A5084123774- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Intensive Care Unit Cognitive Disorders
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Thermal Regulation in Medicine
- Acute Ischemic Stroke Management
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Intracerebral and Subarachnoid Hemorrhage Research
- Sepsis Diagnosis and Treatment
- Psychosomatic Disorders and Their Treatments
- Epilepsy research and treatment
- Airway Management and Intubation Techniques
- Neurosurgical Procedures and Complications
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Tracheal and airway disorders
- Intracranial Aneurysms: Treatment and Complications
- Disaster Response and Management
- Pharmacological Effects and Toxicity Studies
- Heart Rate Variability and Autonomic Control
- Venous Thromboembolism Diagnosis and Management
- Non-Invasive Vital Sign Monitoring
Maine Medical Center
2016-2025
Tufts University
2012-2025
Maine Medical Center
2014-2025
MaineHealth
2022-2025
Columbia University
2008-2024
Presbyterian Hospital
2024
New York Hospital Queens
2024
NewYork–Presbyterian Hospital
2024
University of North Carolina at Chapel Hill
2023-2024
Maine Medical Center Research Institute
2019-2023
Many patients with severe stroke have impaired airway protective reflexes, resulting in prolonged invasive mechanical ventilation.To test whether early vs standard tracheostomy improved functional outcome among receiving ventilation.In this randomized clinical trial, 382 acute ischemic or hemorrhagic ventilation were randomly assigned (1:1) to (≤5 days of intubation) ongoing ventilator weaning if needed from day 10. Patients between July 28, 2015, and January 24, 2020, at 26 US German...
OBJECTIVE Transcranial Doppler (TCD) is widely used to monitor the temporal course of vasospasm after subarachnoid hemorrhage (SAH), but its ability predict clinical deterioration or infarction from delayed cerebral ischemia (DCI) remains controversial. We sought determine prognostic utility serial TCD examination SAH. METHODS analyzed 1877 examinations in 441 aneurysmal SAH patients within 14 days onset. The highest mean blood flow velocity (mBFV) value any vessel before DCI onset was...
To evaluate the outcomes of cardiac arrest survivors with myoclonus receiving modern postresuscitation care.Retrospective review registry data.Cardiac centers in Europe and United States from 2002 to 2012.Two thousand five hundred thirty-two 18 years or older enrolled International Cardiac Arrest Registry.None.Eighty-eight percent patients underwent therapeutic hypothermia 471 (18%) exhibited myoclonus. Patients had longer time professional cardiopulmonary resuscitation (8.6 vs 7.0 min; p <...
Background: The benefit of emergency coronary angiography after resuscitation from out-of-hospital cardiac arrest is uncertain for patients without ST-segment elevation. aim this randomized trial was to evaluate the efficacy and safety early determine prevalence acute occlusion in resuscitated with Methods: Adult (>18 years) comatose survivors elevation were prospectively a 1:1 fashion under exception informed consent regulations versus no multicenter study. Early defined as ≤120 minutes...
Previous studies have suggested an effect of gender on outcome after out-of-hospital cardiac arrest (OHCA), but the results are conflicting. We aimed to investigate association outcome, coronary angiography (CAG) and adverse events in OHCA survivors treated with mild induced hypothermia (MIH). performed a retrospective analysis prospectively collected data from International Cardiac Arrest Registry. Adult patients non-traumatic MIH were included. Good neurological was defined as cerebral...
Importance Understanding the relationship between patients’ clinical characteristics and outcomes is fundamental to medicine. When critically ill patients die after withdrawal of life-sustaining therapy (WLST), inability observe potential for recovery with continued aggressive care could bias future decisions research. Objective To quantify frequency which experts consider who died WLST following resuscitated cardiac arrest have had if been continued. Design, Setting, Participants This...
Object The purpose of this study was to identify predictors shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH). Methods authors evaluated the incidence in a consecutive cohort 580 patients with SAH who were admitted Neurological Intensive Care Unit Columbia University Medical Center between July 1996 and September 2002. Patient demographics, 24-hour admission variables, initial CT scan characteristics, daily transcranial Doppler development in-hospital complications...
Objective: Retrospective analyses of several trials suggest etomidate may be unsafe for intubation in patients with sepsis. We evaluated the association and mortality a large cohort septic to determine if single-dose was associated increased in-hospital mortality. Design Setting: study at Philips eICU Research Institute ICU clinical database. Interventions: None. Patients: Among 741,036 monitored from 2008 through 2010, we identified 2,014 adults intubated 4–96 hrs after admission, having...
Early reports of coronavirus disease 2019 (COVID-19) clinical features describe a hypercoagulable state, and recent guidelines recommend prophylactic anticoagulation for patients with COVID-19 low-molecular-weight heparin, but this would be contraindicated in the presence heparin-induced thrombocytopenia (HIT). We address key question whether HIT is also present during COVID-19. report 3 cases antiplatelet factor 4 antibodies among 16 intubated adult respiratory distress syndrome,...
The critical care management of patients after cardiac arrest is burdened by a lack high-quality clinical studies and the resultant high-certainty evidence. This results in limited practice guideline recommendations, which may lead to uncertainty variability management. Critical crucial affects outcome. Although guidelines address some relevant topics (including temperature control neurological prognostication comatose survivors, 2 for there are more robust studies), many important subject...