A5040331037- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Mass Spectrometry Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Metabolomics and Mass Spectrometry Studies
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Advanced Chemical Sensor Technologies
- Mesoporous Materials and Catalysis
- Plant Molecular Biology Research
- Advanced Proteomics Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Electrochemical sensors and biosensors
- Pesticide Residue Analysis and Safety
- RNA and protein synthesis mechanisms
- Plant Stress Responses and Tolerance
- Cancer-related gene regulation
- Analytical Chemistry and Sensors
- Innovative Microfluidic and Catalytic Techniques Innovation
- Molecular Sensors and Ion Detection
- Pharmacological Effects and Assays
- Protein purification and stability
- Chemical Synthesis and Characterization
- Cancer-related molecular mechanisms research
- Amino Acid Enzymes and Metabolism
Wuhan University
2016-2025
Zhongnan Hospital of Wuhan University
2022-2025
Wuhan Textile University
2024-2025
Frontier Science Foundation
2025
Hohai University
2025
Shaanxi University of Science and Technology
2022-2025
Taiyuan University of Technology
2025
First Affiliated Hospital of Wannan Medical College
2025
Textron Systems (United Kingdom)
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2025
Gibberellin (GA), a diterpene hormone, plays diverse roles in plant growth and development, including seed germination, stem elongation, flowering time. Although it is known that GA accelerates through degradation of transcription repressors, DELLAs, the underlying mechanism poorly understood. We show here DELLA directly binds to microRNA156 (miR156)-targeted SQUAMOSA PROMOTER BINDING-LIKE (SPL) factors, which promote by activating miR172 MADS box genes. The interaction between SPL...
Seed dormancy is an important economic trait for agricultural production. Abscisic acid (ABA) and Gibberellins (GA) are the primary factors that regulate transition from to germination, they this process antagonistically. The detailed regulatory mechanism involving crosstalk between ABA GA, which underlies seed dormancy, requires further elucidation. Here, we report ABI4 positively regulates while negatively regulating cotyledon greening, by mediating biogenesis of GA. Seeds Arabidopsis abi4...
The phytohormone cytokinin (CK) positively regulates the activity and function of shoot apical meristem (SAM), which is a major parameter determining seed production. rice ( Oryza sativa L.) Gn1a / OsCKX2 Grain number 1a Cytokinin oxidase 2 ) gene, encodes oxidase, has been identified as quantitative trait locus contributing to grain improvement in breeding practice. However, molecular mechanism how expression regulated planta remains elusive. Here, we report that zinc finger transcription...
Abscisic acid (ABA) and cytokinin are key hormones controlling plant development. How ABA interplay to control the transition from a dry seed into young seedling remains elusive. Here we undertook gain-of-function genetic screen identify ABA-insensitive mutants during germination in Arabidopsis using an estradiol-inducible approach. In presence of estradiol, one these gim1 (germination insensitive mutant 1) exhibited elevated level that was attributed estradiol-induced expression AtIPT8...
Brown planthopper (BPH), Nilaparvata lugens Stål, is one of the most devastating insect pests rice (Oryza sativa L.). Currently, 30 BPH-resistance genes have been genetically defined, which are clustered on specific chromosome regions. Here, we describe molecular cloning and characterization a gene, BPH9, mapped long arm 12 (12L). BPH9 encodes rare type nucleotide-binding leucine-rich repeat (NLR)-containing protein that localizes to endomembrane system causes cell death phenotype. activates...
Representing a basal branch of arachnids, scorpions are known as 'living fossils' that maintain an ancient anatomy and adapted to have survived extreme climate changes. Here we report the genome sequence Mesobuthus martensii, containing 32,016 protein-coding genes, most among sequenced arthropods. Although M. martensii appears evolve conservatively, it has greater gene family turnover than insects undergone diverse morphological physiological changes, suggesting decoupling molecular...
Crown roots constitute the majority of rice (Oryza sativa) root system and play an important role in growth development. However, molecular mechanism crown formation is not well understood. Here, we characterized a dominant mutant, enhancer1 (ren1-D), which was observed to exhibit more robust system, increased number, reduced plant height. Molecular genetic analyses revealed that these phenotypes are caused by activation cytokinin oxidase/dehydrogenase (CKX) family gene, OsCKX4. Subcellular...
The epithelial mucosa is a key biological barrier faced by gastrointestinal, intraoral, intranasal, ocular, and vaginal drug delivery. Ligand-modified nanoparticles demonstrate excellent ability on this process, but their efficacy diminished the formation of protein coronas (PCs) when they interact with matrices. PCs are broadly implicated in affecting fate NPs vivo vitro, yet few studies have investigated formed during interactions mucosa, especially mucus. In study, we constructed...
Abstract Plant height is a decisive factor in plant architecture. Rice (Oryza sativa) plants have the potential for rapid internodal elongation, which determines height. A large body of physiological research has shown that ethylene and gibberellin are involved this process. The APETALA2 (AP2)/Ethylene-Responsive Element Binding Factor (ERF) family transcriptional factors only present kingdom. This various developmental functions. rice AP2/ERF gene, OsEATB (for ERF protein associated with...
N(6)-methyladenosine (m(6)A) modification plays a fundamental role in the epigenetic regulation of mammalian transcriptome. m(6)A can be demethylated by fat mass- and obesity-associated (FTO) protein α-ketoglutarate-dependent dioxygenase alkB homolog 5 (ALKBH5) protein. However, importance alteration type 2 diabetes mellitus (T2DM) has not been explored.The objective study was to investigate whether content reduced T2DM patients correlated with mRNA expression levels FTO ALKBH5 genes.In this...
Abstract The kinesins are a family of microtubule-based motor proteins that move directionally along microtubules and involved in many crucial cellular processes, including cell elongation plants. Less is known about directly regulating gene transcription to affect physiological processes. Here, we describe rice (Oryza sativa) mutant, gibberellin -deficient dwarf1 (gdd1), has phenotype greatly reduced length root, stems, spikes, seeds. This due decreased can be rescued by exogenous...
A novel boronate affinity monolith, poly(3-acrylamidophenylboronic acid-co-ethylene dimethacrylate) (AAPBA-co-EDMA), was prepared in 530 µm capillaries by a one-step situpolymerization procedure using pre-polymerization mixture consisting of functional monomer 3-acrylamidophenylboronic acid, cross-linker ethylene dimethacrylate, porogenic solvent methanol with added poly(ethylene glycol) 20 000 (PEG 000) and initiator azobisisobutyronitrile (AIBN). The preparation the monolith optimized...
Abstract In this work, a novel method for the fabrication of magnetic carbon nanotubes based on ‘aggregation wrap’ was proposed. When and nanoparticles were vortically mixed in solvent, wrapped into nanotube bundles that formed during aggregation process, leading to formation nanotubes. Thus, resultant material can be separated from solvent rapidly conveniently by magnet. Our investigation demonstrated mechanism preparation composite is also applicable other self‐aggregated...
In this study, a nanocomposite of polypyrrole-coated magnetite nanoparticles (denoted as MNPs/PPy) was prepared and employed magnetic solid-phase extraction (MSPE) sorbent for estrogens from milk samples. Because the polypyrrole coating possessed highly π-conjugated structure hydrophobicity, MNPs/PPy showed excellent performance estrogen extraction. Estrogens could be captured directly by samples without protein precipitation. Moreover, carried out within 3 min. Thus, rapid, simple,...
Soybean is an important and staple oilseed crop worldwide. Salinity stress has adverse effects on soybean development periods, especially seed germination post-germinative growth. Improving emergence will have positive under salt conditions agricultural production. Here we report that NaCl delays by negatively regulating gibberellin (GA) while positively mediating abscisic acid (ABA) biogenesis, which leads to a decrease in the GA/ABA ratio. This study suggest fluridone (FLUN), ABA...