A5043927669- Nutritional Studies and Diet
- Fatty Acid Research and Health
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Lipoproteins and Cardiovascular Health
- Cholesterol and Lipid Metabolism
- Vitamin D Research Studies
- Cancer, Lipids, and Metabolism
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Ginkgo biloba and Cashew Applications
- Lipid metabolism and disorders
- Antioxidant Activity and Oxidative Stress
- Sodium Intake and Health
- Folate and B Vitamins Research
- Eicosanoids and Hypertension Pharmacology
- Diabetes and associated disorders
- Consumer Attitudes and Food Labeling
- Renal Transplantation Outcomes and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Pancreatic function and diabetes
- Pregnancy and preeclampsia studies
- Blood Pressure and Hypertension Studies
- Medicinal Plants and Neuroprotection
- Body Composition Measurement Techniques
Baylor College of Medicine
2015
The University of Texas Health Science Center at Houston
2015
Crystal Technology and Industries (United States)
2015
MB Clinical Research and Consulting (United States)
2009-2012
Glen Ellyn Public Library
2009-2011
Methodist Hospital
2010
University of Colorado Denver
2006
National Jewish Health
2006
RTI International
2006
This study evaluated the effects of 2 levels intake high-amylose maize type resistant starch (HAM-RS2) on insulin sensitivity (SI) in participants with waist circumference ≥89 (women) or ≥102 cm (men). Participants received 0 (control starch), 15, 30 g/d (double-blind) HAM-RS2 random order for 4-wk periods separated by 3-wk washouts. Minimal model SI was assessed at end each period using insulin-modified i.v. glucose tolerance test. The efficacy evaluable sample included 11 men and 22 women...
Restricted intakes of saturated and trans-fatty acids is emphasized in heart-healthy diets, replacement with poly- monounsaturated fatty encouraged.To compare the effects polyunsaturated acid-rich corn oil (CO) extra-virgin olive (EVOO) on plasma lipids men women (N = 54) fasting low-density lipoprotein cholesterol (LDL-C) ≥130 mg/dL <200 triglycerides (TG) ≤350 mg/dL.In a double-blind, randomized, crossover design (21-day treatments, 21-day washout between), 4 tablespoons/day CO or EVOO...
The objective of the present trial was to assess effects vitamin D supplementation on serum 25-hydroxyvitamin [25(OH)D] and high-density lipoprotein cholesterol (HDL-C) in subjects with high waist circumference. Subjects were randomly assigned a daily multivitamin mineral (MVM) supplement or MVM plus 1,200 IU/day (MVM+D) for 8 weeks. There significant difference mean change 25(OH)D between MVM+D treatment groups ( − 1.2 ± 2.5 nmol/l vs. 11.7 3.0 nmol/l, respectively; P = 0.003). Vitamin did...
This randomized, placebo-controlled, crossover trial assessed the lipid-altering efficacy of a softgel capsule dietary supplement, providing esterified plant sterols/stanols 1.8 g/d, in 28 participants (∼75% women) with primary hypercholesterolemia (fasting low-density lipoprotein cholesterol [LDL-C] levels ≥130 and <220 mg/dL), mean age 58.4 y, body mass index 27.9 kg/m2. After 5-wk National Cholesterol Education Program (NCEP) Therapeutic Lifestyle Changes (TLC) diet single-blinded placebo...
Dietary protein at breakfast has been shown to enhance satiety and reduce subsequent energy intake more so than carbohydrate or fat. However, relatively few studies have assessed substitution of for on indicators appetite glucose homeostasis simultaneously.The acute appetitive metabolic effects commercially-prepared sausage egg-based meals two different levels (30 g 39 g/serving), vs. a low-protein pancake (3 protein) no (water), were examined in premenopausal women (N = 35; age 32.5 ± 1.6...
Background: A liquid meal tolerance test (LMTT) has been proposed as a useful alternative to more labor-intensive methods of assessing insulin sensitivity and secretion. Objective: This substudy, conducted at the conclusion randomized, double-blind crossover trial, compared indices from LMTT (Matsuda index [MISI] disposition [LMTT-DI]) with derived minimal model analysis results insulin-modified intravenous glucose (IVGTT) (insulin [SI] [DI]). Results: Participants included men (n = 16)...
This randomized, placebo-controlled, crossover trial assessed the lipid-altering efficacy of a dietary supplement (tablet form) providing 1.8 g/day free (non-esterified) plant sterols and stanols versus placebo for 6 weeks as part therapeutic lifestyle changes (TLC) diet in 32 men women with primary hypercholesterolaemia. Mean ± SE baseline (end 5-week TLC lead-in) lipid concentrations (mmol/l) were total cholesterol (TC), 5.88 0.08; non-high-density lipoprotein (non-HDL-C), 4.71 0.09;...
This double-blind, randomized crossover study investigated the effects of 6 weeks treatment with prescription omega-3-acid ethyl esters (POM3, 4 g/day) versus placebo (soy oil) on low-density lipoprotein cholesterol (LDL-C) and other aspects fasting lipid profile in 31 men women primary, isolated hypercholesterolemia (LDL-C 130-220 mg/dL triglycerides less than 150 while free lipid-altering therapies). Mean ± standard error mean baseline concentrations total cholesterol, LDL-C, high-density...
Despite advances in surgery and pharmacotherapy, there remains significant residual ischemic risk after coronary artery bypass grafting surgery. In REDUCE-IT (Reduction of Cardiovascular Events With Icosapent Ethyl-Intervention Trial), a multicenter, placebo-controlled, double-blind trial, statin-treated patients with controlled low-density lipoprotein cholesterol mild to moderate hypertriglyceridemia were randomized 4 g daily icosapent ethyl or placebo. They experienced 25% reduction...
Effects of low-fat dairy intake on blood pressure, endothelial function, and lipoprotein lipids in subjects with prehypertension or stage 1 hypertension Kevin C Maki,1 Tia M Rains,1 Arianne L Schild,1 Mary R Dicklin,1 Keigan Park,2 Andrea Lawless,1 Kathleen Kelley1 1Biofortis Clinical Research, Addison, IL, USA; 2Dairy Research Institute/National Dairy Council, Rosemont, USA Objective: This randomized crossover trial assessed the effects 5 weeks consuming (one serving/day each 1% fluid milk,...
Several national and international health organizations have current recommendations for increasing dietary supplemental intakes of omega-3 fatty acids (eicosapentaenoic acid docosahexaenoic acid) the primary secondary prevention cardiovascular disease management hypertriglyceridemia. Clinical trials prescription as monotherapy or an adjunct to statin therapy supported its efficacy improving lipid profile (reducing triglycerides triglyceride-rich lipoproteins raising HDL-C) in individuals...
The role of omega-3 (OM3) fatty acids in the reduction elevated triglycerides is well recognized. This has prompted development concentrated OM3 drugs for treatment hypertriglyceridemia, a condition that may increase risk cardiovascular disease and pancreatitis. Intestinal absorption currently available ethyl ester depends on activity pancreatic lipases, largely stimulated by dietary fat. As many patients with severe hypertriglyceridemia are advised to minimize fat intake, there need product...