A5100442373- Animal Virus Infections Studies
- Aquaculture Nutrition and Growth
- Genetic diversity and population structure
- Neurological Disease Mechanisms and Treatments
- Viral gastroenteritis research and epidemiology
- Fermentation and Sensory Analysis
- GABA and Rice Research
- Protein Hydrolysis and Bioactive Peptides
- Pesticide Exposure and Toxicity
- Food Quality and Safety Studies
- Aluminum toxicity and tolerance in plants and animals
- Fish Biology and Ecology Studies
- Virus-based gene therapy research
- Fungal Biology and Applications
- Phytochemistry and Biological Activities
- Evolution and Genetic Dynamics
- Crustacean biology and ecology
- RNA Interference and Gene Delivery
- Neuroinflammation and Neurodegeneration Mechanisms
- Inflammatory Bowel Disease
- Barrier Structure and Function Studies
- Gut microbiota and health
- Agriculture, Soil, Plant Science
- Microbial Metabolism and Applications
- Identification and Quantification in Food
China Agricultural University
2011-2025
Nanjing Medical University
2007-2024
Capital Medical University
2007-2024
Sichuan University
2003-2024
Luoyang Institute of Science and Technology
2023-2024
Shandong University
2011-2024
Jiangnan University
2007-2024
Xinjiang Academy of Agricultural and Reclamation Science
2017-2024
Jiangxi Agricultural University
2015-2024
Wuhu No 1 People's Hospital
2024
Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing the viruses carried by pangolins is a logical approach to evaluate range potential pathogens help with conservation. This study provides insight into viral communities Malayan (Manis javanica) as well molecular epidemiology dominant pathogenic between Pangolin other hosts. A total 62,508 de novo assembled contigs were constructed, BLAST search revealed 3600 ones (≥300 nt) related sequences, which 68...
Microplastics (MPs) are environmental pollutants and can be inhaled by humans to threaten health. The lung tissue, responsible for the gas exchange between body environment, is vulnerable MPs exposure. However, from perspective of cellular senescence, effect on cells tissues has not yet been deeply dissected. In this study, we reported that all four typical exhibited significant biological effects in term inducing senescence human derived A549 BEAS-2B vitro. We further found polyvinyl...
During brain injury, extracellular adenosine and glutamate levels increase rapidly dramatically. We hypothesized that local in the dictates adenosine–adenosine A 2A receptor (A R) effects on neuroinflammation damage outcome. Here, we showed that, presence of low concentrations glutamate, R agonist 3-[4-[2-[[6-amino-9-[(2 ,3 ,4 S ,5 )-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]purin-2-yl]amino]ethyl]phenyl]propanoic acid (CGS21680) inhibited lipopolysaccharide (LPS)-induced nitric oxide...
Aging negatively affects B cell production, resulting in a decrease B-1 and B-2 cells impaired antibody responses. Age-related subsets contribute to inflammation. Investigating age-related alterations the B-cell pool developing targeted therapies are crucial for combating autoimmune diseases elderly. Additionally, optimal nutrition, including carbohydrates, amino acids, vitamins, especially lipids, play vital role supporting immune function mitigating decline activity. Research on influence...
The present study was undertaken to investigate the protective effect of H2S against myocardial ischemia-reperfusion (I/R) injury and its possible mechanism by using isolated heart perfusion patch clamp recordings. Rat hearts were Langendorff-perfused subjected a 30-minute ischemia insult followed reperfusion. function assessed measuring LVDP, +/-dP/dt max, arrhythmia score. results showed that treatment with donor (40 micromol/L NaHS) during reperfusion resulted in significant improvement...
Corn gluten meal (CGM) was hydrolyzed by Alcalase after starch removal of CGM applied as a pretreatment. A new inhibitory peptide for angiotensin I-converting enzyme (ACE) isolated from the hydrolysate with use Bio-Rad P-2 gel filtration and followed reverse-phase high-performance liquid chromatography (RP-HPLC). The sequence active determined to be Ala–Tyr application amino acid analysis HPLC/MS. IC50 14.2 µM, it not affected preincubation 30 mU ACE at 37 °C 3 h. also exerted...
The swimming crab Portunus trituberculatus is a commercially important species in East Asia countries. Gonadal development physiological process of great significance to the reproduction as well commercial seed production for P. trituberculatus. However, little currently known about molecular mechanisms governing developmental processes gonads this species. To open avenues research on gonadal development, Illumina paired-end sequencing technology was employed develop deep-coverage...
Prenatal exposure to organophosphorous (OP) pesticides has been found be associated with adverse effects on child neurodevelopment, but evidence potential induced by both prenatal and postnatal OP in infants is limited.Our aim was investigate the associations of birth outcomes infant neurodevelopment.Exposure 310 mother-infant pairs assessed measuring dimethylphosphate (DM), diethylphosphate (DE), total dialkylphosphate (DAP) metabolites urines from pregnant women their children at 2 years...
The trace element zinc is often used in the diet of weaned piglets, as high doses have resulted positive effects on intestinal health. However, majority previous studies evaluated supplementations for a short period only and focused small intestine. hypothesis present study was that low, medium levels dietary (57, 164 2,425 mg Zn/kg from oxide) would affect colonic morphology innate host defense mechanisms across 4 weeks post-weaning. Histological examinations were conducted regarding...
Cotton is widely cultivated globally because it provides natural fibre for the textile industry and human use. To identify quantitative trait loci (QTLs)/genes associated with quality yield, a recombinant inbred line (RIL) population was developed in upland cotton. A consensus map covering whole genome constructed three types of markers (8295 markers, 5197.17 centimorgans (cM)). Six yield traits were evaluated 17 environments, 983 QTLs identified, 198 which stable mainly distributed on...
Strains of Saccharomyces cerevisiae used to make beer, bread, and wine are genetically phenotypically distinct from wild populations associated with trees. The origins these domesticated not always clear; human-associated migration admixture have had a strong impact on S. population structure. We examined the genetic history beer strains found that ale portion allotetraploid lager were derived between closely related European grape Asian rice strains. Similar both baking strains, polyploid,...
Corn bran has been used as an ingredient for pigs, but the underlying mechanisms that improve gut health is less clear. This study was conducted to investigate effects of dietary corn on growth performance, nutrient digestibility, plasma indices related hormones and immunity, microbiota composition, fermentation products in weaned pigs. A total 60 pigs were allocated 2 treatments, piglets each group received control (CON) diet or 5% (CB) 28 d. Growth immunity evaluated. Microbiota...
Rheum rhabarbarum has been widely used as a herbal medicine and food in China. The objective of this study was to investigate the cytoprotective action underlying mechanisms rhein, one active ingredient isolated from R. rhabarbarum, on H2O2-challenged rat small intestine epithelial cells (IEC-6 cells). IEC-6 were incubated pretreatment with or without rhein LY294002, PI3K/Akt inhibitor. cell viability, apoptosis, intracellular reactive oxygen species (ROS), antioxidants measured. expressions...
Histological healing is closely associated with improved long-term clinical outcomes and lowered relapses in patients ulcerative colitis (UC). Here, we developed a novel diagnostic criterion for assessing histological UC patients.
Strawberry root rot caused by Fusarium solani is one of the main diseases strawberries and significantly impacts yield quality strawberry fruit. Biological control becoming an alternative method for plant to replace or decrease application traditional chemical fungicides. To obtain antagonistic bacteria with a high biocontrol effect on rot, over 72 rhizosphere were isolated from soil screened their antifungal activity against F. dual culture assay. Among them, strains CMS5 CMR12 showed...