A5079548329- Autophagy in Disease and Therapy
- Tea Polyphenols and Effects
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Chemical Sensor Technologies
- Endoplasmic Reticulum Stress and Disease
- Food composition and properties
- Silymarin and Mushroom Poisoning
- MicroRNA in disease regulation
- Plant-based Medicinal Research
- Food Quality and Safety Studies
- Pancreatic function and diabetes
- Cardiovascular Function and Risk Factors
- Antimicrobial Peptides and Activities
- Proteins in Food Systems
- Electrospun Nanofibers in Biomedical Applications
- Phytochemicals and Antioxidant Activities
- Advanced biosensing and bioanalysis techniques
- Identification and Quantification in Food
- Circular RNAs in diseases
- Bee Products Chemical Analysis
- Drug Transport and Resistance Mechanisms
- Acute Ischemic Stroke Management
- Microencapsulation and Drying Processes
- Stroke Rehabilitation and Recovery
- Adipose Tissue and Metabolism
Shenyang Medical College
2025
Second Affiliated Hospital of Xi'an Jiaotong University
2016-2024
Chinese Center For Disease Control and Prevention
2024
National Institute for Occupational Health and Poison Control
2021-2024
Nantong University
2024
Affiliated Hospital of Nantong University
2024
Hubei University of Medicine
2020-2023
Taihe Hospital
2020-2023
Tsinghua–Berkeley Shenzhen Institute
2023
Tsinghua University
2023
Acute liver failure, rhabdomyolysis, acute renal and hemolysis caused by poisonous mushrooms are the most important mushroom poisoning threats to Chinese population. The notorious lethal species from genera
Mushroom poisoning is one of the most serious food safety issues in China. By end 2021, over 520 poisonous mushrooms had been discovered The Southwest region China was severely affected. poisonings mainly concentrated summer and autumn months.In 2022, CDC conducted an investigation 482 incidents mushroom across 21 provincial-level administrative divisions (PLADs). This resulted 1,332 patients 28 deaths, with a total case fatality rate 2.1%. A 98 were identified, causing 7 different clinical...
Mushroom poisoning poses a significant food safety concern in China, with total of 196 species identified incidents by the end 2022.
High lipid levels may constitute a more important risk factor for cognitive health in previous studies. However, the association of plasma lipids with mild impairment (MCI) among elderly people had not been studied exactly. This study aims to explore relationship between lipids/lipoproteins and MCI Chinese individuals.CSI-MCI was preliminary case-control 112 cases 115 cognitively normal controls. Plasma total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C),...
Patulin (PAT) is a common toxin in fruit juice, and adsorption the most commonly used patulin removal method. The safety, capacity, separation capacity of adsorbent are important considerations. As low-cost biocompatible microbial material, bacterial cellulose gel membranes (BCMs) have many hydroxyl active sites that readily modified, BCMs also stable, which facilitates their from aqueous solution. Therefore, promising material for adsorbing patulin. Through silanization, –SH was...
Objective This study aimed to develop and validate a nomogram for predicting the risk of 3 months adverse outcomes among young adults with acute ischemic stroke (AIS). Methods Patients aged between 18 50 (AIS) at Shenyang First’s People Hospital, January 1st 2017 May 30th 2023 were included in this retrospective study. The primary outcome was three-month unfavorable outcome, evaluated modified Rankin Scale (mRS > 2). Univariate logistic regression used select independent factors...
Abstract Background: Stroke, a leading cause of global disability, where timely thrombolysis is crucial for favorable outcomes. Despite initiatives like Acute Stroke Care Maps in China aiming to improve care continuity and rates, the long-term effectiveness these interventions urban settings remains underexplored. Methods: This retrospective cohort study investigates role Shenyang Map (ASCaM) improving rate with tissue plasminogen activator (tPA) within 4.5 hours ischemic stroke onset 30...
Continuous monitoring of the blood glucose levels is necessary for its diagnosis and treatment. In recent years, researchers have discovered a correlation between sweat glucose. The methodology obtaining value by detecting in expected to replace conventional diabetes detection. Flexible biosensor owns characteristics stretchability, comfortability, capability non-invasive promising candidate monitoring. this review, we summarize latest developments research applications flexible biosensors...
Background Autophagy plays important roles in cancer progression and therapeutic resistance, the autophagy underlying tumor pathogenesis further mechanisms of chemoresistance emergence remains unknown. Methods In this study, via single-sample gene set enrichment analysis (ssGSEA) method, an 45-gene list was identified to evaluate samples’ activity, verified through six GEO datasets with a confirmed phenotype. It utilized distinguish tumors into score-high score-low subtypes, analyze their...
Cardiac fibrosis is a major pathological manifestation of diabetic cardiomyopathy, which leading cause mortality in patients with diabetes. MicroRNA (miR)‑155 upregulated cardiomyocytes cardiac fibrosis, and the aim present study was to investigate if inhibition miR‑155 able ameliorate by targeting nuclear factor erythroid‑2‑related 2 (Nrf2)/heme oxygenase‑1 (HO‑1) signaling pathway. H9C2 rat were cultured high glucose (HG; 30 mM) establish an vitro model that mimicked conditions; inhibitor...
The effects of ultrasound treatment prior to the vacuum package and modified atmosphere on physical, microbial sensory characteristics beef meat stored at refrigerator 4ºC. Sampling was carried out 0, 3<SUP>rd</SUP>, 6<SUP>th</SUP>, 10<SUP>th</SUP>, 14<SUP>th</SUP>, 18<SUP>th</SUP> 22<SUP>th </SUP>day storage. initial bacteria loading slight same all samples load increase over time. extension shelf life may be due synergistic effect integration two types preservation used microbiological...
Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with an increased risk of death, but its underlying mechanisms are not fully understood. Circular RNAs (circRNAs) have recently been implicated in various biological processes. The aim this study was to investigate the key circRNAs related RA.A microarray assay used identify differentially expressed (DEcircRNAs) peripheral blood mononuclear cells (PBMCs) from patients RA compared osteoarthritis (OA) and healthy controls....
Diabetic cardiomyopathy (DC) is one of serious complications diabetic patients. This study investigated the biological function activating transcription factor 4 (ATF4) in DC.Streptozotocin-treated mice and high glucose (HG)-exposed HL-1 cells were used as vivo vitro models DC. Myocardial infarction (MI) was induced by left coronary artery ligation mice. Cardiac functional parameters detected echocardiography. Target molecule expression determined real time quantitative PCR western blotting....
This study aimed to explore the antibiofilm activity and possible mechanism of lactobionic acid (LBA) against Salmonella enterica subsp. serovar Typhimurium (S. Typhimurium). The minimum inhibitory concentration (MIC) LBA S. was 8 mg/mL. At sub-inhibitory concentrations (SICs), inhibited biofilm formation on glass surface, as evidenced by results microscope observations. Crystal violet staining assay cell enumeration revealed that also effective in inhibiting stainless steel surface....
Distant metastasis remains the primary cause of treatment failure and suggests a poor prognosis in nasopharyngeal carcinoma (NPC). Epithelial-mesenchymal transition (EMT) is critical cellular process for initiating tumor invasion remote metastasis. Our previous study showed that blockage stromal interaction molecule 1 (STIM1)-mediated Ca2+ signaling blunts Epstein-Barr virus (EBV)-promoted cell migration inhibits dissemination lymphatic NPC cells. However, upstream pathway regulates STIM1...