Becky J. Riggs
A5009838528- Traumatic Brain Injury and Neurovascular Disturbances
- Kawasaki Disease and Coronary Complications
- COVID-19 Clinical Research Studies
- Neonatal and fetal brain pathology
- Cardiac Arrest and Resuscitation
- COVID-19 Impact on Reproduction
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Intraocular Surgery and Lenses
- Ultrasound in Clinical Applications
- Mechanical Circulatory Support Devices
- Cerebral Venous Sinus Thrombosis
- Long-Term Effects of COVID-19
- Renal and Vascular Pathologies
- Traumatic Ocular and Foreign Body Injuries
- COVID-19 and Mental Health
- Intraoperative Neuromonitoring and Anesthetic Effects
- Child Abuse and Related Trauma
- Neonatal Respiratory Health Research
- Organ Donation and Transplantation
- Acute Ischemic Stroke Management
- Restraint-Related Deaths
- Olfactory and Sensory Function Studies
- Nosocomial Infections in ICU
- Pediatric Pain Management Techniques
Johns Hopkins University
2015-2025
Doernbecher Children's Hospital
2022-2025
Children's National
2013-2025
Johns Hopkins Medicine
2015-2024
Oregon Health & Science University
2022-2024
Bloomberg (United States)
2017-2022
Centers for Disease Control and Prevention
2022
Children's Center
2022
Texas Children's Hospital
2021
Johns Hopkins Children's Center
2017-2020
Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) its temporal association with coronavirus disease 2019 (Covid-19) is important, given public health implications syndrome. We conducted targeted surveillance for MIS-C from March 15 to May 20, 2020, pediatric centers across United States. The case definition included six criteria: serious illness leading hospitalization, an age less than 21 years, fever that lasted at least 24 hours,...
The recent and ongoing coronavirus disease 2019 (COVID-19) pandemic has taken an unprecedented toll on adults critically ill with COVID-19 infection. While there is evidence that the burden of infection in hospitalized children lesser than their adult counterparts, to date, are only limited reports describing pediatric intensive care units (PICUs).
<h3>Importance</h3> Refinement of criteria for multisystem inflammatory syndrome in children (MIS-C) may inform efforts to improve health outcomes. <h3>Objective</h3> To compare clinical characteristics and outcomes adolescents with MIS-C vs those severe coronavirus disease 2019 (COVID-19). <h3>Setting, Design, Participants</h3> Case series 1116 patients aged younger than 21 years hospitalized between March 15 October 31, 2020, at 66 US hospitals 31 states. Final date follow-up was January...
Coronavirus disease 2019 (COVID-19) affects the nervous system in adult patients. The spectrum of neurologic involvement children and adolescents is unclear.To understand range severity among associated with COVID-19.Case series patients (age <21 years) hospitalized between March 15, 2020, December positive severe acute respiratory syndrome coronavirus 2 test result (reverse transcriptase-polymerase chain reaction and/or antibody) at 61 US hospitals Overcoming COVID-19 public health...
The assessment of real-world effectiveness immunomodulatory medications for multisystem inflammatory syndrome in children (MIS-C) may guide therapy.
Sensitive, specific, and safe bedside evaluation of brain perfusion is key to the early diagnosis, treatment, improved survival neonates with hypoxic ischemic injury. Contrast‐enhanced ultrasound (US) imaging a novel technique in which intravenously injected gas‐filled microbubbles generate enhanced US echoes from an acoustic impedance mismatch. This article describes contrast‐enhanced 2 injury future directions on developing quantitative techniques for characterization abnormalities. The...
Objectives To investigate whether quantitative contrast‐enhanced ultrasound (CEUS) can accurately identify neonates and infants with hypoxic ischemic brain injury. Methods In this prospective cohort study, 8 a suspicion of injury were evaluated CEUS. Results An interesting trend was observed in the central gray nuclei–to–cortex perfusion ratios. The ratios at peak enhancement, wash‐in area under curve, index, maximum slopes lower all affected cases compared to normal group but not...
Multisystem inflammatory syndrome in children (MIS-C) consensus criteria were designed for maximal sensitivity and therefore capture patients with acute COVID-19 pneumonia.We performed unsupervised clustering on data from 1,526 (684 labeled MIS-C by clinicians) <21 years old hospitalized COVID-19-related illness admitted between 15 March 2020 31 December 2020. We compared prevalence of assigned labels clinical features among clusters, followed recursive feature elimination to identify...
Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients.We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted the intensive care or high-acuity unit with COVID-19. Using mixed-effects models, we assessed odds death requiring life support for COVID-19 after adjustment age, sex, race Hispanic origin, underlying conditions...
Multisystem inflammatory syndrome in children (MIS-C) is a postinfectious severe acute respiratory coronavirus 2 (SARS-CoV-2)-related complication that has disproportionately affected racial/ethnic minority children. We conducted pilot study to investigate risk factors for MIS-C aiming understand disparities.This case-control included cases and SARS-CoV-2-positive outpatient controls less than 18 years old frequency-matched 4:1 by age group site. Patients hospitalized with were admitted...
We describe the process converting half of our 40-bed PICU into a negative-pressure biocontainment ICU dedicated to adult coronavirus disease 2019 patients within 1,003-bed academic quaternary hospital. outline construction, logistics, supplies, provider education, staffing, and operations. share lessons learned working with predominantly pediatric staff blended expertise while maintaining elements family-centered care typical critical medicine. Critically ill may be cared for in augmented...
Imaging diagnosis of brain death is performed with either four-vessel cerebral angiography or radionuclide blood flow studies. Unfortunately, timely performance study at a critically ill period not only cumbersome but feasible in many cases. We present case 6-month-old male three hours status post-cardiac arrest unknown etiology who underwent contrast-enhanced ultrasound (CEUS) for near absent perfusion, death. The patient passed away 30 minutes after the exam and clinical was confirmed....
Abstract Background Community-onset bacterial coinfection in adults hospitalized with coronavirus disease 2019 (COVID-19) is reportedly uncommon, though empiric antibiotic use has been high. However, data regarding and children critical illness from COVID-19 are scarce. Methods We evaluated adolescents aged &lt;19 years admitted to a pediatric intensive care or high-acuity unit for between March December 2020. Based on qualifying microbiology results the first 3 days of admission, we...
Objective: The purpose of this observational study is to explore if bedside Doppler ultrasonography the central retinal vessels has potential become an ancillary support timely diagnosis brain death in children. Design: Seventeen-month prospective cohort. Setting: Forty-four bed pediatric medical and surgical ICU academic teaching hospital. Patients: All children 0–18 years old who were clinically evaluated for at Children’s National Health Systems enrolled followed until discharge or death....
Background: Childhood stroke is rare, and diagnosis frequently delayed. The use of pediatric teams has the potential to decrease time neurology evaluation imaging, hastening appropriate treatment for acute neurologic presentations in children. Methods: We performed a retrospective analysis our institutional or “brain attack” team (pedsBAT) activations from October 2014 July 2017. Clinical characteristics timing parameters were compared between pedsBAT inpatient vs emergency department (ED) /...
Abstract We evaluated the use of quantitative contrast-enhanced ultrasound (CEUS) to study wash-out behavior contrast agents in pediatric brain cases hypoxic ischemic injury (HII). Six neonates and young infants were imaged using CEUS for suspected HII Neonatal Intensive Care Unit/Pediatric Unit. After receiving a bolus agent Lumason (Bracco Diagnostics Inc.), analysis was performed whole brain, cortex, cortical/subcortical gray white matter central nuclei quantify metrics ratios. On...