Mengke Ni

ORCID: 0000-0002-5741-6600
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Research Areas
  • Diet and metabolism studies
  • Rabbits: Nutrition, Reproduction, Health
  • Gut microbiota and health
  • Molecular Biology Techniques and Applications
  • Virus-based gene therapy research
  • Animal Nutrition and Physiology
  • Adipose Tissue and Metabolism
  • Ruminant Nutrition and Digestive Physiology
  • Enhanced Recovery After Surgery
  • RNA Research and Splicing
  • Aquaculture Nutrition and Growth
  • Ginger and Zingiberaceae research
  • Amino Acid Enzymes and Metabolism
  • Gastrointestinal motility and disorders
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Water resources management and optimization
  • Fatty Acid Research and Health
  • Flood Risk Assessment and Management
  • Digestive system and related health
  • Pharmacological Effects of Natural Compounds
  • Economic and Environmental Valuation
  • RNA Interference and Gene Delivery

Northwest A&F University
2024-2025

Henan Agricultural University
2021-2024

University College London
2022

Abstract Background Coprophagy plays a vital role in maintaining growth and development many small herbivores. Here, we constructed coprophagy model by dividing rabbits into three groups, namely, control group (CON), sham-coprophagy prevention (SCP), (CP), to explore the effects of on performance cecal microecology rabbits. Results showed that CP treatment decreased feed utilization Serum total cholesterol triglyceride were remarkably lower than those other two groups. Furthermore, destroyed...

10.1186/s12866-023-02869-y article EN cc-by BMC Microbiology 2023-05-10

The intestinal microbiota and its metabolites play vital roles in host growth, development, immune regulation. This study analyzed the microbial community distribution cytokine short-chain fatty acid (SCFA) content of cecal contents (Con group), soft feces (SF hard (HF group) 60-day-old Hyplus rabbits verified effect on microenvironment by coprophagy prevention (CP). results showed that there were significant differences levels phylum genus composition, cytokines, SCFAs among Con group, SF...

10.1155/2022/5725442 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-10-30

The SLC7A5 gene encodes a Na+ and pH-independent transporter protein that regulates cell growth by regulating the uptake of AA. This study, utilizing RNA-seq, aimed to explore effect on synthesis milk proteins fats in goat mammary epithelial cells (GMECs) through interference overexpression techniques. results demonstrated resulted significant increase expression CSN1S1, SCD, CEBPB, ACACA, αS1-casein, p-S6K, p-S6. levels p-S6K p-S6 gradually increased as AA/Leu stimulation time lengthened....

10.1021/acs.jafc.4c02087 article EN Journal of Agricultural and Food Chemistry 2024-05-28

Abstract Supplementation of sodium butyrate (SB) has been proved to be beneficial for improving the growth performance and health animals, but its effects on rabbits have not well understood. Therefore, this study aimed investigate SB supplementation performance, meat quality, intestinal by evaluating feed intake efficiency, diarrhea index, blood cecum metabolites, cecal pH short‐chain fatty acids (SCFAs), histological staining, nutritional composition meat, gene expression profile cecum. A...

10.1002/aro2.71 article EN cc-by Animal Research and One Health 2024-06-11

In molecular biology studies, the selection of optimal reference genes is vital importance for accurately quantifying gene expression. The purpose present study was to screen most stable in different muscle tissues New Zealand white rabbits and Yufeng yellow rabbits.Results indicated that were HPRT1, ACTB PPIC, while RPL13A rabbits. However, longissimus dorsi abdominal wall both varieties, RPL13A, SDHA. quadriceps femoris muscle, ACTB, Furthermore, relative abundance MYOG, MYH3 MSTN used...

10.1186/s40850-022-00159-0 article EN cc-by BMC Zoology 2022-12-15

This study aimed to investigate how diets supplemented with DHA-rich algae affect the expression of liver lipid synthesis genes in dairy goat bucks. The results revealed that when algae, weight and serum HDL-C were significantly increased (p < 0.05), as well LDL-C was decreased 0.05). Transcriptome sequencing indicated supplementation alters gene expression. differentially expressed predominantly enriched fatty acid metabolism biosynthesis unsaturated acids. desaturation transcription...

10.3390/agriculture14050685 article EN cc-by Agriculture 2024-04-27

Abstract Acetic acid, which is one of the most abundant short-chain fatty acids (SCFA) in rabbits’ cecum, has been reported to play an important function during various physiological metabolic processes. The present study was conducted elucidate effects sodium acetate on growth performance and intestinal health by evaluating feed intake efficiency, diarrhea score, serum cecum metabolites, cecal pH SCFA, histological staining, nutritional composition meat gene expression profile rabbits. As a...

10.1093/jas/skae197 article EN Journal of Animal Science 2024-01-01

Temporary flood defenses constitute a supplementary approach to permanent engineering solutions for management. However, their deployment strategy is challenge because it depends on uncertain short-term weather conditions. The strategies that later proved be insufficient or underused can have high social and environmental costs. Real options analysis (ROA) provides mechanism include flexibility in decision making adapt the future conditions handle aforementioned temporary planning. To apply...

10.1061/(asce)wr.1943-5452.0001551 article EN Journal of Water Resources Planning and Management 2022-04-15

Abstract Background : Intestinal microbiota and its metabolites play a vital role in host growth, development immune regulation. Methods This study analyzed the microbial community distribution, cytokines short chain fatty acids (SCFAs) content of cecal contents (Con) group, soft feces (SF) group hard (HF) 140-day-old Hyplus rabbits, verified effect on microenvironment by fasting feces. Results The results showed that there were significant differences levels phylum genus composition, SCFAs...

10.21203/rs.3.rs-1047430/v1 preprint EN cc-by Research Square (Research Square) 2021-11-15
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