A5025187633- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Intracranial Aneurysms: Treatment and Complications
- Thermal Regulation in Medicine
- Respiratory Support and Mechanisms
- Cerebrovascular and Carotid Artery Diseases
- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Cerebrospinal fluid and hydrocephalus
- Stroke Rehabilitation and Recovery
- Palliative Care and End-of-Life Issues
- Epilepsy research and treatment
- Anesthesia and Sedative Agents
- COVID-19 Clinical Research Studies
- Anesthesia and Neurotoxicity Research
- Healthcare Decision-Making and Restraints
- Atrial Fibrillation Management and Outcomes
- Telemedicine and Telehealth Implementation
- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
Cooper University Hospital
2009-2025
Cooper University Health Care
2025
Cooper Medical School of Rowan University
2025
Rowan University
2023
Thomas Jefferson University Hospital
2012-2022
Portola Pharmaceuticals (United States)
2022
Thomas Jefferson University
2012-2021
Jefferson Hospital for Neuroscience
2012-2021
Neurological Surgery
2012-2020
Jefferson University Hospitals
2015-2020
Emergence of the novel corona virus (severe acute respiratory syndrome (SARS)-CoV-2) in December 2019 has led to COVID-19 pandemic. The extent involvement central nervous system is not well established, and presence or absence SARS-CoV-2 particles cerebrospinal fluid (CSF) a topic debate.We present two patients with concurrent neurological symptoms. Our first patient 31-year-old man who had flu-like symptoms due later developed an acute-onset severe headache loss consciousness was diagnosed...
The Society of Critical Care Medicine and four other major critical care organizations have endorsed a seven-step process to resolve disagreements about potentially inappropriate treatments. multiorganization statement (entitled: An official ATS/AACN/ACCP/ESICM/SCCM Policy Statement: Responding Requests for Potentially Inappropriate Treatments in Intensive Units) provides examples treatments; however, no clear definition is provided. This was developed provide interventions the ICU...
To test the hypothesis that hyperoxia was associated with higher in-hospital mortality in ventilated stroke patients admitted to ICU.Retrospective multicenter cohort study.Primary admissions of acute ischemic stroke, subarachnoid hemorrhage, and intracerebral hemorrhage who had arterial blood gases within 24 hours admission ICU at 84 U.S. ICUs between 2003 2008. Patients were divided into three exposure groups: defined as PaO2 ≥ 300 mm Hg (39.99 kPa), hypoxia any PaO2<60 (7.99 kPa) or...
BACKGROUND: Subarachnoid hemorrhage (SAH) is the cause of 5% to 10% strokes annually in United States. OBJECTIVE: To study incidence and mortality trends admissions SAH from 1979 2008 using a nationally representative sample all nonfederal acute-care hospitals States: The National Hospital Discharge Survey. METHODS: was obtained hospital discharge records according International Classification Disease, 9th Revision, Clinical Modification code 430. RESULTS: We reviewed data on approximately 1...
The authors sought to determine frequency, risk factors, and impact on outcome of asymptomatic cerebral infarction due vasospasm after subarachnoid hemorrhage (SAH).The prospectively studied 580 patients with SAH admitted their center between July 1996 May 2002. Delayed ischemia (DCI) from was defined as 1) a new focal neurological deficit or decrease in level consciousness, 2) infarct revealed by follow-up CT imaging, both, excluding causes other than vasospasm. Outcome at 3 months assessed...
<i>Background:</i> To assess the prevalence of risk factors as determinants intracranial atherosclerosis (IATH)-related stroke in a multi-ethnic community-based cohort. <i>Methods:</i> The Northern Manhattan Stroke Study included population-based incidence study and nested case-control study. Incident cases first ischemic were 1:2 when matched to community controls by age, sex, race/ethnicity. Vascular assessed among compared against following subtypes: IATH,...
Traumatic brain injury (TBI) is a major cause of disability, morbidity, and mortality. The effect the acute respiratory distress syndrome lung (ARDS/ALI) on in-hospital mortality after TBI remains controversial.To determine epidemiology ARDS/ALI, prevalence risk factors, impact in United States.Retrospective cohort study admissions adult patients>18 years with diagnosis ARDS/ALI from 1988 to 2008 identified through Nationwide Inpatient Sample.During 20-year period, increased 2% (95%...
<h3>Objective</h3> In this retrospective multi-centre cohort study, we tested the hypothesis that hyperoxia was not associated with higher in-hospital case fatality in ventilated traumatic brain injury (TBI) patients admitted to intensive care unit (ICU). <h3>Methods</h3> Admissions of TBI who had arterial blood gases within 24 h admission ICU at 61 US hospitals between 2003 and 2008 were identified. Hyperoxia defined as PaO<sub>2</sub> ≥300 mm Hg (39.99 kPa), hypoxia any <60 (7.99 kPa)...
In 2014, the Tele-ICU Committee of Society Critical Care Medicine published an article regarding state ICU telemedicine, one better defined today as tele-critical care. Given rapid evolution in field, authors now provide updated review.
Serious cardiac arrhythmias have been described in approximately 5% of patients after subarachnoid hemorrhage (SAH). The aim this study was to identify the frequency, risk factors and clinical impact arrhythmia SAH. We prospectively studied 580 spontaneous SAH identified complications associated with development clinically significant arrhythmia. Multiple logistic regression analysis used calculate adjusted odds ratios for effect on hospital 3-month outcome, as measured by modified Rankin...
Object The purpose of this study was to identify predictors shunt-dependent hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH). Methods authors evaluated the incidence in a consecutive cohort 580 patients with SAH who were admitted Neurological Intensive Care Unit Columbia University Medical Center between July 1996 and September 2002. Patient demographics, 24-hour admission variables, initial CT scan characteristics, daily transcranial Doppler development in-hospital complications...
The aim of this study was describe national trends in prevalence, demographics, hospital length stay (LOS), charges, and mortality for burn patients with without inhalational injury to compare the National Burn Repository. Burns inhalation cause considerable morbidity United States. There remains insufficient reporting demographics outcomes surrounding such injuries. Inpatient Sample database, nation's largest all-payer inpatient care data repository, utilized select 506,628 admissions burns...
RNA sequencing of cerebral hematoma myeloid cells reveals a two-stage functional and metabolic program associated with recovery.
Cardiac mortality after stroke is common, and small studies have suggested an association of short-term cardiac with insular location cerebral infarction. Few population-based long-term follow-up evaluated the effect on risk death or myocardial infarction (MI) first ischemic stroke. We sought to determine between MI in a multiethnic community-based cohort.