Christopher M. Lock

ORCID: 0000-0002-5684-753X
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About
Contact & Profiles
Research Areas
  • Mass Spectrometry Techniques and Applications
  • Ion-surface interactions and analysis
  • Pesticide Residue Analysis and Safety
  • Analytical chemistry methods development
  • Spectroscopy and Chemometric Analyses
  • Meat and Animal Product Quality
  • Advanced Chemical Sensor Technologies
  • NMR spectroscopy and applications
  • Salmonella and Campylobacter epidemiology
  • Analytical Chemistry and Sensors
  • Sensory Analysis and Statistical Methods
  • Mercury impact and mitigation studies
  • Fullerene Chemistry and Applications
  • Isotope Analysis in Ecology
  • Metabolomics and Mass Spectrometry Studies
  • Scientific Research and Discoveries
  • Genomics and Phylogenetic Studies
  • Computational Physics and Python Applications
  • Advanced Chemical Physics Studies
  • Bacteriophages and microbial interactions
  • Atomic and Molecular Physics
  • Mechanical and Optical Resonators
  • X-ray Spectroscopy and Fluorescence Analysis
  • Electrochemical Analysis and Applications
  • Identification and Quantification in Food

United States Food and Drug Administration
2019-2023

Pacific Northwest National Laboratory
2021

Institute for Marine Biosciences
1998

University of Wales
1995-1997

Swansea University
1995-1997

Abstract The sequencing, assembly, and analysis of bacterial genomes is central to tracking characterizing foodborne pathogens. bulk genome sequencing at the US Food Drug Administration performed using short-read Illumina MiSeq technology, resulting in highly accurate but fragmented genomic sequences. MinION sequencer from Oxford Nanopore an evolving technology that produces long-read data with low equipment cost. goal this study was compare Campylobacter assemblies generated independently,...

10.1038/s41598-021-84956-6 article EN cc-by Scientific Reports 2021-03-11

The effect on triple-quadrupole performance of applying an axial field, in rf-only quadrupole collision cell operated at pressures sufficiently high that collisional focusing is operating, has been investigated. advantages such cells have shown previously to include increased transmission and much improved resolution fragment ion spectra relative the operating lower gas pressures. disadvantages high-pressure all derive from relatively long transit times for ions, which can be characteristic...

10.1016/s1044-0305(98)00042-7 article EN Journal of the American Society for Mass Spectrometry 1998-08-01

Nontarget data acquisition for target analysis (nDATA) workflows using liquid chromatography-high-resolution accurate mass (LC-HRAM) spectrometry, spectral screening software, and a compound database have generated interest because of their potential pesticides in foods. However, these procedures particularly the instrument processing software need to be thoroughly evaluated before implementation routine analysis. In this work, 25 laboratories participated collaborative study evaluate an...

10.1021/acs.jafc.1c04437 article EN Journal of Agricultural and Food Chemistry 2021-10-28

Abstract Sensory analysis is performed in USFDA testing laboratories to determine the decomposition status of seafood samples. Current alternatives are not always directly comparable sensory testing. In this study, a novel method was explored using LC‐HRMS with untargeted and statistical model driven by results via script written R programming language. This allows generation data, which commonly used scoring techniques. The applied six species salmon, across wide range conditions. Accuracy...

10.1111/jfs.12676 article EN Journal of Food Safety 2019-06-25

Abstract Samples of 23 seafood products were obtained internationally in processing plants and subjected to controlled decomposition produce seven discrete quality increments. A sensory expert evaluated each sample for decomposition, using a scale 1–100. then extracted analyzed by liquid chromatography with high‐resolution mass spectrometry (LC‐HRMS). Untargeted data was performed, sensory‐driven Random Forest model the R programming language product created. Five samples increment duplicate...

10.1002/fsn3.2223 article EN Food Science & Nutrition 2021-03-11

10.1002/(sici)1097-0231(199707)11:11<1155::aid-rcm957>3.0.co;2-e article EN Rapid Communications in Mass Spectrometry 1997-07-01

Seeking alternatives to sensory which can be performed in non-laboratory field environments has been a recent emphasis regulatory assessment of seafood decomposition. To this end, an international sampling effort produced samples 23 different products, were subjected controlled decomposition varying levels on ice. This each product for wide range states, and these scored by expert standard 1-100 scale. Samples then analyzed novel technique involving headspace analysis compact mass...

10.21423/jrs-v10a233 article EN cc-by-nc Journal of Regulatory Science 2023-01-19

Abstract A rapid and simple method for deconvolution of partially resolved spectra has been developed. The algorithm is simple, extremely fast, capable deconvolving whole in real time on a fast personal computer. technique evaluated using known test whose resolution purposely degraded. original were reproduced accurately, both the positions intensities individual peaks they contained. was initially developed translational energy spectroscopy (TES), where there little priori information...

10.1002/rcm.1290090208 article EN Rapid Communications in Mass Spectrometry 1995-01-01

Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation B. J. Starkey, C. M. Lock; Short Range Propagation of Mechanical Disturbances in the Ground. Appl. Phys. 1 June 1954; 25 (6): 816–817. https://doi.org/10.1063/1.1721748 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Dropdown Menu...

10.1063/1.1721748 article EN Journal of Applied Physics 1954-06-01
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