A5019827467- Breast Implant and Reconstruction
- Reconstructive Surgery and Microvascular Techniques
- Clostridium difficile and Clostridium perfringens research
- Body Image and Dysmorphia Studies
- Gastrointestinal motility and disorders
- Social Media in Health Education
- Focus Groups and Qualitative Methods
- Health Literacy and Information Accessibility
- Breast Cancer Treatment Studies
- Gut microbiota and health
- Impact of Technology on Adolescents
- Consumer Behavior in Brand Consumption and Identification
- Olfactory and Sensory Function Studies
- Ubiquitin and proteasome pathways
- Obstructive Sleep Apnea Research
- Glycosylation and Glycoproteins Research
- T-cell and B-cell Immunology
- Nasal Surgery and Airway Studies
- Cleft Lip and Palate Research
- Mental Health via Writing
- Protein Tyrosine Phosphatases
- Immune Cell Function and Interaction
- Sphingolipid Metabolism and Signaling
University of Pennsylvania Health System
2024
University of Kansas Medical Center
2020-2022
Creative Commons
2020
University of Kansas
2020
Kansas State University
2011-2016
University of California, San Francisco
2014
Clostridium difficile produces an NAD-specific glutamate dehydrogenase (GDH), which converts l-glutamate into α-ketoglutarate through irreversible reaction. The enzyme GDH is detected in the stool samples of patients with C. difficile-associated disease and serves as one diagnostic tools to detect infection (CDI). We demonstrate here that supernatant fluids cultures contain GDH. To understand role physiology difficile, isogenic insertional mutant gluD was created strain JIR8094. failed...
Clostridium difficile is the principal cause of antibiotic-associated diarrhea. Major metabolic requirements for colonization and expansion C. after microbiota disturbance have not been fully determined. In this study, we show that glutamate utilization important to establish itself in animal gut. When gluD gene, which codes dehydrogenase (GDH), was disrupted, mutant unable colonize disease a hamster model. Further, from complementation experiment it appears extracellular GDH may be playing...
Plastic surgeons and patients increasingly use social media. Despite evidence implicating its importance in plastic surgery, the large volume of data has made media difficult to study.The aim this study was provide a comprehensive assessment surgery content worldwide by utilizing techniques for analyzing large-scale data.The hashtag "#PlasticSurgery" used search public Instagram posts. Metadata were collected from posts between December 2018 August 2020. In addition descriptive analysis, 2...
Background Analysis of chromosomal rearrangements within primary tumors has been influential in the identification novel oncogenes. Identification "driver" gene(s) cancer-derived amplicons is, however, hampered by fact that most contain many gene products. Amplification 1q21–1q23 is strongly associated with liposarcomas and microarray-based comparative genomic hybridization narrowed down likely candidate oncogenes to two: activating transcription factor 6 (atf6) dual specificity phosphatase...
Importance Necrosis of the nipple-areolar complex (NAC) is Achilles heel nipple-sparing mastectomy (NSM), and it can be difficult to assess which patients are at risk this complication ( Ann Surg Oncol 2014;21(1):100–106). Objective To develop validate a model that accurately predicts NAC necrosis in prospective cohort. Design Data were collected from retrospectively reviewed cohort who underwent NSM immediate breast reconstruction between January 2015 July 2019 our institution, high...
Management of cleft lip and palate has been well characterized in pediatric patients, but limited data exist regarding the long-term functional outcomes patients once they reach adulthood.An institutional, cross-sectional survey adult with a history and/or was performed. The recorded patient characteristics, concerns, barriers to care. Patient-reported outcome measures were assessed using Nasal Obstruction Symptom Evaluation Scale, Epworth Sleepiness Mandibular Function Impairment...
Abstract Background Instagram (Menlo Park, CA) is a major platform for the dissemination of plastic surgery (PS) information, but training background users difficult to ascertain. Objectives We sought better characterize source and content PS-related posts on Instagram. Methods Metadata from publicly available containing PS relevant hashtags was collected December 2018 August 2020 using Node.js (Node.js Foundation, San Francisco, CA). The data characterized by account type, post topics were...
PURPOSE: Despite the ubiquitous presence of plastic surgery content on Instagram, data have remained limited to individual time points from posts within United States.1,2 Here, we aim provide a comprehensive analysis Instagram users and pertaining globally. METHODS: Metadata publicly available containing #PlasticSurgery were collected December 2018 through January 2020 an API with Node.JS, open source JavaScript runtime environment. All timestamped timeframe included. Data included username,...
BACKGROUND & OBJECTIVES: Necrosis of the nipple-areolar complex (NAC) is Achilles' heel Nipple Sparing Mastectomy (NSM).1 Our goal was to create a user-friendly, validated technology platform that surgeons could utilize preoperatively predict which patients are at risk NAC necrosis and aid in shared decision-making. This prediction would be based on patient characteristics intraoperative variables. METHODS: We conducted retrospective review all NSM with immediate reconstruction performed our...