A5044430674- Bone Tissue Engineering Materials
- Advanced biosensing and bioanalysis techniques
- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- RNA Interference and Gene Delivery
- Tissue Engineering and Regenerative Medicine
- Gold and Silver Nanoparticles Synthesis and Applications
- Supramolecular Self-Assembly in Materials
- Biosensors and Analytical Detection
- Lipid Membrane Structure and Behavior
- Osteoarthritis Treatment and Mechanisms
- Dental Implant Techniques and Outcomes
- biodegradable polymer synthesis and properties
- Nanoparticle-Based Drug Delivery
- Spectroscopy and Chemometric Analyses
- Graphene and Nanomaterials Applications
- Advanced Nanomaterials in Catalysis
- Cellular Mechanics and Interactions
- Extracellular vesicles in disease
- Neuroscience and Neural Engineering
- Orthopaedic implants and arthroplasty
- Polymer Surface Interaction Studies
- Nanoplatforms for cancer theranostics
- Force Microscopy Techniques and Applications
Imperial College London
2016-2025
NIHR Imperial Biomedical Research Centre
2016-2025
Karolinska Institutet
2016-2025
University of Oxford
2023-2025
University of Pennsylvania
2024-2025
Institute for Biomedical Engineering
2019-2023
National and Kapodistrian University of Athens
2023
Material Sciences (United States)
2022
Early Warning (United States)
2022
Vrije Universiteit Amsterdam
2022
Materials that enhance bone regeneration have a wealth of potential clinical applications from the treatment nonunion fractures to spinal fusion. The use porous material scaffolds bioceramic and polymer components support cell tissue growth is longstanding area interest. Current challenges include engineering materials can match both mechanical biological context real matrix vascularization large constructs. Scaffolds with new levels biofunctionality attempt recreate nanoscale topographical...
A microvalve-based bioprinting system for the manufacturing of high-resolution, multimaterial 3D-structures is reported. Applying a straightforward fluid-dynamics model, shear stress at nozzle site can precisely be controlled. Using this system, broad study on how cell viability and proliferation potential are affected by different levels conducted. Complex, 3D structures printed with high resolution. This work pioneers investigation stress-induced damage in might help to comprehend improve...
Curving bones On larger length scales, bone is known to have a hierarchical structure in which small crystals of calcium phosphates arrange themselves around helices collagen. These make up structures, such as the osteons found compact bone. However, at smaller lengths, does persist? By combining three-dimensional electron tomography with two-dimensional microscopy, Reznikov et al. observed structural ordering from nanoscale upward. At smallest scale, needle-shaped mineral units form...
Mineralization is a ubiquitous process in the animal kingdom and fundamental to human development health. Dysfunctional or aberrant mineralization leads variety of medical problems, so an understanding these processes essential their mitigation. Osteoblasts create nano-composite structure bone by secreting collagenous extracellular matrix (ECM) on which apatite crystals subsequently form. However, despite requisite function building decades observations describing intracellular calcium...
Embryonic stem cells (ESC) are both a potential source of for tissue replacement therapies and an accessible tool to model early embryonic development. Chemical factors such as soluble growth insoluble components the extracellular matrix known affect differentiation murine ESCs. However, there is also evidence suggest that undifferentiated can sense mechanical properties their environment differentiate accordingly. By growing ESCs on flexible polydimethylsiloxane substrates with varying...
Paper-based lateral flow immunoassays (LFIAs) are one of the most widely used point-of-care (PoC) devices; however, their application in early disease diagnostics is often limited due to insufficient sensitivity for requisite sample sizes and short time frames PoC testing. To address this, we developed a serum-stable, nanoparticle catalyst-labeled LFIA with surpassing that both current commercial published sensitivities paper-based detection p24, earliest conserved biomarkers HIV. We report...