Mary Glas Gaspers
A5008823365- Kawasaki Disease and Coronary Complications
- COVID-19 Impact on Reproduction
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
- Neurological Complications and Syndromes
- Blood Coagulation and Thrombosis Mechanisms
- Mechanical Circulatory Support Devices
- Respiratory Support and Mechanisms
- COVID-19 and Mental Health
- Airway Management and Intubation Techniques
- Congenital Diaphragmatic Hernia Studies
- Ethics and Legal Issues in Pediatric Healthcare
- Influenza Virus Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Child and Adolescent Health
- Pregnancy and Medication Impact
- Clinical Nutrition and Gastroenterology
- Forensic Toxicology and Drug Analysis
- Cardiac Structural Anomalies and Repair
- Healthcare cost, quality, practices
- Bacterial Infections and Vaccines
- Tracheal and airway disorders
Children's Medical Center
2022-2025
Banner - University Medical Center Tucson
2018-2023
Johns Hopkins Medicine
2023
Johns Hopkins University
2023
University of Arizona
2015-2023
Banner Children's at Desert
2023
Cincinnati Children's Hospital Medical Center
2021
University of Cincinnati
2021
Coronavirus disease 2019 (COVID-19) affects the nervous system in adult patients. The spectrum of neurologic involvement children and adolescents is unclear.To understand range severity among associated with COVID-19.Case series patients (age <21 years) hospitalized between March 15, 2020, December positive severe acute respiratory syndrome coronavirus 2 test result (reverse transcriptase-polymerase chain reaction and/or antibody) at 61 US hospitals Overcoming COVID-19 public health...
Multisystem inflammatory syndrome in children (MIS-C) is a severe postinfectious hyperinflammatory condition, which generally occurs 2-6 weeks after typically mild or asymptomatic infection with SARS-CoV-2, the virus that causes COVID-19 (1-3). In United States, BNT162b2 (Pfizer-BioNTech) vaccine currently authorized for use and adolescents aged 5-15 years under an Emergency Use Authorization fully licensed by Food Drug Administration persons ≥16 (4). Prelicensure randomized trials ≥5...
COVID-19 vaccination is recommended for persons who are pregnant, breastfeeding, trying to get pregnant now, or might become in the future, protect them from COVID-19.§ Infants at risk life-threatening complications COVID-19, including acute respiratory failure (1). Evidence other vaccine-preventable diseases suggests that maternal immunization can provide protection infants, especially during high-risk first 6 months of life, through passive transplacental antibody transfer (2). Recent...
The increasing incidence of pediatric hospitalizations associated with coronavirus disease 2019 (Covid-19) caused by the B.1.617.2 (delta) variant severe acute respiratory syndrome 2 (SARS-CoV-2) in United States has offered an opportunity to assess real-world effectiveness BNT162b2 messenger RNA vaccine adolescents between 12 and 18 years age.
Pfizer-BioNTech COVID-19 vaccine is authorized for use in children and adolescents aged 12-15 years licensed by the Food Drug Administration (FDA) persons ≥16 (1). A randomized placebo-controlled trial demonstrated an efficacy of 100% (95% confidence interval [CI] = 75.3%-100%) preventing outpatient (2); however, data among on effectiveness (VE) against real-world settings are limited, especially hospitalized patients. In early September 2021, U.S. pediatric hospitalizations reached highest...
Importance Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infections (LRTIs) and infant hospitalization worldwide. Objective To evaluate characteristics outcomes RSV-related critical illness in US infants during peak 2022 RSV transmission. Design, Setting, Participants This cross-sectional study used a public health prospective surveillance registry 39 pediatric hospitals across 27 states. were admitted for 24 or more hours between October 17 December 16,...
Multisystem inflammatory syndrome in children (MIS-C), linked to antecedent severe acute respiratory coronavirus 2 (SARS-CoV-2) infection, is associated with considerable morbidity. Prevention of SARS-CoV-2 infection or disease 2019 (COVID-19) by vaccination might also decrease MIS-C likelihood.In a multicenter, case-control, public health investigation ages 5-18 years hospitalized from 1 July 2021 7 April 2022, we compared the odds being fully vaccinated (2 doses BNT162b2 vaccine ≥28 days...
To evaluate risk factors for postdischarge sequelae in children and adolescents hospitalized acute coronavirus disease 2019 (COVID-19) or multisystem inflammatory syndrome (MIS-C).Multicenter prospective cohort study conducted 25 United States pediatric hospitals. Patients <21-years-old, May 2020 to 2021 COVID-19 MIS-C with follow-up 2 4 months after admission. We assessed readmissions, persistent symptoms activity impairment, new morbidities. Multivariable regression was used calculate...
OBJECTIVES: Extracorporeal membrane oxygenation (ECMO) has been used successfully to support adults with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related cardiac or failure refractory conventional therapies. Comprehensive reports of children and adolescents SARS-CoV-2–related ECMO for conditions, including multisystem inflammatory in (MIS-C) COVID-19, are needed. DESIGN: Case series patients from the Overcoming COVID-19 public health surveillance registry. SETTING:...
Importance In 2020 during the COVID-19 pandemic, neurologic involvement was common in children and adolescents hospitalized United States for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–related complications. Objective To provide an update on spectrum of SARS-CoV-2–related among 2021. Design, Setting, Participants Case series investigation patients reported to public health surveillance with illness between December 15, 2020, 31, 2021, 55 US hospitals 31 states follow-up at...
Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients.We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted the intensive care or high-acuity unit with COVID-19. Using mixed-effects models, we assessed odds death requiring life support for COVID-19 after adjustment age, sex, race Hispanic origin, underlying conditions...
Pediatric respiratory syncytial virus (RSV)-related acute lower tract infection (LRTI) commonly requires hospitalization. The Clinical Progression Scale Pediatrics (CPS-Ped) measures level of support and degree hypoxia across a range disease severity, but it has not been applied in infants hospitalized with severe RSV-LRTI. We analyzed data from prospective surveillance registry for RSV-related complications 39 U.S. PICUs October through December 2022. assigned CPS-Ped (0=discharged home at...
With rapid and accurate molecular influenza testing now widely available in clinical settings, vaccine effectiveness (VE) studies can prospectively select participants for enrollment based on real-time results rather than enrolling all eligible patients regardless of status, as the traditional test-negative design (TND). Thus, we explore advantages disadvantages modifying TND estimating VE by using real-time, clinically viral paired with acute respiratory infection eligibility criteria...
Introduction Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) is a network fostering clinical research to optimize care for critically ill children. We aim examine the efforts of PALISI Network increase gender parity in research, as evidenced by authorship. Methods The first senior authors all published articles from 2002 2021 were analyzed presentation. Funding sources, impact factors, professional roles, location extracted. Results identified 303 articles, 61 2011, 242 2012...
Adolescent use of illicit substances remains a significant problem. In attempts to hide their these substances, some are using Internet-recommended methods masking drugs on drug screens, potentially exposing the adolescent severe and possibly dangerous adverse effects. We report 16-year-old patient who ingested approximately 13 g (twenty-six 500-mg tablets) niacin during 48-hour period in an attempt mask his tetrahydrocannabinol upcoming screen. He subsequently developed chest abdominal pain...
Abstract Background We aimed to determine if pre-existing immunocompromising conditions (ICCs) were associated with the presentation or outcome of patients acute coronavirus disease 2019 (COVID-19) admitted for pediatric intensive care. Methods Fifty-five hospitals in 30 US states reported cases through Overcoming COVID-19 public health surveillance registry. Patients &lt;21 years 12 March 2020–30 December 2021 care unit (PICU) high-acuity included. Results Of 1274 patients, 105 (8.2%)...
Copyright © by 2015 the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
1. Ahmeneh Ghavam, MD* 2. Mary Gaspers, MD, MPH* 1. *Department of Pediatric Critical Care, University Arizona, Tucson, AZ. A 35-month-old boy presents with history vomiting and unsteady gait. Earlier today at daycare he had several episodes emesis, developed an gait, stated did not feel well. Later home, his parents noted that continued to vomit became difficult arouse. He have any seizures, but the report some erratic eye movements. There is no known head trauma, medication...
Copyright © 2016 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
A 35-month-old boy presents with history of vomiting and unsteady gait. Earlier today at daycare he had several episodes emesis, developed an gait, stated did not feel well. Later home, his parents noted that continued to vomit became difficult arouse. He have any seizures, but the report some erratic eye movements. There is no known head trauma, medication ingestions, or exposure toxic substances.On physical examination, unresponsive breathing spontaneously. Vital signs include: temperature...
Introduction: The proportion of women in the field pediatric critical care medicine is increasing. Founded 2002, PALISI a network which fosters clinically relevant research to optimize critically ill children. We aim examine efforts increase gender parity science as evidenced by authorship its works. Methods: All published articles from 2002 - 2021 were analyzed for presentation both first and senior author. Funding sources, corresponding authors, professional role, geographical location...
Pfizer-BioNTech COVID-19 vaccine received emergency use authorization for persons ≥ 16 years in December 2020 and adolescents 12-15 May 2021. Despite the clear benefits favorable safety profile, uptake has been suboptimal. We sought to assess factors associated with non-vaccination 12-18 of age.Between June 1, 2021 April 29, 2022, we assessed hospitalized ages enrolled Overcoming effectiveness network. Demographic characteristics clinical information were captured through parent interviews...