- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Organ Transplantation Techniques and Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Neuroblastoma Research and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Ovarian cancer diagnosis and treatment
- Liver Disease Diagnosis and Treatment
- Hernia repair and management
- Gallbladder and Bile Duct Disorders
- Pediatric Urology and Nephrology Studies
- Testicular diseases and treatments
- Neuroendocrine Tumor Research Advances
- Renal and related cancers
- Genetic and Kidney Cyst Diseases
- Renal cell carcinoma treatment
- Multiple and Secondary Primary Cancers
- Quantum Electrodynamics and Casimir Effect
- Genetic factors in colorectal cancer
- Congenital Anomalies and Fetal Surgery
- Whipple's Disease and Interleukins
- Vascular anomalies and interventions
- Surgical Simulation and Training
- Appendicitis Diagnosis and Management
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
2019-2024
Ministry of Health of the Russian Federation
2020-2024
National Research Center for Maternal and Child Health
2024
University Medical Center
2024
Russian Children's Clinical Hospital
2022-2023
Pirogov Russian National Research Medical University
2022-2023
Research Institute of Medical Climatology and Rehabilitation
2019
Lacrimal sac squamous cell carcinoma (SCC) is a rare tumor. Only 241 cases of lacrimal SCC have been reported in the literature. However, detailed molecular profile this tumor unknown.
Large and giant tumors, especially hepatoblastomas, are more frequently presented in pediatric patients. At about two-third of hepatoblastomas at the time diagnosis unresectable liver transplantation is considered as a treatment choice because insufficient future remnant volume. In selected cases, 2-staged hepatectomy may be unique chance for curative resection except followed by replacement. Despite overwhelming spread minimally invasive surgery, laparoscopic approach remains uncommon...
Aim. To carry out a retrospective analysis of the treatment outcomes patients who underwent liver resection with angioplasty facilitated by transplantation techniques. Materials and methods. The sample cases was divided into four groups: total vascular isolation liver, ante situm resection, hepatic artery portal vein reconstruction, cardiopulmonary bypass resection. focused on surgery features outcomes. Results. study involved 29 patients. performed interventions included 11 resections...
To present the experience of laparoscopic nephrectomies and kidney resections in children.
Progress in a modern pediatric oncological surgery, including neuroblastoma is characterized by increased role of the minimally-invasive approach. Authors represent standardized technical aspects abdominal laparoscopic resection. The purpose this research was to systematize resection for neuroblastoma, also cases with Image-Defined Risk Factors (IDRF). Methods used: pre- and intraoperative data 181 patients (85 (47%) males/96 (53%) females) median age 14 [5-51] (1-209) months old who had...
To analyze the initial data on future liver remnant volume and its function evaluated by 99mTc-Bromesida hepatobiliary scintigraphy in children with tumors.Extended resections were performed 58 patients aged 2 months - 208 (median 26 months) for various neoplasms. Before hepatectomy, all underwent contrast-enhanced CT volumetry 99mTc-Bromezida subsequent quantitative assessment of accumulation remnant. All consecutive eligible extended resection retrospectively analyzed.The analysis included...
Radical tumor removal remains the key task in hepatoblastoma surgery. Patients who need extended resection and have a risk of posthepatectomy liver failure are particularly difficult. In cases with insufficient future volume, method choice is two-staged hepatectomy or transplantation. Despite wide spread laparoscopic surgery adults, minimally invasive approach has not been studied pediatrics, literature on this issue scarce. current publication case successful partial associating partition...
• Laparoscopic extended right hepatectomy in children is a technically demanding, but feasible procedure. hepatectomies could be carried out selected patients centers, experienced both the liver and laparoscopic surgery. This video demonstrates laparoscopic-assisted for first time accomplished child teaches to more precisely plan procedure prefer or open approaches difficult cases.
In recent years сytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) became popular in pediatric oncologic surgery. This procedure is a “treatment of choice” for determined groups adult patients. The approaches preoperative diagnostics and surgical technique are well described patients, but not surgery, considering limited experience HIPEC children. review summarizes literature datas tumor dissemination, technical features peritonectomy based on localization analysis...
Over the past 2 decades minimally invasive liver resections have become preferable in tumors surgery adult patients. Indications for operations pediatric are actively extending, but number of such reports remains limited. The slow pace broad application laparoscopic hepatectomy children is explained, first all, by limited space abdominal cavity children, and lower prevalence population. This review analyzes evolution adults possibilities applying this experience to hepatic surgery.
Focal nodular hyperplasia (FNH) usually presents in children with underlying liver disease, patients undergone chemotherapy and adolescent females. The reports, describing huge FNH severe dilatation of the right hepatic vein (RHV) healthy are absent. A 2,7 years old boy without any comorbidities was presented intermittent abdominal pain a mass, causing asymmetry. initial imaging showed giant mass (more than 125 mm biggest dimensions), sings atypical It arising from 5,6 segments, accompanied...
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is treatment of choice for determined group adult patients. Cytoreduction and HIPEC usually used in patients ovarian, gastric colorectal cancer, appednix peritoneal mesothelioma some tumors another localization. The experience cytoreductive childhood limited due to the lower frequency carcinomatosis pediatric population. However, about 30% malignant children develop cavity pelvis. High recurrence rate are typical...
Aim. To analyze the short-term outcomes of сentral segments liver resection in children, according to initial experience. Мethods. The data patients with different centrally located neoplasms were analyzed. This retrospective study included three hepatoblastoma, one observation mesenchymal hamartoma and patient hepatocellular carcinoma. Different types central resections carried out these between March October 2018. technical aspects results are described. Results. Median age was 78 months...
Aim: to compare features of hepatocellular carcinoma (HCC) in children and adult patients assess the possibility translating experience treating pediatric oncology. Мethods: literature dedicated HCC investigation treatment has been analyzed. Pathomorphology, molecular-genetic disease, drug surgical approaches, particular immunotherapy liver transplantation were carefully compared both groups. Results: for analysis revealed that: fibrolamellar subtype as well large size primary tumor are more...
<h3></h3> Опухолевый тромбоз нижней полой вены и правого предсердия считают редким осложнением в детской солидной онкологии. Лечение таких пациентов сопряжено с высокими рисками осложнений неблагоприятного исхода, что требует мультидисциплинарного подхода использования высокотехнологичного оборудования на всех этапах комбинированного или комплексного лечения. На сегодняшний день не решен ряд вопросов, касающихся деталей оперативного вмешательства, подготовки к хирургическому лечению...
Risk-adapted therapy is the standard of care for hepatoblastoma (HB). The aim this study was to analyze effectiveness cisplatin monotherapy in patients with standard-risk HB. approved by Independent Ethics Committee and Scientific Council Dmitry Rogachev National Medical Research Center Pediatric Hematology, Oncology Immunology Ministry Healthcare Russian Federation. For period 02.2012–12.2019 (95 months) 60 HB aged 0–8 years were treated within framework cooperation Federation B.V....
Aim. To evaluate the relationship between future liver remnant volume and function determine possible threshold values of these parameters for predicting posthepatectomy failure in children. Methods. Data 57 patients who underwent major hepatectomy from July 2017 to February 2021 were retrospectively analyzed. Before surgery all children CT-volumetry 99mTc-Mebrofenin hepatobiliary scintigraphy. The considered 25%, 2.7%/min/m2 , respectively. After ISGLS 50–50 criteria assessed. principal...
The incidence of posthepatectomy liver failure in adult patients and a large number complications two-stage resections require search for criteria that allow highly accurate assessment the risk failure. For this purpose, study future remnant volume function have been widely introduced among patients, measurement reflects greater sensitivity. absence references to failure, as well experience determining functional reserve children, let us suggest possibility wider using one-stage when is...
Aim. To compare the results of laparoscopic and open resections in children with hepatic neoplasms. Materials methods. A retrospective analysis immediate long-term liver for period from 2018 to 2021 was performed. In order apply pseudorandomization, observations were compared according 10 cofounders, taking into account anamnestic data, anatomical physiological features. Results. 30 operated on laparoscopically 77 – by method. After 26 pairs comparable obtained. Statistically significant...
Peritoneal sarcomatosis/carcinomatosis is a rare observation in pediatric practice. It occurs, as rule, with various sarcomas, sarcomatoid tumors, desmoplastic small round cell tumors. Cytoreductive surgery followed by abdominal chemoperfusion has established itself an effective method of treating such conditions adult practice and gaining popularity Laparoscopic cytoreduction hyperthermic used patients number advantages: early recovery after surgery, reduced hospital days, timely initiation...