Anita Dhanrajani
A5015250606- Kawasaki Disease and Coronary Complications
- Autoimmune and Inflammatory Disorders Research
- Cardiovascular Issues in Pregnancy
- Musculoskeletal Disorders and Rehabilitation
- Coronary Artery Anomalies
- Respiratory viral infections research
- Mechanical Circulatory Support Devices
- Innovations in Medical Education
- Streptococcal Infections and Treatments
- Inflammasome and immune disorders
- Lymphadenopathy Diagnosis and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Full-Duplex Wireless Communications
- COVID-19 Clinical Research Studies
- Clinical Reasoning and Diagnostic Skills
- Rheumatoid Arthritis Research and Therapies
- COVID-19 Impact on Reproduction
- Child and Adolescent Health
- Ocular Diseases and Behçet’s Syndrome
- IL-33, ST2, and ILC Pathways
- Bacterial Infections and Vaccines
- CNS Lymphoma Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Adolescent and Pediatric Healthcare
- COVID-19 epidemiological studies
University of Mississippi Medical Center
2022-2025
Tulane University
2023-2025
Children's Hospital of New Orleans
2023-2024
Jackson Memorial Hospital
2022
University of Mississippi
2022
Hospital for Sick Children
2017-2020
Great Ormond Street Hospital
2017-2020
University College London
2017-2020
SickKids Foundation
2017-2020
University of British Columbia
2017
Multisystem inflammatory syndrome in children (MIS-C) is a severe postinfectious hyperinflammatory condition, which generally occurs 2-6 weeks after typically mild or asymptomatic infection with SARS-CoV-2, the virus that causes COVID-19 (1-3). In United States, BNT162b2 (Pfizer-BioNTech) vaccine currently authorized for use and adolescents aged 5-15 years under an Emergency Use Authorization fully licensed by Food Drug Administration persons ≥16 (4). Prelicensure randomized trials ≥5...
Acetylsalicylic acid (ASA) is part of the recommended treatment Kawasaki disease (KD). Controversies remain regarding optimal dose ASA to be used. We aimed evaluate noninferiority at an antiplatelet in acute KD preventing coronary artery (CA) abnormalities.This a multicenter, retrospective, nonrandomized cohort study including children 0 10 years age with between 2004 and 2015 from 5 institutions, which 2 routinely use low-dose (3-5 mg/kg per day) 3 high-dose (80 day). Outcomes were CA...
To characterize the clinical, demographic, and socioeconomic profile of childhood systemic lupus erythematous (cSLE) in Black Belt Southern United States comparison to current literature predominantly Caucasian cohorts. This is a cross-sectional study characterizing patients with cSLE from two centers Southeastern States- University Mississippi Medical Center (UMMC) Alabama at Birmingham (UAB). Demographic, social, clinical data was retrospectively collected by medical chart review for...
Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients.We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted the intensive care or high-acuity unit with COVID-19. Using mixed-effects models, we assessed odds death requiring life support for COVID-19 after adjustment age, sex, race Hispanic origin, underlying conditions...
Kawasaki disease (KD) is an acute childhood vasculitis that may result in coronary aneurysms. Treatment of KD with a single infusion 2 gm/kg intravenous immunoglobulin (IVIG) well established, but acetylsalicylic acid (ASA) dose remains controversial. Our primary objective was to determine the difference incidence IVIG resistance between ASA doses. secondary compare duration hospital stay and artery aneurysm.We reviewed charts patients from Canadian centers assess impact on (operationally...
Introduction: Gain-of-function mutations in TMEM173 encoding STING (Stimulator of Interferon Genes) underlie a novel type I interferonopathy, minimally responsive to conventional immunosuppressive therapies and associated with high childhood morbidity mortality.A newly emerging treatment strategy STING-related inflammation aims control interferon (IFN) signalling post-binding the IFN receptor, by targeting JAK1/2.We hypothesized that inhibition production itself might represent an...
Minimal data are available regarding the postdischarge treatment of multisystem inflammatory syndrome in children (MIS-C).To evaluate clinical characteristics associated with duration glucocorticoid use and assess course, laboratory test result trajectories, adverse events a multicenter cohort MIS-C.This retrospective study included patients MIS-C hospitalized severe illness followed up for 3 months an ambulatory setting. Patients younger than 21 years who were admitted between May 15, 2020,...
Racial disparities in SARS-CoV-2 infection, hospitalization, and multisystem inflammatory syndrome children (MIS-C) have been reported. However, these reports based on incomplete data relying passive reporting, unknown catchment populations, infection prevalence. We aimed to characterize population-based incidence of MIS-C COVID-19 hospitalizations among non-Hispanic Black White using active surveillance seroprevalence-based cumulative pediatric a defined 16-county area Mississippi.
Abstract Background Intraarticular injections (IAI) were first reported in adult rheumatology the 1950s and subsequently gained acceptance as a safe efficacious treatment Juvenile idiopathic arthritis (JIA). IAIs are now widely performed recommended initial or only of oligoarticular JIA ancillary actively inflamed joints other varieties JIA. However, performance procedure is currently not guided by standardized recommendations, several practice variations observed. Methods This worldwide...
Chronic anterior uveitis (CAU) carries a significant risk for eye complications and vision loss. The Childhood Arthritis Rheumatology Research Alliance (CARRA) introduced consensus treatment plans (CTPs) to standardize CAU facilitate future comparative effectiveness studies. Two CTPs were developed address: 1) initiation of methotrexate (MTX) in patients with naïve steroid-sparing therapy, 2) TNF inhibitor (TNFi) severe or refractory MTX. We evaluated implementation the using existing CARRA...
Abstract Aims To explore knowledge, attitudes, and practices relating to musculoskeletal examination (MSKe) in one state of India. Methods Pediatricians from the Maharashtra (capital – Mumbai) were invited complete an 11-item web-based survey. Participation implied consent survey was based on a similar UK study. All pediatricians ( n = 1523) participate; 223 responded (response rate: 14.64%) with variable training pediatrics experience. Results Respondents reported time devoted within their...
Musculoskeletal examination(MSKe) is a neglected clinical skill in paediatric practice and this could contribute to delayed or missed rheumatologic diagnosis children. Gait Arms Legs Spine (pGALS), simple format of MSKe, targeted at non specialists has been shown be acceptable valid. Its potential as tool populations underserved by rheumatologists, such India, yet explored. This information used design curricula teaching methods students practitioners areas.
The occurrence of Erythema Multiforme (EM) like lesions in lupus has been reported 98 patients to date but only 9 children below 18 years.
Abstract Background: Intraarticular injections (IAI) were first reported in adult rheumatology the 1950s and subsequently gained acceptance as a safe efficacious treatment Juvenile Idiopathic arthritis (JIA). IAIs are now widely performed recommended initial or only of Oligoarticular JIA ancillary actively inflamed joints other varieties JIA. However, performance procedure is not currently guided by standardized recommendations, thereby several practice variations observed.Methods: This...
Background: Racial disparities in SARS-CoV-2-infection, hospitalization, and multi-system inflammatory syndrome children (MIS-C) have been widely reported. However, these reports based on incomplete data relying passive reporting, unknown catchment populations, infection prevalence. We aimed to characterize population-based incidence of MIS-C acute COVID-19 among non-Hispanic Black White using active surveillance cumulative pediatric SARS-CoV-2 a tightly defined 16-county area, including...