Roberto de la Rica

ORCID: 0000-0002-5750-1469
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About
Contact & Profiles
Research Areas
  • Biosensors and Analytical Detection
  • Advanced biosensing and bioanalysis techniques
  • Advanced Biosensing Techniques and Applications
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Supramolecular Self-Assembly in Materials
  • SARS-CoV-2 detection and testing
  • Analytical Chemistry and Sensors
  • Diatoms and Algae Research
  • Advanced Chemical Sensor Technologies
  • COVID-19 Clinical Research Studies
  • Advanced Nanomaterials in Catalysis
  • Respiratory viral infections research
  • Nanocluster Synthesis and Applications
  • Long-Term Effects of COVID-19
  • Advanced Sensor and Energy Harvesting Materials
  • Molecular Junctions and Nanostructures
  • Nanoparticle-Based Drug Delivery
  • Microfluidic and Bio-sensing Technologies
  • Laser-Ablation Synthesis of Nanoparticles
  • SARS-CoV-2 and COVID-19 Research
  • Force Microscopy Techniques and Applications
  • Nanofabrication and Lithography Techniques
  • Advanced Photocatalysis Techniques
  • Nanowire Synthesis and Applications
  • Quantum Dots Synthesis And Properties

Health Research Institute of the Balearic Islands
2018-2025

Centro de Investigación Biomédica en Red
2022-2025

Instituto de Salud Carlos III
2022-2025

Hospital Universitario Son Espases
2020-2024

University of Strathclyde
2015-2023

Universitat de les Illes Balears
2017-2022

Clinica Rotger
2017-2021

Hospital Son Llatzer
2020

Glasgow Life
2016

Imperial College London
2012-2015

Colorimetric wearable biosensors made of paper detect glucose in sweat using a smartphone as reader. Measurements correlated well with blood levels, these devices could be used “over-the-counter” tests for monitoring glucose.

10.1039/d1an00283j article EN cc-by The Analyst 2021-01-01

Paper sensors with colorimetric signal transduction mechanisms are promising for developing single-use wearable patches that only require a smartphone to quantify signals. However, measuring biomarker fluctuations requires implementing chrono-sampling method performing sequential measurements. In this article, we report on enables the fabrication of devices made entirely filter paper. It consists using dried polymers as closed valves deflect flow liquids different transducers multisensor. As...

10.1021/acssensors.1c02244 article EN ACS Sensors 2022-02-16

There is limited information available describing the clinical and epidemiological features of Spanish patients requiring hospitalization for coronavirus disease 2019 (COVID-19). In this observational study, we aimed to describe characteristics severe (non-ICU) critically (ICU) with COVID-19 at triage, prior hospitalization. Forty-eight (27 non-ICU 21 ICU) positive acute respiratory syndrome 2 (SARS-CoV-2) infection were analyzed (mean age, 66 years, [range, 33-88 years]; 67% males). no...

10.3390/microorganisms8081106 article EN cc-by Microorganisms 2020-07-24

Detecting small variations in the levels of IL-6 is crucial for early diagnosis sepsis. To be useful clinical decision-making, this requires detecting rapidly whole blood and with portable readers. Here we introduce immunosensors made filter paper that use plasmonic nanoprobes to detect unprocessed an unmodified smartphone. Key aspects biosensor fabrication were optimized order reduce assay time without losing sensitivity. This included testing three bioconjugation routes protein attachment...

10.1039/d0na00026d article EN cc-by-nc Nanoscale Advances 2020-01-01

In this manuscript, we introduce a wearable analytical platform that simultaneously measures the concentration of sweat lactate and sample volume. It contains two sensors entirely made filter paper can be easily affixed on skin with medical-grade tape. The biosensor features unique signal modulation mechanism enables fine-tuning dynamic range. consists adding competitive enzyme inhibitor in different reservoirs. Thanks to this, it is possible choose between very low limit detection (0.06 mM)...

10.1021/acssensors.0c01980 article EN ACS Sensors 2020-12-29

Reactor core: Hybrid core–shell urease–ZnO nanostructures have been synthesized (see picture). The crystallization takes place under mild biological conditions, thus ensuring its easy implementation in other room-temperature syntheses of oxide semiconductor materials. Supporting information for this article is available on the WWW http://www.wiley-vch.de/contents/jc_2002/2008/z801181_s.pdf or from author. Please note: publisher not responsible content functionality any supporting supplied by...

10.1002/anie.200801181 article EN Angewandte Chemie International Edition 2008-06-09

A robust viral sensor was developed by bridging a pair of gold electrodes with antibody-coated peptide nanotubes. The nanotubes concentrated the target virus on their surface molecular recognition between antibody and (see picture). fit perfectly within electric field line distribution to enable extremely sensitive impedimetric detection particles. Detailed facts importance specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or...

10.1002/anie.200804299 article EN Angewandte Chemie International Edition 2008-11-06

Abstract This feature article highlights our recent applications of functional peptide nanotubes, self‐assembled from short peptides with recognition elements, as building blocks to develop sensors. Peptide nanotubes high aspect ratios are excellent for a directed assembly into device configurations, and their combined structures nanometric diameters micrometric lengths enables bridge the “nanoworld” “microworld”. When peptide‐nanotube‐based biosensors, which incorporate molecular units,...

10.1002/adfm.201001419 article EN Advanced Functional Materials 2011-03-01

The technique of plasmonic ELISA is successfully applied to detect the HIV protein gp120 at ultralow concentration 10 × 10<sup>−17</sup> g mL<sup>−1</sup>.

10.1039/c3nr06167a article EN Nanoscale 2014-01-01

ABSTRACT OBJECTIVE To describe the clinical characteristics and epidemiological features of severe (non-ICU) critically patients (ICU) with COVID-19 at triage, prior hospitalization, in one main hospitals The Balearic Islands health care system. DESIGN Retrospective observational study SETTING Son Llatzer University Hospital Palma de Mallorca (Spain) PARTICIPANTS Among a cohort 52 hospitalized as 31 March 2020, 48 complete demographic information acute respiratory syndrome coronavirus 2...

10.1101/2020.05.07.20094987 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-05-11

Colorimetric tests are becoming increasingly popular in point-of-need analyses due to the possibility of detecting signal with naked eye, which eliminates utilization bulky and costly instruments only available laboratories. However, colorimetric may be interpreted incorrectly by nonspecialists disparities color perception or a lack training. Here we solve this issue method that not detects signals but also interprets them so test outcome is understandable for anyone. It consists an...

10.1021/acssensors.7b00259 article EN ACS Sensors 2017-05-26

Identifying the pathogen responsible for an infection is a requirement in order to personalize antimicrobial treatments. Detecting bacterial enzymes, such as proteases, lipases, and oxidoreductases, winning approach detecting pathogens at point of care. In this Article, new method urease-producing bacteria rapidly ultralow concentrations reported. method, longsome bacteriological culture steps are substituted 10 min capture procedure with positively charged magnetic beads. The presence...

10.1021/acssensors.9b00063 article EN ACS Sensors 2019-03-14
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