A5091052964- Forensic and Genetic Research
- HIV, Drug Use, Sexual Risk
- Maternal and Neonatal Healthcare
- Race, Genetics, and Society
- Indigenous Health and Education
- HIV/AIDS Research and Interventions
- Hepatitis B Virus Studies
- Youth, Drugs, and Violence
- Public Health in Brazil
- Phytochemistry Medicinal Plant Applications
- Molecular Biology Techniques and Applications
- Women's cancer prevention and management
- Healthcare Regulation
- Science and Education Research
- Quality and Safety in Healthcare
- Mosquito-borne diseases and control
- Hepatitis C virus research
- Ginkgo biloba and Cashew Applications
- Pharmaceutical Practices and Patient Outcomes
- Patient Safety and Medication Errors
- Genetic diversity and population structure
- Sex work and related issues
- Genomics and Phylogenetic Studies
- Metabolism and Genetic Disorders
- History and Politics in Latin America
Universidade Federal do Amapá
2016-2023
Universidade Federal do Pará
2010-2016
The non-recombining nature of the Y chromosome and well-established phylogeny Y-specific Single Nucleotide Polymorphisms (Y-SNPs) make them useful for defining haplogroups with high geographical specificity; therefore, they are more apt than Y-STRs to detect population stratification in admixed populations from diverse continental origins. Different Y-SNP typing strategies have been described address issues history movements within geographic territories interest. In this study, we...
Diabetes mellitus is a chronic and severe metabolic dysfunction, it's slow progressive evolution interferes directly in the metabolism of carbohydrates, fats proteins, causing hyperglycemia, glycosuria, polydipsia, hyperlipidaemia, among others. The aim this study was to evaluate antidiabetic effect hydroethanolic extract granulated Calophyllum brasiliense Cambess., Clusiaceae, species diabetic rats as well biochemical parameters. results demonstrated that both pharmaceutical forms,...
Elevated rates of Hepatitis C Virus (HCV) infection have been reported in epidemiological studies with people who used illicit drugs (PWUIDs) different Brazilian regions. In Brazil's Amazon region, already identified the common use among adolescents and high prevalence HCV infections PWUIDs. However, all done PWUIDs were conducted small samples within limited geographic coverage. This study determined risk factors for northern Brazil, as well estimating associated spontaneous clearance (HSC).
Abstract Objectives. In this study, we aimed to identify ancestry informative haplotypes and make interethnic admixture estimates using X‐chromosome markers. Methods. A significant sample (461 individuals) of European, African, Native American populations was analyzed, four linkage groups were identified. The data obtained used describe the ancestral contribution from different geographical regions Brazil (745 individuals). Results. global mixed under investigation calculated applying all 24...
People who use illicit drugs (PWUDs) have a high risk of viral infections. To date, there is paucity information on HIV infection among PWUDs in remote Brazilian regions. This study determined the prevalence and factors associated with HIV-1 northern Brazil.Sociodemographic, economic, drug health-related were collected through interviews from community-recruited, multi-site sample 1753 PWUDs. The blood samples tested for presence using chemiluminescence immunoassay PCR or western blotting....
The valley of the Magdalena River is one main population pathways in Colombia. gene pool and spatial configuration human groups this territory have been outlined throughout three historical stages: Native pre-Hispanic world, Spanish colonization, XIX century migrations. This research was designed with goal characterizing diversity distribution pattern Y-chromosome lineages that are currently present Tolima Huila departments (middle region). Historic cartography used to identify geographic...
Background: Several records of high prevalence HBV have been made in northern Brazil. Among risk groups for viral infection, people who use illicit drugs (PWUDs) stand out, especially if they inject and engage risky sexual behavior. Objectives: In this study, the prevalence, genotype distribution factors associated with hepatitis B virus (HBV) exposure PWUDs were estimated. Methods: This cross-sectional study used snowball sampling from nine different sites. Socio-demographic, economic, drug...
Hepatitis B (HBV) and delta (HDV) viruses are endemic in the Amazon region, but vaccine coverage against HBV is still limited. People who use illicit drugs (PWUDs) represent a high-risk group due to common risk behavior socioeconomic factors that facilitate acquisition transmission of pathogens. The present study assessed presence HBV-HDV co-infection, identified viral sub-genotypes, verified occurrence mutations coding regions for HBsAg part polymerase HBV-infected PWUDs municipalities...
The polymorphisms Arg72Pro in the TP53 gene (rs1042522) and Ile655Val HER2 (rs1136201) have been related to susceptibility several types of cancer. Different studies show association these with breast cancer, so our aim this study was investigate whether any influence on risk developing cancer women from city Macapá, Amapá, located brazilian amazon region.We then analyzed 80 DNA samples 83 without disease, by Restriction Fragment Length Polymorphism - Polymerase Chain Reaction (PCR-RFLP)...
The rates of syphilis and viral co-infections among people who use crack-cocaine (PWUCC) were assessed in this study. This cross-sectional study relied on biological self-reported socio-behavioral data from a convenience sample 990 PWUCC twenty-six municipalities the states Amapá Pará, northern Brazil. Blood samples collected to assess presence
Newborn screening comprises a set of tests that aim to detect pathologies in newborns and should be performed preferably between the 3rd 7th month life. The scree-ning detects six congenital anomalies: phenylketonuria, hypothyroidism, sickle cell anemia, cystic fibrosis, biotinidase deficiency, adrenal hyperplasia. According Ministry Health, 2007 state Amapá had lowest population coverage for Brazil. Through qualitative methodology, institu-tional data were collected reference laboratory...
Introduction: Patients admitted to Intensive Care Units (ICU) are submitted multiple drug treatments, considering the severity of their problems. Drug interaction is defined as an event caused by modification effect or use a in body. The evaluation potential interactions can help multiprofessional team promote quality treatment, avoiding harmful interactions, reducing length hospitalization and consequently costs. Objective: To evaluate main observed ICUs private hospital city Macapá,...
Bacteriophages are viruses of bacteria that have received significant attention in the last decades due to their potential as an alternative antibiotics, well applicability selective control bacterial species harmful food. In this context, work reports partial results a viral filtrate named P4CSa was obtained with bacterium Staphylococcus aureusand characterized by host range and restriction fragment length polymorphism technique. The indicate phage probably belongs order Caudovirales, it...
In the last 30 years, advances in Molecular Biology techniques have allowed its application as an essential tool criminal investigation, with a particularly relevant determination of authorship crimes and identification missing persons unknown corpses. However, popularization Forensic Genetics growth violence, there has been significant increase demand for these tests, which led Laboratories to search more efficient safe methods processing this increasing volume samples. sense, automation...
O estupro é um crime que, muitas vezes, não deixa vestígios ou estes desaparecem após determinado período de tempo dificultando as investigações criminais. Desta forma, necessário a utilização técnicas forenses detecção que contribuam com justiça e auxiliem na elucidação dos fatos dinâmica do crime. objetivo deste trabalho é, através uma pesquisa descritiva laboratorial, avaliar o manchas sangue em três tipos tecidos utilizando os testes Kastle-Meyer HemDirect® , no 50 dias, intervalo 3 dias...
Bacteriófagos Agentes anti-infecciosos AntimicrobianoBacteriófagos ou fagos, são vírus que infectam e matam bactérias com grande seletividade, por isso, possuem aplicabilidade terapêutica biotecnológica para o controle de forma abrangente especifica em função sua amplitude hospedeiros, seja, a capacidade infectar lisar diferentes espécies bacterianas.O os potencializa como uma poderosa ferramenta biocontrole bacteriano, incluindo patógenos, principalmente um contexto na qual resistência...
Iron deficiency anemia mostly affects children and adolescents, women of childbearing age pregnant due to their high iron requirements.The MTHFR enzyme helps maintain the pool folate methionine, avoiding accumulation homocysteine.Patients with elevated levels homocysteine have a wide range clinical features, including anemia, because cysteine is protein derived from metabolism related homeostasis.The objective our research was determine whether gene A1298C polymorphism development in...