrosarcomas (10%) display similar imaging features to chordoma, causing a diagnostic challenge. This study aims determine accuracy of apparent diffusion coefficient (ADC)-based radiomic and two novel indices for differentiating sacral chordomas chondrosarcomas.
Background: Computed tomography (CT) imaging is the most important and common means of detecting diagnosing pelvic bone tumors. While phantoms with sufficient flexibility anatomical realism are useful in CT research, using has been difficult for tumors because tumors' relatively large size highly variable shape. By combining medical 3D printing technology fresh tumor specimens, this study aimed to design such a hybrid phantom, test its properties, demonstrate usefulness optimizing protocols....
Background . The accurate prediction of prognosis is key to prompt therapy adjustment. purpose our study was investigate the efficacy diffusion kurtosis imaging (DKI) in predicting progression-free survival (PFS) and overall (OS) osteosarcoma patients with preoperative chemotherapy. Methods Thirty who underwent DKI before after chemotherapy, followed by tumor resection, were retrospectively enrolled. grouped into good responders (GRs) poor (PRs). Kaplan-Meier log-rank test used for analysis....