A5059355853- Respiratory Support and Mechanisms
- Ultrasound in Clinical Applications
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Venous Thromboembolism Diagnosis and Management
- Mechanical Circulatory Support Devices
- Radiation Dose and Imaging
- Thermal Regulation in Medicine
- Anesthesia and Sedative Agents
- Neonatal Respiratory Health Research
- COVID-19 and healthcare impacts
- Veterinary Pharmacology and Anesthesia
- Esophageal and GI Pathology
- Healthcare Technology and Patient Monitoring
- Inhalation and Respiratory Drug Delivery
- Birth, Development, and Health
- Trauma and Emergency Care Studies
- Cardiovascular and Diving-Related Complications
- Gastroesophageal reflux and treatments
- Pericarditis and Cardiac Tamponade
- Dysphagia Assessment and Management
- Ultrasound and Hyperthermia Applications
University of Pavia
2010-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2023
Policlinico San Matteo Fondazione
2015-2023
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2020
University of Parma
2020
Intensive Care Foundation
2019
Lung ultrasound is commonly used to evaluate lung morphology in patients with acute respiratory distress syndrome. Aim of this study was determine reliability assessing aeration and positive end-expiratory pressure-induced recruitment compared CT.Randomized crossover study.University hospital ICU.Twenty sedated paralyzed syndrome patients: age 56 years (43-72 yr), body mass index 25 kg/m (22-27 kg/m), PaO2/FIO2 160 (113-218).Lung CT examination were performed at pressure 5 15 cm H2O.Global...
Abstract Purpose Lung Ultrasound Score (LUSS) is a useful tool for lung aeration assessment but presents two theoretical limitations. First, standard LUSS based on longitudinal scan and detection of number/coalescence B lines. In the pleura visualization limited by intercostal space width. Moreover, coalescence lines to define severe loss not suitable non-homogeneous pathologies where focal possible. We therefore compared vs. transversal also cLUSS (standard coalescence-based LUSS) qLUSS...
Whether respiratory efforts and their timing can be reliably detected during pressure support ventilation using standard ventilator waveforms is unclear. This would give the opportunity to assess improve patient-ventilator interaction without need of special equipment.In 16 patients under invasive ventilation, flow were obtained from proximal sensors analyzed by three trained physicians one resident patient's spontaneous activity. A systematic method (the waveform method) based on explicit...
In ARDS, the PEEP level associated with best respiratory system compliance is often selected; however, intra-tidal recruitment can increase compliance, falsely suggesting improvement in baseline mechanics. Tidal lung hysteresis increases and help interpreting changes compliance. This study aims to assess tidal ARDS patients test a combined approach, based on interpret decremental trials.A trial was performed 38 COVID-19 moderate severe patients. At each step, we low-flow inflation-deflation...
Background: Pressure support ventilation is frequently associated with patient-ventilator asynchrony. Algorithms based on ventilator waveforms have been developed to automatically detect patient respiratory activity and guide triggering cycling. The aim of this study was assess the performance in terms synchronization 6 mechanical ventilators, all provided a waveform-guided software. Methods: This bench compare standard new-generation systems simulating different mechanics, levels...
Esophageal balloon calibration was proposed in acute respiratory failure patients to improve esophageal pressure assessment. In a clinical setting characterized by high variability of abdominal load and intrathoracic (i.e., pelvic robotic surgery), the authors hypothesized that could measurements. Accordingly, assessed impact compared conventional uncalibrated approach during surgery.In 30 adult patients, scheduled for elective surgery, calibrated end-expiratory end-inspiratory pressure,...
Lung ultrasound is a bedside non-irradiating tool for assessment and monitoring of lung diseases. A score based on visualized artefacts allows reliable quantification aeration, useful to monitor mechanical ventilation setting, fluid resuscitation antibiotic response in critical care. In the context interstitial diseases associated connective tissue disorders, has been integrated computed tomography diagnosis follow-up chronic disease progression.This case describes severe acute exacerbation...
Lung ultrasound has greatly developed in the last decade, becoming increasingly important both for diagnosis and monitoring of acute respiratory failure; it can be used on a daily basis at bedside to improve clinical assessment critically ill. This review describes how lung assess patients with distress syndrome (ARDS), from initial management monitoring. Quantification aeration performed score; is reliable when compared computed tomography scan, easy learn, repeatable. It guide mechanical...
We describe the case of a 49-year-old woman with Tramadol intoxication associated multiorgan failure. Veno-arterial femoro-femoral extracorporeal life support (VA-ECLS) and hemoperfusion (HP) were used as rescue treatments. The emergency medical service found at home unconscious. Once in hospital, she was intubated catecholamines immediately started for severe shock. Brain CT normal, whereas EEG revealed metabolic encephalopathy pattern. Toxic levels Quetiapine detected. VA-ECLS implanted...
Supportive care is the cornerstone of poisoned patient's treatment, waiting for eventual antidotes to act. We recently treated a case severe Ethylene Glycol intoxication with early-onset veno-arterial ECMO. The patient was taken our Emergency Department suspicion acute cerebrovascular accident, since he found unconscious at home. arterial blood gas and tests showed metabolic acidosis high serum lactates creatinine levels. cerebral Computed Tomography negative. rapid increase in suggested...
Lung ultrasound (LUS) allows semiquantification of lung aeration in PEEP trials [1], pneumonia [2] and weaning [3]. LUS score is based on number/coalescence vertical artifacts (B-lines) longitudinal scan (LONG) [4]: the pleura identified between two ribs its visualization limited by intercostal space (ICS) width. We hypothesized that a transversal (TRANSV) aligned with ICS would visualize longer higher number artifacts, better assessment loss (LoA).
Plateau pressure (Pplat) limitation is routinely used to avoid ventilator-induced lung injury. Recently, driving (ΔP) was strongly associated with survival in ARDS patients [1].
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The need of heat exchanger in the ECMO circuit is controversial. Moreover, how to monitor patient central temperature during extracorporeal support still not clear, but potentially useful for detection “unexpressed” fever, eventually related septic complications.
<b>Background:</b> lung ultrasound(LUS) score allows reliable quantification of loss aeration[1] and was applied to monitor aeration[2]. <b>Aims:</b> To determine if LUS early identifies responders non-invasive respiratory support. <b>Methods:</b> prospective observational multicenter study. Hypoxemic patients(PaO2/FiO2<300) with clinical indication support (high-flow nasal cannula-HFNC, continuous positive airways pressure-CPAP). Non-responders required intubation within 48h....
Oesophageal pressure is increasingly used to monitor and manage mechanically ventilated patients. Even if the oesophageal balloon catheter correctly positioned, measurement can be affected by inappropriate filling and/or reaction inflation. We aimed assess in