A5045776153- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Cancer Treatment and Pharmacology
- Breast Implant and Reconstruction
- Advanced Breast Cancer Therapies
- Global Cancer Incidence and Screening
- HER2/EGFR in Cancer Research
- Cancer Genomics and Diagnostics
- Reconstructive Surgery and Microvascular Techniques
- Cancer Cells and Metastasis
- Body Image and Dysmorphia Studies
- Diversity and Career in Medicine
- Lymphatic System and Diseases
- MRI in cancer diagnosis
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer and Skin Lesions
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Surgical Simulation and Training
- Advances in Oncology and Radiotherapy
- Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Vascular Tumors and Angiosarcomas
- Digital Imaging in Medicine
The University of Kansas Cancer Center
2018-2025
University of Kansas
2017-2024
University of Kansas Medical Center
2018-2024
Cleveland Clinic
2013-2018
Case Western Reserve University
2011-2014
University Hospitals Cleveland Medical Center
2011-2014
MetroHealth Medical Center
2014
MetroHealth
2014
Plastic Surgery Hospital
2014
The University of Texas Southwestern Medical Center
2011-2013
Addition of pembrolizumab to anthracycline-based chemotherapy improves pathologic complete response (pCR) and event-free survival (EFS) in triple-negative breast cancer (TNBC). The efficacy anthracycline-free chemoimmunotherapy TNBC has not been assessed.
Abstract Purpose: Addition of carboplatin (Cb) to anthracycline chemotherapy improves pathologic complete response (pCR), and plus taxane regimens also yield encouraging pCR rates in triple-negative breast cancer (TNBC). Aim the NeoSTOP multisite randomized phase II trial was assess efficacy anthracycline-free anthracycline-containing neoadjuvant regimens. Patients Methods: aged ≥18 years with stage I–III TNBC were (1:1) receive either paclitaxel (P) weekly × 12 AUC6 every 21 days 4 followed...
513 Background: Addition of pembrolizumab to anthracycline-taxane-platinum chemotherapy improves pathologic complete response (pCR) and event free survival (EFS) in TNBC. Aim this study was assess the efficacy anthracycline neoadjuvant regimen plus carboplatin docetaxel (Cb+D) Methods: In multicenter study, eligible patients with stage I-III TNBC received (AUC 6) + (75 mg/m 2 ) (200 mg) every 21 days x 6 cycles. The primary endpoint pCR (no evidence invasive tumor breast axilla). Secondary...
Neoadjuvant chemotherapy (NAC) increases rates of successful breast conserving surgery (BCS) in patients with cancer. However, some studies suggest that BCS after NAC may confer increased risk locoregional recurrence (LRR). We assessed LRR and free survival (LRFS) enrolled on I-SPY2 (NCT01042379), a prospective trial for clinical stage II-III, molecularly high-risk Cox proportional hazards models were used to evaluate associations between surgical procedure (BCS vs. mastectomy) LRFS adjusted...
The purpose of this study was to identify factors that contribute migraine headache surgery failure and success.A retrospective chart review conducted patients who underwent for headaches performed by the senior author (B.G.) had at least 11 months follow-up. population included three groups: success, improvement, failure. Thirty-six unique data points were collected each patient.A total 169 met inclusion criteria. Of these, 66 comprised success group (S, complete elimination headaches); 67...
Background: Individuals younger than 18 years represent an increasing number of cosmetic surgery patients. The goals this article are to address the unique psychological aspects teens and surgery; understand literature related adolescents consider methods for evaluating who present surgery, specifically focusing on nasal breast procedures. Methods: A PubMed search was performed using combinations keywords "cosmetic surgery," "adolescent," "psychology," "rhinoplasty," "breast...
Due to widespread adoption of screening mammography, there has been a significant increase in new diagnoses ductal carcinoma situ (DCIS). However, DCIS prognosis remains unclear. To address this gap, we developed an vivo model, Mouse-INtraDuctal (MIND), which patient-derived epithelial cells are injected intraductally and allowed progress naturally mice. Similar human DCIS, the cancer formed lesions inside mouse mammary ducts mimicked all histologic subtypes including micropapillary,...
Background: Cauterization, nasal packing, and topical and/or injection of intranasal vasoconstrictors have been the mainstay treatment for epistaxis following outpatient surgery. In this study, authors report clinical outcomes in a cohort patients with postoperative managed single dose intravenous desmopressin. Methods: A retrospective chart review 268 consecutive operations (rhinoplasty, septoplasty, turbinectomy cosmetic functional purposes) was conducted. Information on demographics,...
TPS629 Background: Neoadjuvant chemoimmunotherapy is recommended for patients with high risk early stage TNBC. The 5 drug KEYNOTE-522 neoadjuvant regimen involves 5-6 months of treatment and associated suboptimal completion due to toxicity. Approaches deescalate without compromising outcomes highly chemosensitive disease are needed. Stromal tumor infiltrating lymphocyte (sTIL) enrichment positively pathologic complete response (pCR) in TNBC may be useful identify whom de-escalation might...
Importance Active monitoring (AM) for low-risk ductal carcinoma in situ (DCIS) has been considered as a potential alternative to guideline-concordant care (GCC; inclusive of surgery with or without radiation). Reported data comparing patient-reported outcomes (PROs) between GCC and AM DCIS are lacking. Objective To compare PROs at baseline over time patients randomized receive either GCC. Design, Setting, Participants This prespecified secondary outcome analysis used prospectively collected...
Milk fistula is an uncommon condition which occurs when there abnormal connection that forms between the skin surface and duct in breast of a lactating woman, resulting spontaneous often constant drainage milk from this path least resistance. A usually complication results needle biopsy or surgical intervention patient. Here, authors present unusual case developed abscess woman. The patient initially presented to office with large open wound on her breast, formed breakdown, within was...
Background: This study examines the potential contributions of environmental factors to variations in facial symmetry between identical twins. Methods: Identical male and female twins were recruited from Twins Days Festival 2009 2010. Subjects independently completed a comprehensive questionnaire on their medical personal history, then posed for digital photography several different angles. Eight features these photographs measured using Adobe Photoshop, analyzed against survey responses...
Background: In the last several years, federal funding has become increasingly difficult to obtain. The purpose of this project was define level among plastic surgeons in modern era. Methods: authors evaluated members Plastic Surgery Research Council because their expected invested interested research. collected information from 1998 2012 on using curricula vitae and publically available online tools. Data Foundation also determine its role supporting federally funded investigators. Results:...
Background: The anatomy curriculum has undergone considerable reductions in class time, resulting decreased student anatomical knowledge retention and confidence during their surgical rotations. To counter this deficit knowledge, a clinical mentorship program (CAMP) was developed by fourth-year medical leaders staff mentors near-peer teaching fashion prior to the clerkship. This study analyzed impact had on third-year students (MS3s) self-assessed operating room Breast Surgical Oncology...
Background: The goal of this study was to evaluate the relationship between body mass index, preoperative weight loss, and patient satisfaction in breast reconstruction with abdominally based free flaps. Methods: A custom survey overall, breast, abdomen questions sent patients who underwent flap over past 4 years. Clinical data were collected for returned surveys. Data analysis performed on index percentage loss before surgery. Results: One hundred seventy-nine surveys sent. Ninety-two (51.4...
Background: Frontal bossing is a displeasing prominence of the supraorbital area. Aesthetic correction has been described as an open surgical technique. This report introduces endoscopic approach to correction. Methods: A retrospective review was performed on all patients who underwent repair frontal from 2002 2009. Demographics, intraoperative and postoperative course, outcome variables were collected. Standardized preoperative photographs used for analysis. improvement forehead assessed...