A5078096304- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Anesthesia and Pain Management
- Pelvic and Acetabular Injuries
- Bone health and osteoporosis research
- Orthopaedic implants and arthroplasty
- Pain Management and Opioid Use
- Orthopedic Infections and Treatments
- Hip and Femur Fractures
- Spinal Hematomas and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Bone and Joint Diseases
- Infectious Diseases and Tuberculosis
- Clinical practice guidelines implementation
- Surgical site infection prevention
- Hip disorders and treatments
- Radiation Dose and Imaging
- Nausea and vomiting management
- Shoulder Injury and Treatment
- Nutrition and Health in Aging
- Opioid Use Disorder Treatment
Hospital for Special Surgery
2016-2025
Cornell University
2016-2025
Weill Cornell Medicine
2018-2025
Nuovo Ospedale San Giovanni di Dio
2025
The Spine Institute
2020-2024
Charité - Universitätsmedizin Berlin
2021
Kelly Services (United States)
2021
Jensen Hughes (United States)
2021
NuVasive (United States)
2012
Apyx Medical (United States)
2012
Surgery for spinal stenosis is widely performed, but its effectiveness as compared with nonsurgical treatment has not been shown in controlled trials.
Management of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery widely used, but its effectiveness in comparison that nonsurgical treatment has not been demonstrated controlled trials.Surgical candidates from 13 centers 11 U.S. states who had at least 12 weeks symptoms and image-confirmed were offered enrollment a randomized cohort or an observational cohort. Treatment was standard decompressive laminectomy (with without fusion) usual care. The primary outcome...
Many approaches are used to repair skeletal defects in reconstructive orthopaedic surgery, and bone grafting is involved virtually every procedure. The type of graft depends on the clinical scenario anticipated final outcome. Autogenous cancellous graft, with its osteogenic, osteoinductive, osteoconductive properties, remains standard for grafting. However, high incidence morbidity during autogenous harvest may make acquisition grafts from other sources desirable. applications each dictated...
COMPARED2][3] Results for the Spine Patient Outcomes Research Trial (SPORT) randomized trial intervertebral disk herniation are reported in a companion article.In that study, both surgical and nonoperative patients experienced significant improvement over time intent-to-treat analyses showed no differences between groups primary outcome measures.Randomized trials of surgery face number challenges 4 their gen-See also pp 2441, 2483, 2485.
In Brief Study Design. Randomized trial and concurrent observational cohort study. Objective. To compare 4 year outcomes of surgery to nonoperative care for spinal stenosis. Summary Background Data. Surgery stenosis has been shown be more effective compared treatment over 2 years, but longer-term data have not analyzed. Methods. Surgical candidates from 13 centers in 11 US states with at least 12 weeks symptoms confirmatory imaging were enrolled a randomized (RC) or (OC). Treatment was...
Study Design. A prospective study randomized by patient choice from the private practice of a single physician affiliated with major teaching hospital was conducted. Objectives. To compare transforaminal epidural steroid injections saline trigger-point used in treatment lumbosacral radiculopathy secondary to herniated nucleus pulposus. Summary Background Data. Epidural have been for more than half century management radicular pain. At this writing, however, there no controlled trials lumbar...
In Brief Study Design. A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial. Objective. To evaluate the safety effectiveness of ProDisc®-L (Synthes Spine, West Chester, PA) lumbar total disc replacement compared to circumferential spinal fusion for treatment discogenic pain at 1 vertebral level between L3 S1. Summary Background Data. As part trial, favorable single center results with have been reported previously....
Background: Surgical site infection in the spine is a serious postoperative complication. Factors such as posterior surgical approach, arthrodesis, use of spinal instrumentation, age, obesity, diabetes, tobacco use, operating-room environment, and estimated blood loss are well established literature to affect risk infection. The goal this study was analyze identify independent factors for among patients undergoing lumbar instrumented arthrodesis. Methods: medical records 3218 who underwent...
A retrospective chart review was conducted for 112 patients who underwent revision posterior lumbar spine decompression, fusion, and segmental instrumentation.To ascertain factors predicting hospital stay, operative time, blood loss, transfusion in undergoing instrumentation.Posterior decompression fusion with instrumentation is a common procedure the treatment of degenerative disorders. Many this have had previous surgery, yet little known about transfusion.The charts (53 men 59 women)...
A retrospective review of patients' radiographs and charts.The various methods lumbar interbody fusion have been described in the literature. With development lateral (LLIF) approach, a wider cage can be inserted intervertebral space without disrupting anterior-posterior annulus or longitudinal ligament, with minimal danger to retroperitoneal structures great vessels. There is paucity literature on radiographic clinical outcome this approach.The purpose study assess change coronal sagittal...
A retrospective review of lumbar total disc replacement (TDR) radiographs.To determine the error and variability in measuring TDR radiographic range motion (ROM).Motion preservation is driving force behind technology. In recent literature, sagittal ROM as low 2 degrees has been reported. these studies, was determined by using Cobb method to measure alignment angles flexion-extension lateral radiographs. However, previous studies spinal deformity literature have shown that very susceptible...
Background: Symptomatic lumbar degenerative disc disease is a challenging entity to treat. The results of arthrodesis may be compromised in the short term by pseudarthrosis and long pain at iliac-crest donor site junctional degeneration. Total replacement has potential provide long-lasting relief these patients. purpose this study was present clinical radiographic assessed seven eleven years following Prodisc total replacement. Methods: Sixty-four patients had single or multiple-level...
Multicenter, prospective equivalency trial with each patient serving as his/her own control.To compare the effectiveness of a Grafton DBM gel composite iliac crest autograft in posterolateral spine fusion.While remains preferred graft material to facilitate fusion, supply is limited and harvesting produces undesirable clinical consequences.A total 120 patients underwent fusion pedicle screw fixation bone grafting. Iliac was implanted on one side DBM/autograft contralateral same patient. An...
Retrospective chart review.To examine the incidence of major vascular injury during anterior lumbar spinal surgery, attempt to identify predisposing risk factors, and discuss management techniques.Major can be a catastrophic complication surgery.Current procedural terminology codes were used occurrence injury, defined as iliac vessels, vena cava, aorta. Once identified, office record, hospital chart, operative note, diagnostic test results reviewed in detail.Three hundred forty-five...
Age-related changes in the spinal column result a degenerative cascade known as spondylosis. Genetic, environmental, and occupational influences may play role. These spondylotic direct compressive ischemic dysfunction of cord cervical myelopathy (CSM). Both static dynamic factors contribute to pathogenesis. CSM present subclinical stenosis or follow more pernicious progressive course. Most reports natural history involve periods quiescent disease with intermittent episodes neurologic...
Low back pain as a result of degenerative disc disease imparts large socioeconomic impact on the health care system. Traditional concepts for treatment lumbar degeneration have aimed at symptomatic relief by limiting motion in spine, but novel strategies involving stem cells, growth factors, and gene therapy theoretical potential to prevent, slow, or even reverse degeneration. Understanding pathophysiological basis is essential development that target underlying mechanisms rather than...
Lateral transpsoas interbody fusion (LTIF) permits anterior column lumbar via a direct lateral approach. The authors sought to answer 3 questions. First, what is the effect of LTIF on foraminal area? Second, how does cage placement affect intervertebral height? And third, change in area and position correlate with changes Oswestry Disability Index (ODI) 12-Item Short Form Health Survey (SF-12) scores?Included patients underwent or without posterior instrumentation received preoperative...
In Brief Study Design. Retrospective case-control study. Objective. To determine the association of Hounsfield unit (HU) measurements with adjacent segment fractures after spinal fusion. Summary Background Data. Adjacent fracture is a potentially devastating complication fusion surgery in osteoporotic patient. Recently, technique for assessing bone mineral density using HU from computed tomography was described and correlated both dual-energy x-ray absorptiometry–assessed compressive...
A cohort study of nonoperatively treated patients with lumbar spinal stenosis.To assess the effectiveness aggressive nonsurgical treatment for stenosis.While surgical stenosis has been widely accepted, natural history this condition is poorly documented. Moreover, effect other available therapies unclear.Forty-nine meeting radiographic and clinical criteria underwent intervention consisting therapeutic exercises, analgesics, epidural steroid injections. Patients were followed an average 33...