A5029748536- Breast Cancer Treatment Studies
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Photoacoustic and Ultrasonic Imaging
- Sarcoma Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Optical Imaging and Spectroscopy Techniques
- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Vascular Tumors and Angiosarcomas
- Reconstructive Surgery and Microvascular Techniques
- Radiomics and Machine Learning in Medical Imaging
- BRCA gene mutations in cancer
- Gold and Silver Nanoparticles Synthesis and Applications
- Lymphatic System and Diseases
- Cardiac tumors and thrombi
- Nanoparticle-Based Drug Delivery
- Gastric Cancer Management and Outcomes
- Cancer and Skin Lesions
- AI in cancer detection
- Cancer Genomics and Diagnostics
- Cutaneous Melanoma Detection and Management
- Economic and Financial Impacts of Cancer
- MRI in cancer diagnosis
- Pancreatitis Pathology and Treatment
Abu Dhabi Health Services
2024
Cleveland Clinic
2013-2022
Hochschule Düsseldorf University of Applied Sciences
2020-2021
Case Western Reserve University
2015-2021
Délégation Paris 6
2019-2021
Cleveland Clinic Lerner College of Medicine
2015-2021
IVI Middle East Fertility Clinic
2021
Wolfram Research (United States)
2020
Cleveland Foundation
2020
Los Angeles City College
2020
Delays in time to treatment initiation (TTI) for new cancer diagnoses cause patient distress and may adversely affect outcomes. We investigated trends TTI common solid tumors treated with curative intent, determinants of increased association overall survival.We utilized prospective data from the National Cancer Database newly diagnosed United States patients early-stage breast, prostate, lung, colorectal, renal pancreas cancers 2004-13. was defined as days diagnosis first (surgery, systemic...
Currently, over half of breast cancer cases are unrelated to known risk factors, highlighting the importance discovering other cancer-promoting factors. Since crosstalk between gut microbes and host immunity contributes many diseases, we hypothesized that similar interactions could occur recently described microbiome local immune responses influence pathogenesis.
Purpose To compare the diagnostic utility of an investigational optoacoustic imaging device that fuses laser optical (OA) with grayscale ultrasonography (US) to US alone in differentiating benign and malignant breast masses. Materials Methods This prospective, 16-site study 2105 women (study period: 12/21/2012 9/9/2015) compared Breast Imaging Reporting Data System (BI-RADS) categories assigned by seven blinded independent readers masses using OA/US versus alone. BI-RADS 3, 4, or 5 assessed...
Photoacoustic tomography (PAT) is a rapidly emerging non-invasive imaging technology that integrates the merits of high optical contrast with ultrasound resolution. The ability to quantitatively and non-invasively image nanoparticles has important implications for development as in vivo cancer diagnostic therapeutic agents. In this study, systemically administered poly(ethylene glycol)-coated (PEGylated) gold agent tumor PAT been evaluated. We demonstrate (20 50 nm) have photoacoustic...
To determine if ifosfamide-based chemotherapy (IF) offers a survival benefit to adult patients with primary extremity synovial sarcoma.
// Hannah Wang 1, 2 , Jessica Altemus 1 Farshad Niazi Holly Green 4 Benjamin C. Calhoun 5 Charles Sturgis Stephen R. Grobmyer 2, 4, 6, 8 and Charis Eng 3, 7, Genomic Medicine Institute, Lerner Research Cleveland Clinic, Cleveland, OH, USA Clinic College of Medicine, 3 Taussig Cancer Surgical Oncology, Digestive Disease Surgery Department Anatomic Pathology, Robert J. Tomsich Pathology Laboratory 6 Comprehensive Breast Program, 7 Genetics Genome Sciences, Case Western Reserve University...
To determine the utility of MRI for assessing axillary lymph node status in patients with breast cancer.A consecutive series who underwent MR before surgical management cancer sampling between 2005 and 2007 were identified. MRs evaluated number nodes, contrast kinetics, nodal area, nodes no fatty hilum. Data analyzed context final pathology, sentinel status, status. Correlations using Kendall's tau-b test. Reported P values are one-sided.Fifty-six females (median = 58 years) studied....
To assess the value of preoperative imaging studies and intraoperative assessment perihepatic lymph nodes in patients undergoing partial hepatectomy for malignancy.Perihepatic node status is an important prognostic factor hepatic resection 1(o) metastatic cancer. The unknown.Perihepatic were sampled 100 malignancy. At time sampling, participating surgeons assigned a clinical suspicion score (scale, 1-5: 1 = clinically negative, 5 positive). Preoperative CT scans PET reviewed blinded fashion...
Esophageal cancer in the United States carries a poor prognosis with overall 5 year survival rate of approximately 10%. Due to this dismal outcome, data analyzing factors predictive for greater than years are not available.Single institution retrospective review esophageal resection curative intent from 1984 2004. We identified 50 actual survivors (long term survivors, LTS) out 266 patients (19%) invasive and, using multivariate logistic regression, compared characteristics between LTS, and...
The novel optical properties of polyhydroxy fullerenes (PHF)—which are water-soluble, biodegradable and antioxidant—are applied for imaging therapy cancer. Tumors injected with PHF imaged photoacoustic tomography (PAT) photothermally treated near-infrared (NIR) laser. Tumor size decreases up to 72% within two hours treatment, only a blister visible after 20 hours. Detailed facts importance specialist readers published as "Supporting Information". Such documents peer-reviewed, but not...
The use of photoacoustic effect is a promising approach for biomedical imaging in living tissues. Photoacoustic tomography (PAT) has been demonstrated to image breast cancer, brain vasculature, arthritis and seizure focus owing its rich optical contrast high resolution single modality. Here we report microelectromechanical systems (MEMS)-based intraoperative PAT (iPAT) technique, demonstrate ability accurately map tumors three-dimension inspect the completeness tumor resection during surgery...
Purpose : The authors present the design and evaluation of a second‐generation (G2) hybrid photoacoustic tomography (PAT) diffuse optical (DOT) imaging system for detection breast cancer. combined PAT/DOT takes full advantages two different modalities to provide complementary information most accurate recovery tissue properties. Methods This was designed produce cross‐section images with ring‐shaped home‐made array 64 wideband acoustic transducers an 16/16 source/detector fiber bundles. A...
Abstract Purpose: To develop targeted molecular imaging probes for the noninvasive detection of breast cancer lymph node metastasis. Experimental Design: Six cell surface or secreted markers were identified by expression profiling and from literature as being highly expressed in metastases. Two these carbonic anhydrase isozymes (CAIX and/or CAXII) validated protein immunohistochemistry patient tissue samples on a microarray containing 47 normal samples, 42 ductal carcinoma situ, 43 invasive...
Cancer is one of the leading causes death throughout world. Advancements in early and improved diagnosis could help prevent a significant number these deaths. Raman spectroscopy vibrational spectroscopic technique which has received considerable attention recently with regards to applications clinical oncology. potential not only improve cancer but also advance treatment cancer. A studies have investigated for its wide variety cancers. In this paper most recent advances dispersive...