Preventing Chronic Disease (PCD) is a peer-reviewed electronic journal established by the National Center for Prevention and Health Promotion. PCD provides an open exchange of information knowledge among researchers, practitioners, policy makers, others who strive to improve health public through chronic disease prevention.

OBJECTIVE. The purpose of this study was to explore the value FDG PET combined with high-resolution CT (HRCT) in predicting pathologic subtypes and growth patterns early lung adenocarcinoma. MATERIALS AND METHODS. A retrospective analysis conducted on PET/CT data ground-glass nodules (GGNs) resected from patients stage IA efficacy maximum standardized uptake (SUVmax) HRCT signs prediction histopathologic subtype pattern adeno-carcinoma evaluated. RESULTS. SUVmax significantly higher GGNs...

Abstract To explore the values of C-reactive protein (CRP) and procalcitonin (PCT) in identifying infection disease activity systemic lupus erythematosus (SLE) patients. Patients with SLE from April 2015 to January 2018 were included this study. We compared clinical characteristics biomarkers between different groups calculated receiver operating characteristic curve, sensitivity, specificity corresponding biomarkers. Logistic regression analysis was performed on variables exhibiting...

This study aims to construct radiomics models based on [18F]FDG PET/CT using multiple machine learning methods predict the EGFR mutation status of lung adenocarcinoma and evaluate whether incorporating clinical parameters can improve performance models.A total 515 patients were retrospectively collected divided into a training set (n = 404) an independent testing 111) according their examination time. After semi-automatic segmentation images, features extracted, best feature sets CT, PET,...

Previous studies have reported that long non‑coding (lnc) RNA FGD5‑antisense 1 (FGD5‑AS1) promotes tumor proliferation, migration and invasion. Therefore, the present study aimed to elucidate biological role underlying molecular mechanisms of FGD5‑AS1 in cisplatin (DDP) resistance lung adenocarcinoma (LAD) cells. The results demonstrated was highly expressed DDP‑resistant LAD tissues Knockdown decreased proliferative, migratory invasive abilities Moreover, it identified acted as a sponge for...

Abstract Background To introduce a three-dimensional convolutional neural network (3D CNN) leveraging transfer learning for fusing PET/CT images and clinical data to predict EGFR mutation status in lung adenocarcinoma (LADC). Methods Retrospective from 516 LADC patients, encompassing preoperative images, information, status, were divided into training ( n = 404) test sets 112). Several deep models developed utilizing learning, involving CT-only PET-only models. A dual-stream model PET CT...

OBJECTIVE. The purpose of this study is to evaluate high-resolution CT (HRCT) combined with PET/CT for preoperative differentiation invasive adenocarcinoma (IAC) from preinvasive lesions and minimally (MIA) (the combination which hereafter referred as preinvasive-MIA) in lung manifesting ground-glass opacity nodules (GGNs) 3 cm or smaller. MATERIALS AND METHODS. We retrospectively analyzed the data patients GGNs that were smaller between November 2011 2018. HRCT parameters compared...

To explore the relationship between insulin resistance and osteoporosis risk in Chinese patients with type 2 diabetes mellitus (T2DM).A total of 234 T2DM were retrospectively analyzed, their lumbar bone mineral density (BMD) using C-peptide-based homeostasis model [HOMA-IR (CP)] assessed. Univariate multivariable logistic regression methods used to evaluate association HOMA-IR (CP) osteoporosis, subgroup analysis was performed on female male patients.After fully adjusting covariates, only...

The current commonly used treatments for cesarean scar pregnancy (CSP) include multiple such as medication, uterine artery embolization, curettage and surgery, their combinations. However, every treatment option has risks of excessive hemorrhage from uterus. In this study, we retrospectively analyzed the risk factors intraoperative different CSP patients, with hope to provide guidance treatment. Fifty-eight cases patients who were treated after or surgery compared clinical efficacy, length...

The aim of the present study was to investigate predictive value procalcitonin (PCT) for infection in patients with type 2 diabetes mellitus (T2DM). A retrospective analysis 178 T2DM who were divided into non-infection, local and sepsis groups conducted; conjunction 33 healthy control patients. Clinicopathological characteristics inflammatory indicators compared between four groups. Patients non-infection group exhibited significantly higher PCT levels controls (P=0.002). In addition, PCT,...

Abstract Background To establish and validate 18 F-fluorodeoxyglucose ( F-FDG) PET/CT-based radiomics model use it to predict the intermediate-high risk growth patterns in early invasive adenocarcinoma (IAC). Methods Ninety-three ground-glass nodules (GGNs) from 91 patients with stage I who underwent a preoperative F-FDG PET/CT scan histopathological examination were included this study. The LIFEx software was used extract 52 PET 49 CT radiomic features. least absolute shrinkage selection...

Severe burn sepsis can lead to high mortality. We explored the valuable prognostic indicators for severe with inhalation lesion.Thirty-eight patients who were admitted Third Affiliated Hospital of Soochow University from August 2014 December 2017 retrospectively analyzed. Among them, 22 assigned death group and 16 survival group. Their general information, vital signs, blood index including serum procalcitonin (PCT) C-reactive protein (CRP) levels at admission, diagnosis sepsis, 1-week...

Chest X-ray is a "golden standard" for the diagnosis and severity assessment of community-acquired pneumonia (CAP). However, it cannot be used as routine examination CAP in children. The present study aims to investigate roles prealbumin (PA) children further determine usefulness PA This was retrospective analysis 174 cases hospitalized with CAP. following indicators were recorded: vital sign, inflammatory indexes, PA, respiratory pathogens immunoglobulin M antibody test results. A total 33...

(1) Background: To investigate the association between maximum standardized uptake value (SUVmax) based on 18F-FDG PET/CT and EGFR mutation status in lung adenocarcinoma. (2) Methods: A total of 366 patients were retrospectively collected divided into group (n = 228) wild-type 138) according to their status. The two groups' general information imaging parameters compared. hierarchical binary logistic regression model was used assess interaction effect relationship SUVmax different subgroups....

Objective The purpose of this study was to investigate the effect two‐step irradiance schedule in relieving pain during PDT CA. Methods a prospective, controlled trial 141 CA patients who were randomly divided into Group A (two‐step schedule) and B (single‐dose cold compress). numeric rating scales (NRS) patients’ recorded at 5, 10, 15, 20 minutes each PDT. Results efficacy NRS scores two groups compared. There no significant difference gender, age, lesion site, disease course between ( P...

To investigate the early diagnostic and prognostic value of microRNA-1 in patients with acute chest pain. This study enrolled 341 attacked by pain within 3 h, another 100 volunteers as control group. Circulating was collected determined real-time quantitative reverse transcription-polymerase chain reaction. The clinical follow-up period 720 days. There were 174 myocardial infarction (AMI) group, 167 non-AMI relative expression significantly increased h AMI it continued rising 12 lower at 24...

Objective To investigate the high metabolic characteristics of uterine fibroids in fluorine-18 fluorodeoxyglucose (18F-FDG) PET/computed tomographic imaging and underlying mechanisms. Materials methods A total 47 patients with who underwent ultrasound examination from November 2011 to May 2015 were retrospectively analyzed. The 18F-FDG uptake by analyzed their correlations age, menopause, menstrual cycle, hormone indexes, tumor markers as well number maximum diameter images explored using...

Nonalcoholic fatty liver disease (NAFLD) is a multisystem that affects the and variety of extra-hepatic organ systems. This study aimed to investigate relationship between hepatic steatosis glucose metabolism in tissues organs.