- Pharmaceutical and Antibiotic Environmental Impacts
- Effects and risks of endocrine disrupting chemicals
- Toxic Organic Pollutants Impact
- Bacterial Genetics and Biotechnology
- Diet, Metabolism, and Disease
- Plant nutrient uptake and metabolism
- Enzyme Structure and Function
- Carcinogens and Genotoxicity Assessment
- GABA and Rice Research
- Pesticide Residue Analysis and Safety
- Marine animal studies overview
- Pharmacogenetics and Drug Metabolism
- Enzyme Production and Characterization
- Meat and Animal Product Quality
- Reproductive biology and impacts on aquatic species
- Molecular Sensors and Ion Detection
- Dye analysis and toxicity
- Phytoestrogen effects and research
- Phytochemical and Pharmacological Studies
- Viral Infectious Diseases and Gene Expression in Insects
- Food Waste Reduction and Sustainability
- Polyamine Metabolism and Applications
- Antibiotic Resistance in Bacteria
- Bacillus and Francisella bacterial research
- Animal testing and alternatives
University of Liège
2007-2017
Institut de Chimie
2015
We report the first identification of a gene cluster involved in d-tagatose catabolism Bacillus licheniformis. The pathway is closely related to Gram-negative bacterium Klebsiella oxytoca, contrast 6-phosphate described Gram-positive Staphylococcus aureus.
Nowadays, endocrine disruptor compounds in the water system have become a concern due to risk of contamination wild life and humans even at nanogram level. Excess estrogens androgens are major contributor group compounds. Statistical surveys shown that dairy farms contribute over 90% total UK US. Reporter gene assays (RGAs) is being developed assess efficiency reactive materials remove target hormonal contaminants from farm wastewater. This study demonstrates 2 g (granular activated carbon...
We report the first enzymatic synthesis of <smlcap>D</smlcap>-tagatose-1-phosphate (Tag-1P) by multicomponent phosphoenolpyruvate:sugar phosphotransferase system (PEP-PTS) present in tagatose-grown cells <i>Klebsiella pneumoniae</i>. Physicochemical characterization <sup>31</sup>P and <sup>1</sup>H nuclear magnetic resonance spectroscopy reveals that, solution, this derivative is primarily pyranose form. Tag-1P was used to characterize putative...
In vitro risk assessment of dietary contaminants has become a priority in human food safety. This paper proposes an approach associating different complementary tools original toolbox and aims to improve the toxicological impact at realistic exposure levels, with special focus on intestinal compartment. The system is based use four cellular tools, namely stress gene induction transgenic strains Escherichia coli, modulation activity key biotransformation enzymes (cytochrome P-450 (CYP) 1A1...
Nowadays, endocrine disruptor compounds in the water system have become a concern due to risk of contamination wild life and humans even at nanogram level. Excess estrogens androgens are major contributor group compounds. Statistical surveys shown that dairy farms contribute over 90% total UK US. An analytical is being developed assess efficiency reactive materials remove target hormonal contaminants from farm effluent. This can be achieved using reporter gene assays (RGAs) detect low level...
In PBP4a, a Bacillus subtilis class-C1 penicillin-binding protein (PBP), four clustered lysine (K) residues, K86, K114, K119, and K265, protrude from domain II. Replacement of these amino acids with glutamine (Q) residues by site-directed mutagenesis yielded Mut4KQ PBP4a. When produced in Escherichia coli without its predicted Sec-signal peptide, wild-type (WT) PBP4a was found mainly associated the host cytoplasmic membrane, whereas remained largely unbound. After purification, capacities...